Centre National de la Recherche Scientifique

Routing to the seizure in postoperative human glioma cortex: spatio-temporal uncoupling between slow and fast extracellular neuronal activities

Abstract Background Diffuse gliomas are frequently associated with epilepsy, particularly in low-grade variants. Seizures are key events to be considered in glioma management, including during surgery. Optimizing resection of epileptic areas may affect not only postoperative epil...

The petal identity gene PhDEF has a major binding and regulatory action in the epidermis

ABSTRACT In flowering plants, floral organ identity is specified by the combinatorial action of homeotic genes. While the role of these genes in the early specification of organ identity is well established, their late function throughout floral organ development and in specific...

Micromechanical Insights Into the Cyclic Behavior of Fault‐Valve Systems

Abstract Cyclic fluid pressurization can promote repeated fault reactivation and transient permeability changes, a behavior often discussed within the fault‐valve concept in which faults alternate between acting as hydraulic barriers and conduits. To investigate the micromechanic...

Isolating the exposomic impact of acute war and displacement within chronic crisis using multimodal, AI-enabled phenotyping

Abstract Wars often unfold within contexts of prolonged instability, yet little is known about how acute conflicts interact with cumulative exposomic adversity to shape mental health processes. Here we studied clinical and subclinical symptoms in a Lebanese sample across three gr...

Hominin behavior, strategies, and environmental conditions in Southern Europe (Marine Isotope Stage 17–15): The 100-ka sequence of Notarchirico (Italy, 700–600 ka)

The Notarchirico sequence comprises a continuous 100-ka-long record of phases of hominin occupation between Marine Isotope Stage 17 and Marine Isotope Stage 15, revealing remarkable technological stability alongside some innovations. We analyzed core technology, raw material prov...

Beyond Beauty: Microalgae and Cyanobacteria as Next-Generation Platforms for Functional Dermocosmetics, Cutaneous Delivery, and Skin Health

Microalgae and cyanobacteria are valuable sources of bioactive ingredients and innovative biological systems for skin applications. Their metabolites include exopolysaccharides (EPS), mycosporine-like amino acids (MAAs), carotenoids, phycobiliproteins, peptides and lipopeptides,...

The Evolution of Low-ionization Electron Densities in Galaxies across Cosmic Epochs

Abstract We investigate the low-ionization electron density in the interstellar medium (ISM) of galaxies across 0 < z < 8, derived with the [O ii ] λλ 3727, 3730 and [S ii ] λλ 6718, 6733 doublets, using both deep JWST/NIRCam/grism and NIRSpec/MSA spectroscopy. Along with ancilla...

A Dichalcogenide-Protected Pt@Au12@Ag8 Nanocluster

Abstract Precise control over the location of heterometal atoms in alloy nanoclusters is essential for understanding how metal distribution governs superatomic structure and properties. Herein we show that PtAg20[S2P(OPr)2]12 (PtAg20) can serve as a structurally defined precursor...

Modeling of gas-water transport in the porous transport layer of a proton exchange membrane electrolyzer

In this work, the mechanism of gas invasion into a saturated thin porous medium, specifically the Porous Transport Layer used in a Proton Exchange Membrane electrolyzer, is investigated. The phase-field model based on the Cahn-Hilliard theory is employed to capture the dynamics o...

Magnetohydrodynamic drag on an oscillating sphere in a rotating spherical cavity

Oscillating-sphere drag is a classical fluid-mechanics problem, yet no theory simultaneously accounts for confinement, rotation, viscosity and magnetic fields. We consider a conducting sphere undergoing translational oscillations inside a rotating spherical cavity, modelling conf...

Reimpregnation of Disordered Mesopores by Ionic Liquids

Abstract The reimpregnation, i.e., replacement of the soft-templating ionic liquid (IL, BMIM-TFSI) that forms the porosity during the synthesis of disordered mesoporous silica-based (ionosilica) materials, has been studied by an original combination of small-angle X-ray scatterin...

Questioning the G2 phase in the budding yeast cell cycle with a qualitative and possibilistic model

Abstract The budding yeast S. cerevisiae , a foundational model for cell cycle studies, exhibits a complex phase organisation (G1, S, G2/M) governed by checkpoints ensuring faithful cellular inheritance. However, the existence of a distinct G2 phase in yeast remains debated, with...

Quantum roots for Kac–Moody root systems and finiteness properties of the Kac–Moody affinized Bruhat order

The notion of quantum root comes up in the study of the quantum cohomology of generalized flag varieties, quantum Bruhat graphs or in the study of the affinized Bruhat order on an affinized Weyl semi-group. In this paper, we provide a complete classification of quantum roots asso...

Integrating Drug Physicochemistry and Hfq-Dependent Regulation of Ciprofloxacin Accumulation in Escherichia coli

Ciprofloxacin (CIP), an amphoteric fluoroquinolone, undergoes pH-dependent changes in protonation state that influence membrane permeability and intracellular accumulation. Here, we investigated how drug physicochemistry and bacterial regulatory pathways jointly determine CIP acc...

Half-Flips are 5-Avoidable

A word contains a half-flip if it contains non-empty factors [Formula: see text] and [Formula: see text] where [Formula: see text]. Fici reports a non-constructive proof of the existence of an infinite word over a finite alphabet avoiding half-flips and asks for the size of the s...

Multiscale Methods for Wave Propagation in Materials with Sign-Changing Coefficients

Abstract. From a mathematical perspective, the extraordinary properties of metamaterials are often reflected in the coefficients of the governing partial differential equations. These coefficients may fall outside the assumptions of classical theory, particularly when the effecti...

Airflows redefine the cost of aerial transport in the wild

Fuel economy matters to both animals and machines, as the cost of transport can determine where, when, and how far locomotion is possible. However, established estimates of these values for animal flight come from laboratories and treat the atmosphere as constant, even though fre...

Multi-predator feeding aggregations in pelagic waters

Abstract Multi-predator feeding aggregations (MPFAs) are temporary co-occurrences of several species of predators simultaneously exploiting the same prey resource. Pelagic waters are home to the largest and most diverse MPFAs on the planet, however, our knowledge of the mechanism...

Structural basis for size-selective perception of chitin in plants

Plants detect microbes through pattern recognition receptors that perceive conserved microbial surface motifs known as microbe-associated molecular patterns (MAMPs). Lysin motif (LysM) receptors recognize and mediate downstream responses to chitinous MAMPs. In this study, we eluc...

Deciphering Aggregation-Induced Tunable Circular Dichroism of AuBP@Ag and AuBP@Au Chiral Core–Shell Plasmonic Nanoparticles

Abstract Plasmonic nanoparticles exhibiting strong and tunable chiroptical signals have been drawing much interest recently due to their potential vast applications. A few years ago, it was shown that seed-mediated metal growth can be harnessed to make single nanoparticles intrin...