Centre National de la Recherche Scientifique

Asymmetric bloom lengthening drives high-latitude ocean chlorophyll accumulation imbalance

Terrestrial ecosystems maintain a stable time-allocation budget between growth and senescence, but whether this applies to the ocean remains unclear. Using fused satellite LiDAR and ocean-color data (2007–2022), we show that marine phenology is variable and asymmetric. In high la...

Autotaxin induces fibrosis in lamina cribrosa cells in glaucoma

Lysophosphatidic acid (LPA) and the enzyme that generates it, autotaxin, have been shown to play a role in fibrosis in the trabecular meshwork in glaucoma, contributing to increased intraocular pressure. We wished to investigate the role of LPA and autotaxin in fibrosis of the la...

Nonparametric Hazard Rate Estimation With Associated Kernels and Minimax Bandwidth Choice

ABSTRACT In this paper, we introduce a general theoretical framework for nonparametric hazard rate estimation using associated kernels, whose shapes depend on the point of estimation. Within this framework, we establish rigorous asymptotic results, including a second‐order expans...

HCV incidence and prevalence trends among people who use drugs in France 2004 to 2023

Abstract Hepatitis C virus (HCV) remains a key public health challenge, particularly among people who use and inject drugs (PWUD, PWID). While direct-acting antivirals (DAA) have revolutionized HCV treatment, meeting the WHO’s 2030 elimination target requires accurate estimation...

Whole‐crop harvestable chicory for the phytoextraction of copper from wine‐growing soils and its use in animal feed

Abstract Background Since 2018, European Union regulations have reduced copper (Cu) doses in viticulture to combat fungal diseases, but Cu continues to accumulate in soils, potentially harming soil organisms. The aim of our study was to reduce the Cu content of soils by means of...

Wavelength-Selective Magneto-Optical Diodes Based on Rare-Earth Chiral Molecular Crystals

Abstract Chiral materials, integrating structural breaking of mirror-symmetry, exhibit physical properties that cannot be observed in centrosymmetric analogues. Among these properties, optical magneto-chiral anisotropy, the nonreciprocal absorption of light shown by chiral magnet...

Reflector‐Free, Highly Confined Love‐Like SAWs Enabled by a Phononic Metasurface for Real‐Time Monitoring of Cell Dynamics

ABSTRACT Surface acoustic wave (SAW) devices are widely used in sensing and biosensing but generally suffer from strong attenuation in liquid environments. Conventional approaches rely on reflectors to reduce these losses, yet these components remain difficult to optimize: limite...

Constructive S4 modal logics with the finite birelational frame property

The logics \(\mathsf {CS4} \) and \(\mathsf {IS4} \) are the two leading intuitionistic variants of the modal logic \(\mathsf {S4} \) . Whether the finite model property holds for each of these logics have been long-standing open problems. In this paper, we resolve the first of t...

MAC-explorer: bridging genome-based taxonomy and an identification tool for the Mycobacterium avium complex

The Mycobacterium avium complex (MAC) comprises genetically close nontuberculous mycobacteria responsible for human and animal infections worldwide. Increasing availability of whole-genome sequencing (WGS) data offers new opportunities for genomic surveillance and lineage trackin...

Boron Monofluoride Complexes Bearing π‐Expanded Coumarin Subunits: Facile Synthesis, Crystal Structure, and Solid‐State Enhanced Emission

Boron-containing compounds have received special interest over the last few years owing to their favorable photophysical characteristics, stimulating their use as fluorescent sensors, in bioimaging and mechanofluorochromic materials. However, their synthesis is often time-consumi...

Early onset of the hot circumgalactic medium around Milky Way galaxies

Abstract Hot coronae are key regulators in Milky Way (MW)-type galaxy formation and are thought to emerge once a galaxy’s dark matter halo crosses a critical mass threshold, Mvir ~ 1012 M⊙, so that accretion shocks can heat infalling gas to virial temperatures, Tvir. Here we inve...

A Complex‐Frequency Framework for Kerker Unidirectionality in Photonic Resonators

ABSTRACT Electromagnetic scattering exhibits various anomalous behaviors, such as forward or backward scattering effects known as the Kerker conditions. These anomalies appear in non‐Hermitian photonic resonators and are mathematically described by operators with complex eigenfre...

Limited global awareness of invasive alien species and little support for their management

Invasive alien species (IAS) are one of the main drivers of global change and can cause a wide range of negative ecological and social impacts. Addressing these impacts requires management actions, which can fail to be effective when not supported by the public. Here, we conducte...

Tuning the Architecture of High-Density Bottlebrush Block Copolymers to Control Their Photonic Properties

Abstract The backbone rigidity of bottlebrush block copolymers (BBCPs) induced by the dense branches distributed along their polymeric backbones has made them materials of interest for fast self-assembly of photonic materials. Today, the rigidity of BBCPs is limited by the maximu...

Transcriptional responses of Solanum lycopersicum to three distinct parasites reveal host hubs and networks underlying parasitic successes

Abstract Crops face attacks from a wide range of pathogens and pests that deploy various parasitic strategies. All aggressors must manipulate major plant functions, such as immune signaling, hormone pathways, metabolism, and development, to successfully establish themselves and c...

Beam-offset thermoreflectance with Bayesian optimization to measure the anisotropic thermal properties of semiconductor superlattices

The directional nature of heat conduction in semiconductor superlattices—marked by significant differences between in-plane and cross-plane pathways—poses substantial challenges for precise thermal property assessment. Conventional frequency-domain thermoreflectance (FDTR) techni...

A phosphoinositide and RAB switch controls early macropinocytosis

Macropinocytosis is a non-selective endocytic process by which cells take up large amounts of extracellular fluid into giant vesicles known as macropinosomes. This mechanism is used by immune cells to sample the surroundings for antigens and can be exploited by cancer cells for n...

Simulation analysis of self-excited oscillating water jet with petal-shaped nozzle under confining pressure

The self-excited oscillating water jet is widely used in ocean engineering. Its effectiveness stems from the impact of cavitation collapse driven by periodic pressure pulsations. This study investigated the flow field evolution and vortex stretching mechanisms of self-excited osc...

Ground-motion dataset for shallow earthquakes in Colombia

Abstract. The tectonics of Colombia is characterised by the interaction of multiple oceanic plates subducting beneath the continent, generating active transpressional deformation and a wide range of subduction-related and crustal earthquakes. We present a flatfile containing grou...

PI3Kδ is selectively inhibited by roginolisib by stabilizing the C-terminal helix kα12

Abstract Phosphoinositide 3-kinases (PI3Ks) are major regulators of cell growth, proliferation and signalling, constituting key therapeutic targets in cancer, inflammation, and other diseases. Individual class I PI3K isoforms control key cellular functions, imposing the need to g...