Centre National de la Recherche Scientifique

Longitudinal progression, metrics, age-dependence, and modifiers of ataxia severity in SCA27B: a multicentre study of 219 patients

Background Spinocerebellar Ataxia 27B (SCA27B) is a novel, frequent and likely treatable late-onset autosomal-dominant ataxia caused by GAA repeat-expansions in FGF14 . For understanding disease evolution and imminent trial planning, metrics of the most widely used clinical outco...

HighlyTransparent Layer-by-Layer Nanoassembled MulticomponentFilms of TiO2 and Graphene for Increased PhotocatalyticPerformance

Abstract Here, we report novel highly transparent and photoactive multicomponent films for enhanced photocatalytic applications. Some films are based on intimately interfaced TiO2 nanoparticles and few-layer graphene (FLG) assembled through an environmentally friendly aqueous lay...

Influenceof Anti-Agglomerants and Water Cut on FlowAssurance and CO2 Capture in a Model Water-in-Oil Systemfor Maritime Applications

Abstract This study investigated the effects of antiagglomerant (AA) concentration and water cut (WC) on flow assurance within a gas hydrate-based CO2 capture and transport using a model water-in-oil (W/O) system for maritime applications. Phase equilibrium measurements revealed...

Toward Climate-Responsive Ocean–Terrestrial Biorefineries: Integrating Algae and Agricultural Residues for Circular Bioeconomies

Abstract This paper evaluates climate-responsive biorefineries that integrate pelagic Sargassum with agricultural residues to advance circular bioeconomies. Building on scientific priorities emphasized at the 2025 One Ocean Science Congress and emerging policy directions from the...

Unraveling HBV Life Cycle by Fluorescent Microscopy Imaging

The hepatitis B virus (HBV) is a worldwide hepatotropic virus despite the availability of a highly effective vaccine. Currently, the most efficacious treatment against HBV infection is the use of interferon and nucleos(t)ide analogs, which effectively suppress viral replication b...

Unleash $Q$! cohomology, localization, and interpolation in Parisi-Sourlas supersymmetry

Parisi—Sourlas supersymmetric models are known to undergo dimensional reduction; that is, their physics is captured by models in two fewer dimensions. In this work, we revisit dimensional reduction, providing new arguments and reformulating existing proofs in terms of the cohomol...

Morphological and Size‐Dependent Enrichment of Endotoxins in Coastal Spray Aerosols: Implications for Regional Respiratory Health Risks

Abstract Sea spray aerosols (SSA) transport bioactive substances that affect the Earth's environmental and climate system. We investigated the enrichment of endotoxins (LPS), characterized their influence on the SSA morphologies, and evaluated the respiratory tract deposition. LP...

Mapping structural heterogeneity in three-dimensional biophotonic gyroid networks using position-resolved small-angle X-ray scattering

Abstract The wings of select Papilionid and Lycaenid butterflies contain a three-dimensional gyroid network of a solid cuticle phase in air. In butterfly scales, gyroid networks are optically interesting, as they create the green colour observed in the wings of these butterflies....

Topological robustness of optical skyrmions through a real-world free-space link

Structured light offers a promising solution for the increasing data demands of modern optical networks, opening up degrees of freedom that can be leveraged for greater channel capacity and more bits per photon. However, its implementation is hindered by real-world distortions, f...

Widespread thermophilization but weak link to climate warming in Europe’s summit plant communities

Abstract Recent changes in alpine vegetation are often attributed to climate warming, particularly community composition shifts towards more warmth-associated species, or thermophilization. Here we assess the link between thermophilization and warming across 53 European mountain...

Occurrence and controls of ~ 1 Hz waves in Mercury’s magnetosphere: insights from MESSENGER observations

<title>Abstract</title> Mercury’s magnetosphere is highly dynamic, with processes occurring on much shorter spatial and temporal scales than at Earth due to its weak magnetic field and proximity to the Sun. Wave-driven transport of energy and momentum is a key manifestation of th...

Questioning the Evidence for Host-Symbiont Codiversification in Mycorrhizal Symbioses

Abstract The vast majority of plants form mycorrhizal symbioses. The ecological importance of these mutualistic interactions has sparked interest in their long evolutionary history. By examining interaction networks and phylogenetic trees, several studies have suggested that plan...

Critical neuronal avalanches arise from excitation-inhibition balanced spontaneous activity

Neuronal avalanches are sequences of neural activations exhibiting scale-invariant statistics, indicative of critical dynamics. Theoretical studies proposed that the balance between excitation (E) and inhibition (I), along with neuromodulation, are key factors influencing this cr...

Iron Isotopes Reveal Fe Export Driven by Change of Tropical Weathering Regime

Abstract Unraveling paleoenvironmental signals recorded in laterites is crucial for quantifying weathering‐driven elemental fluxes at the Earth's surface. New stable iron isotope data (δ 56 Fe), combined with (U‐Th)/He ages in Fe‐oxides from a ferruginous duricrust from French Gu...

Genetic variability and population structure within the Anopheles tessellatus complex (Theobald, 1901) in Indonesia using ITS2 nuclear and COI, COII mitochondrial sequences

Abstract Some Anopheles species that act as malaria vectors are members of species complexes, a concept whereby sibling species cannot be differentiated solely on the basis of morphological characters. Therefore, species complexes represent a major problem in malaria vector contr...

Optimal Vaccination Strategies for a Heterogeneous SIS Model

Abstract. We study in a general mathematical framework the optimal allocation of vaccine in an heterogeneous population. We cast the problem of optimal vaccination as a biobjective minimization problem [Formula: see text], where [Formula: see text] and [Formula: see text] stand,...

An Alternative Approach to Compute the Likelihood for the DAISIE (Dynamic Assembly of Island Biota Through Speciation, Immigration, and Extinction) Model

Abstract Understanding island biodiversity requires studying the processes driving its assembly and examining how these processes vary over time, across lineages, and across different islands. The DAISIE (Dynamic Assembly of Island biota through Speciation, Immigration, and Extin...

Neutron elastic scattering at $$\varvec{30.8}$$ MeV on $$\varvec{^{\text {nat}}\textrm{Ce}}$$

Abstract Elastic scattering of fast neutrons at an incident energy of 30.8 MeV on a natural cerium target was measured during an experiment conducted at the Neutrons For Science facility at GANIL-SPIRAL2. This is the first measurement on cerium using incident neutron energy above...

GRB 260310A / SN 2026fgk: A Multi-Wavelength Study of a Nearby Underluminous Long GRB and SN with a Complex Afterglow

Abstract We present a comprehensive multi-wavelength study of GRB 260310A / SN 2026fgk, a nearby (z = 0.153), long-duration gamma-ray burst (GRB) with an exceptionally underluminous prompt γ-ray emission and a Comptonized spectrum. The burst occurred at the edge of a blue host ga...

The extreme diversity of retinal amacrine cells has deep evolutionary roots

Amacrine cells (ACs) comprise a heterogeneous class of inhibitory neurons in the vertebrate retina, exhibiting morphological and functional complexity rivaling that of cortical interneurons. Here, we integrate single-cell and single-nucleus transcriptomic atlases from 24 vertebra...