Centre National de la Recherche Scientifique

Structure andRheology of DPPC–CholesterolMonolayers

Abstract Lipids are key components of biological interfaces and are constantly subjected to external stress and shear flow. In this work, we focus on DPPC–cholesterol monolayers at water–air interfaces and study their response to compression and shear. The choice of lipids is mot...

Origin of Long‐Wavelength Variations in Crustal Thickness on Rocky Planets

Abstract Long‐wavelength crustal thickness variations are observed on telluric planets, particularly on Mars and the Moon whereas Mercury appears to lack such variations. They may stem from two early‐stage positive feedback mechanisms that can emerge in stagnant‐lid planets. Both...

Rab4b controls hepatic glucose production during fasting through glycophagy

Abstract Hepatic glucose production, essential for maintaining glycemia, is often altered in metabolic-associated fatty liver and glycogen storage diseases. Therefore, understanding the mechanisms that regulate the glucose production by hepatocyte is pivotal. Recent studies have...

Development of material monitoring protocols for nature-inclusive designed concrete units in harbor-fronts

Abstract Human activities are putting stress on earth’s ecosystems, and with increasing populations in coastal zones, the pressure on the marine environments intensifies. To accommodate the increase in anthropogenic activities in these areas, concrete is often used to adapt the c...

Nanotechnology-Enabled Remediation of Contaminated Soils: Mechanisms, Soil Constraints, Environmental Risks, and Implications for Sustainable Land Management

Engineered nanomaterials have been increasingly proposed for the treatment of contaminated soils. Nevertheless, most available evidence has been obtained in water, artificial substrates or short-term laboratory experiments, and performance in real soil is substantially more varia...

Population turnover and food-web reorganization sustain acetoclastic methanogenesis at 45 °C in tropical paddy soil

Moderately thermophilic temperatures (45 °C) are widely expected to suppress acetoclastic methanogenesis in paddy soils because thermodynamic constraints favor syntrophic acetate oxidation coupled with hydrogenotrophic pathways. However, tropical paddy soils often deviate from th...

Nuclear activities and interactome of the NS5 protein of tick-borne encephalitis virus

Orthoflaviviruses are RNA viruses responsible for significant diseases in humans, domesticated animals, and wildlife. Their NS5 protein is central in viral replication, functioning both as an RNA-dependent RNA polymerase and a methyltransferase, while also modulating cellular pro...

Multi-omics effect of contaminants exposure during embryogenesis on metamorphosis of blue mussel Mytilus edulis submitted to maritime traffic noise

Anthropogenic underwater noise is now considered one of the ‘emerging threats and ongoing challenges to biodiversity conservation’. Physiological changes have been observed in sessile invertebrates such as bivalves. Bivalve mollusks are of particular interest because of their sen...

The top 10 priorities in palliative care research in France: final results of the AXEPRO study

Prioritizing research is essential to reduce waste, particularly in palliative care, a field with historically limited investment. To identify and rank the top 10 unanswered palliative care research questions in France according to patients, caregivers, healthcare professionals a...

Vegetative Barrier Acts as a ‘Trapper’ Rather than a ‘Filter’ for Potentially Toxic Element Contaminated Wind-Erodible Particles at the Vicinity of an Industrial Brownfield: Evaluation of a Nature-Based Solution

Brownfields can represent sources of multiple contaminants and may present health risks through airborne particle dispersion and incidental soil ingestion for surrounding populations. Remediation with nature-based solutions to mitigate legacy industrial pollution is therefore a r...

Imaging in France: 2026 Update

France has seen significant advancements in radiology in recent years, driven by innovations in research and clinical practice. French groups have developed innovative imaging techniques and artificial intelligence applications in the field of diagnostic imaging and interventiona...

Planktonic foraminifera iodine ∕ calcium ratio: is it a proxy for dissolved oxygen in the ocean?

Abstract. Direct observations indicate a declining trend in ocean oxygen concentrations, which is not quantitatively captured by models. The complexity of oxygenation variability, linked to both physical and biochemical parameters, must be investigated across different modern cli...

Brick kilns across India: A temporal analysis of brick kiln distribution and technology types

Thousands of brick kilns operate across India, significantly contributing to air pollution and CO 2 emissions due to outdated practices and non-compliance with environmental standards. Regulations promoting cleaner kiln technologies have been introduced, yet detailed information...

Cerebrospinal fluid cell-free DNA sequencing in pediatric CNS tumors: towards liquid molecular neuropathology

Pediatric central nervous system tumors remain a leading cause of cancer-related mortality in children, while their diagnosis, risk stratification, and therapeutic management increasingly depend on integrated molecular characterization. However, representative tumor tissue is oft...

Compartmentalization of metals for photosynthesis and nitrogen fixation in specialized cells of the filamentous cyanobacterium Anabaena sp. PCC7120

Nitrogen fixing cyanobacteria, such as Anabaena sp. PCC7120, are some of the oldest multicellular organisms. When combined nitrogen sources are scarce, this cyanobacterium compartmentalizes photosynthesis and nitrogen fixation in vegetative cells and in differentiated heterocysts...

Total Ozone Reactivity Measurements Reveal Knowledge Gap in Volatile Organic Compound Emissions and Their Reactions

Abstract Total ozone (O 3 ) reactivity monitors (TORMs) were used to investigate biogenic volatile organic compound (BVOC) emissions from several ecosystems. Measurements were conducted in temperate deciduous North American forests, during the CABINEX and SOAS campaigns, on tundr...

Management of high-risk (B3) breast lesions in symptomatic practice: evidence review and practical recommendations for multidisciplinary care

Borderline breast lesions (B3 lesions, also termed lesions of uncertain malignant potential or high-risk lesions) represent a heterogeneous group of entities associated with variable risks of malignancy. While the management of screen-detected B3 lesions has become increasingly s...

Investigating a Devonian vertebrate assemblage with synchrotron microtomography of coprolites

Abstract Fossilised faeces (coprolites) are a unique source of information as they record palaeontological evidence of animal behaviour (autecology) as well as interactions between extinct organisms and their environment (synecology). Four samples bearing coprolites found in a ne...

The sweet spot in protein design—Where deep learning meets first principles

This Perspective explores recent methods and prospective ideas for developing hybrid AI-physics-based pipelines for protein and antibody de novo design. We argue that the highest-confidence candidates emerge where deep learning and first-principles models agree, a "sweet spot" th...

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

About 50 years after their development, the benzimidazole anthelmintic drugs still occupy a key role in the treatment of parasitic diseases. Like other anti-infective drugs, their extensive use has led to resistance development and now requires new solutions to treat these diseas...