Sağlık Bilimleri Üniversitesi

Neural Gas Network-Based Distinction Between Brain Cysts and Tumors from Magnetic Resonance Images Using a Hybrid Deep Learning Algorithm

The early and accurate diagnosis of brain tumors is critically important, as timely intervention significantly reduces mortality and improves patient outcomes. While magnetic resonance imaging (MRI) is the preferred diagnostic tool, differentiating malignant brain tumors from ben...

Acute exercise-related changes in hematological parameters and lymphocyte subsets before and after short‑term rapid weight loss in national‑level wrestlers: a pilot study

Abstract Background Rapid weight loss (RWL) is commonly used by wrestlers to qualify for lower weight categories, but the combined effects of RWL and intense exercise on circulating immune cell profiles, particularly lymphocyte subsets, remain incompletely characterized. This stu...

Follicular-Fluid Organic Acid Profiling in Polyendocrine Metabolic Ovarian Syndrome, Poor Responders, and Controls

Follicular-fluid (FF) organic acid concentrations may differ among women with normal ovarian reserve (NOR), polyendocrine metabolic ovarian syndrome (PMOS), and poor ovarian response (POR), reflecting alterations in central carbon and amino-acid-related metabolic pathways. PMOS a...

Effect of Sodium–Glucose Cotransporter-2 Inhibitor Use on Bowel Preparation Quality in Patients with Type 2 Diabetes Mellitus Undergoing Colonoscopy: A Prospective Comparative Observational Study

Type 2 diabetes mellitus (T2DM) is an independent risk factor for inadequate bowel preparation. Sodium–glucose cotransporter-2 (SGLT-2) inhibitors promote osmotic diuresis and natriuresis and might therefore impair preparation quality during the fluid-restricted, fasting state of...

Cytomorphological clues and progression potential according to high-risk human papillomavirus types in low-grade squamous intraepithelial lesions: An observational study

Background: Low-grade squamous intraepithelial lesions (LSILs) are frequently associated with human papillomavirus (HPV) infections; however, the cytomorphological differences among high-risk HPV (HR-HPV) genotypes remain underexplored. In this retrospective study, we aimed to as...

Ability of the HALP Score to Predict Cardiac Implantable Electronic Device‐Related Complications

BACKGROUND: The hemoglobin, albumin, lymphocyte, and platelet score (HALP) is a recently defined score that indicates patients' inflammation and nutritional status. This score is associated with poor outcomes in cardiovascular diseases. We aimed to examine the relationship betwee...

Clinical management, antifungal susceptibility, and predictors of 28-day mortality in Candidozyma auris candidemia: a single-center cohort study

Candidozyma auris (Candida auris) candidemia is a serious healthcare-associated infection with substantial mortality and limited treatment options. We retrospectively evaluated adult patients with C. auris candidemia at a tertiary care center between June 2022 and December 2025 t...

Near-complete circumferential intramural bladder gas in emphysematous cystitis: a case report

Abstract Background Emphysematous cystitis is a gas-forming infection of the urinary bladder characterized by intramural and occasionally intraluminal gas. Although diabetes mellitus is a common predisposing condition, the disease may also develop in association with urinary stas...

The relationship between parents’ child-rearing attitudes and adolescents’ self-perception

Adolescence is a critical phase for personality development. Although numerous factors influence adolescent development, parenting styles and practices are also recognised to significantly impact healthy development. Thus, the main problem of this study is to determine whether th...

Real-world outcomes of children with first relapsed acute lymphoblastic leukemia treated according to the ALL-IC REL 2016 guideline in Türkiye

Relapsed acute lymphoblastic leukemia (ALL) remains a major challenge in pediatric oncology, particularly where access to modern immunotherapies is limited. This national multicenter study evaluated real-world outcomes of children with first relapsed ALL treated according to the...

