Centre National de la Recherche Scientifique

Evaluating age-related differences in motor imagery in children aged 5 to 8: feasibility and task-specific modulation

Motor imagery (MI), the mental simulation of movement without execution, provides a behavioural tool to evaluate sensorimotor representations. However, its characterisation in young children remains debated. This study investigated age-related differences in MI across early prima...

Collective adsorption of pheromones at the water–air interface

Abstract Understanding the phase behaviour of pheromones and other messaging molecules remains a significant and largely unexplored challenge, even though it plays a central role in chemical communication. Here, we present all-atom molecular dynamics simulations to investigate th...

Deciphering coccolith formation: advanced microscopy insights from the biomineralization of Gephyrocapsa huxleyi

Abstract Coccolithophores are unicellular marine phytoplankton that produce complex and intricately shaped mineralized scales called coccoliths. Coccoliths are produced in an intracellular vesicle where crystal nucleation occurs, from which several individual calcite units develo...

Neutralization titers reveal the structure of polyclonal antibody responses

The composition of a polyclonal antibody response is hard to measure experimentally but contains vital information about the robustness of immunity. Here, we argue that the statistics of neutralization titers alone can be used to make quantitative predictions about the compositio...

Clinical and ecological significance of bacterial dormancy in human pathogens

SUMMARY Bacteria can enter a transient state of reduced metabolic activity to survive temporary unfavorable conditions. This phenomenon, sometimes referred to as dormancy, growth arrest, or quiescence, enables pathogen survival inside and outside of their host, with major clinica...

Geometry-enforced topological chiral fermions in amorphous chiral metals

Since the prediction and observation of topological Weyl semimetals (chiral TSMs), there have been enormous efforts to characterize further condensed matter realizations of chiral fermions. These efforts were dramatically accelerated by the subsequent discovery of a profound link...

Improved estimation of net ecosystem CO 2 exchange over North America using LSTM-based flux upscaling (2001–2021)

Accurate estimation of regional-scale terrestrial carbon budgets is of great importance but remains challenging. With particular advantages, the Long Short-Term Memory (LSTM) network method shows potential for improving regional carbon budget upscaling estimations. Here, using LS...

Sensitive reverse transcription-digital droplet PCR-based discrimination of hepatitis delta virus RNAs reveals differential effects of interferon-α on viral RNA species

Hepatitis delta virus (HDV) replication relies on the production of distinct viral RNA species, including genomic (HDV-G), antigenomic (HDV-AG) and mRNAs (HDV mRNAs), which differ in abundance and function. However, the lack of sensitive and quantitative approaches allowing their...

Assessment of infection prevention practices in office-based surgery: a multicentre regional audit

Abstract Background Office-based surgery (OBS) is increasingly used due to organizational constraints and perceived benefits. However, data on infection prevention and control (IPC) practices in OBS settings remain limited. This study aimed to assess the conditions in which OBS a...

Memory on ice: spatial memory is retained over a 9-month hibernation period in Columbian ground squirrels

Abstract Memory allows animals to utilize ecologically relevant information, yet whether it endures through prolonged metabolic shutdown is poorly understood. We tested spatial memory retention in a long-term, free-living hibernator, the Columbian ground squirrel (Urocitellus col...

Concurrent synchronization and covariation in upper extremity joint angles during a reciprocal aiming task

Abstract The ecological-dynamical approach holds that movement is self-organized, implying a circular causality between the kinematics of the end-effector and the coordination of degrees of freedom (DOF) into synergies. Yet, how this circular causality manifests itself in redunda...

Experimental impact study on a micro-grid project in rural Madagascar: The Café Lumière project

This paper evaluates the impact of a pilot innovative project aiming at promoting a replicable model to create access to distributed electricity in rural areas where grid extension is economically infeasible. The project proposes building solar-powered micro-grids to provide affo...

Long-term preservation of early-formed silicate reservoirs in the deep mantle: New insight from 146Sm-142Nd systematics in Hawaiian basalts

Short-lived radiogenic isotope systems provide unique constraints on the preservation of early-formed reservoirs in Earth's mantle. We present the largest high-precision μ 142 Nd dataset for a single hotspot, comprising 55 analyses of 29 shield-stage tholeiitic basalts from the H...

Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature

Positional vertigo is a frequent complaint in otology and vestibular physiotherapy, arising from functional or structural causes affecting the peripheral or central vestibular systems. Although benign paroxysmal positional vertigo (BPPV) is the most common form, other etiologies...

A cytidine deaminase biodegrader sensitises multiple cancer types to deoxycytidine analogue-based chemotherapies

Abstract Deoxycytidine (dC) analogues are widely used to treat solid tumours and blood cancers. However, their clinical efficacy is often limited by resistance mediated by cytidine deaminase (CDA), which converts these drugs into inactive metabolites. Existing CDA inhibitors have...

Super Bloom: Fast and Precise Filter for Streaming k -Mer Queries

Approximate membership query structures are used throughout sequence bioinformatics, from read screening and metagenomic classification to assembly, indexing, and error correction. Among them, Bloom filters remain the default choice. They are not the most efficient structures in...

Genomic global epidemiology and evolution of Escherichia coli ST131 clade A

During the 2010s, Escherichia coli ST131 clade A tested sensitive to most antibiotics. In the 2020s, Europe experienced outbreaks of fluoroquinolone-resistant ST131-A that contained CTX-M β-lactamases and OXA-48-like carbapenemases. We investigated the acquisition of different an...

Distributed Phase-Shedding: A Scalable Solution for Automotive Microprocessor Power Supplies

The increasing computing power required by autonomous vehicles imposes stringent requirements on automotive microprocessor power supplies in terms of efficiency, scalability, and fault tolerance. Conventional phase-shedding strategies for multiphase converters rely on centralized...

What Does It Mean for a Star-Shaped 3D Scatterer to Be Small in the Time Domain?

Abstract. In the frequency domain wave scattering problems, obstacles can be effectively replaced by point scatterers as soon as the wavelength of the incident wave exceeds significantly their diameter. The situation is less clear in the time domain, where recent works suggest th...

Embryos resolve the enigmatic origin of the theropod wishbone

The origin of the avian wishbone (furcula)—present since theropod dinosaurs—remains unsolved. Its homology is still debated, with competing hypotheses proposing derivation from the clavicles, the interclavicle, or both. To obtain comparative developmental evidence, we studied oss...