Parameters predicting mortality in antifibrotic-treated IPF patients: mMRC, CPI, TLCO, FVC, GAP

BACKGROUND: Idiopathic pulmonary fibrosis(IPF) continues to be a fatal disease despite the use of antifibrotic therapy. There is limited data on the prognostic importance of parameters predicting mortality. We aimed to identify independent mortality predictors in antifibrotic-tre...

Effects of vasopressor dose on microcirculation despite preserved macrohemodynamic targets in septic shock: a prospective observational study

Background Septic shock may be complicated by hemodynamic incoherence, in which macrohemodynamic targets are achieved despite persistent microcirculatory alterations. Whether norepinephrine requirement is associated with dynamic microvascular reactivity after initial resuscitatio...

Dynamic Changes in Serum Neutrophil Gelatinase-Associated Lipocalin for Discrimination of Creatinine-Defined Acute Kidney Injury After Laparoscopic Sleeve Gastrectomy: A Prospective Observational Cohort Study

Background/Objectives: Acute kidney injury (AKI) may occur after laparoscopic sleeve gastrectomy (LSG) as a result of obesity-related renal vulnerability, pneumoperitoneum-induced changes in renal perfusion, and perioperative hemodynamic stress. Serum creatinine remains the stand...

Mid-Term Outcomes of the Ozaki Procedure: A Single-Center Experience

BACKGROUND: To assess the midterm clinical and echocardiographic outcomes of the Ozaki (aortic valve neocuspidization (AVNeo)) procedure performed at a single center. METHODS: A total of 258 patients who underwent the AVNeo procedure between February 2019 and February 2025 were r...

A simple clinical–laboratory risk score for preoperative identification of ovarian torsion: a retrospective diagnostic study

Timely diagnosis of ovarian torsion remains challenging due to nonspecific clinical presentation and limitations of imaging. Delayed recognition may result in ovarian loss. Simple, readily available tools to support early risk stratification are therefore needed. In this retrospe...

Longitudinal Assessment of Diastolic Function and Myocardial Strain in Type 2 Diabetes: A Comparison of Empagliflozin and Linagliptin

OBJECTIVE: The cardiovascular effects of sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors have attracted increasing interest in patients with type 2 diabetes mellitus. This study aimed to compare the time-dependent effects of empagliflozin and linag...

Technique-stratified reintervention outcomes after surgical reconstruction for nutcracker syndrome: a single-center retrospective study

Nutcracker syndrome (NCS) is an uncommon venous compression disorder resulting from extrinsic compression of the left renal vein (LRV), either between the superior mesenteric artery (SMA) and the aorta (anterior NCS) or between the aorta and the vertebral body (posterior NCS). Ow...

Effectiveness of vestibular electrical stimulation combined with vestibular rehabilitation in chronic unilateral vestibular hypofunction: A randomized controlled trial

Objectives: To evaluate the effectiveness of vestibular electrical stimulation (VES) combined with vestibular rehabilitation (VR) in patients with chronic unilateral vestibular hypofunction (UVH). Patients and Methods: Forty patients aged 18-65 years, diagnosed with UVH, were ran...

Comparative Efficacy of Knee-High Versus Thigh- High Compression Stockings in Managing Chronic Venous Insufficiency: A Retrospective Comparative Cohort Study

ObjectiveTo compare the clinical efficacy and patient adherenceof knee-high versus thigh-high compression stockings,each combined with calcium dobesilate, versus pharmacologictherapy alone in the conservative managementof chronic venous insufficiency (CVI).Material and MethodThis...

Evaluation of the pSOFA Score in a Pediatric Intensive Care Unit and Its Discriminative Performance Compared with PRISM 4 and PIM 3

Objectives: We aimed to evaluate the performance of the age-adapted Pediatric Sequential Organ Failure Assessment (pSOFA) score, as a predictor of mortality in patients admitted to pediatric intensive care units (PICUs), and to compare it with the Pediatric Risk of Mortality 4 (P...