Research works

Combined medial patellofemoral ligament reconstruction and distal femoral derotation osteotomy in recurrent patellar dislocation with Jumping J sign

Recurrent patellar dislocation (RPD) is commonly associated with patellar maltracking, and the Jumping J sign may indicate a severe instability phenotype. The optimal surgical strategy for patients with this sign remains unclear. The purpose of this study was to compare clinical...

Candidate neurobiological pathways linking physical exercise to cognition in Parkinson’s disease: a hypothesis-generating translational framework

Cognitive impairment is a major nonmotor symptom of Parkinson's disease (PD), yet effective strategies for preserving cognitive function remain limited. Although physical exercise may confer cognitive benefits, the biological pathways linking exercise to cognition in PD remain in...

GM-DualTransAML++: A Multi-Source Graph–Transformer Framework with Statistical Risk Mining and Typology Supervision for Anti-Money Laundering Detection

Anti-Money Laundering (AML) has become an increasingly critical challenge for financial institutions because of the rapid growth of digital transactions, sophisticated laundering strategies, and the extreme imbalance between legitimate and suspicious activities. Conventional rule...

Fabrication of Conformal FSS Radome Based on MOPSO inverse design and mask spraying

Conformal electromagnetic structures play an important role in modern aerospace and communication systems by combining spatial filtering capability with aerodynamic compatibility. However, transferring planar frequency-selective surfaces (FSSs) onto complex curved profiles can in...

Complementarity of Empirical, Analytical and Numerical Techniques for Assessing the Stability of a Natural Cave System in the Coastal Cliffs of Las Grutas (Río Negro, Argentina)

Coastal caves developed in weak and heterogeneous cliffs constitute complex geomechanical systems in which lithological variability, structural discontinuities, groundwater seepage and marine erosion interact. Their stability assessment is particularly challenging in urbanised co...

Cell-resolved spatial mapping of antibody-drug conjugate targets in breast cancer

Background Antibody-drug conjugate (ADC) activity and target-dependent on-target/off-tumor toxicity depends in part on which cells express the target antigen, a feature that bulk assays cannot resolve. Methods We analyzed a publicly available whole-transcriptome CosMx breast tumo...

Antimonate reduction and immobilization driven by pyrite and woodchips-based abiotic and biotic processes

Antimony (Sb) pollution in aquatic environments poses severe threats to ecological safety and human health due to its high toxicity. Four reaction systems were constructed in this study, including a pyrite abiotic reactor (PAR), a pyrite-woodchips abiotic reactor (PWAR), a pyrite...

Epigenetic-Targeting Regimens vs. Conventional Chemotherapy in Relapsed/Refractory PTCL: A Meta-Analysis

PurposeRelapsed/refractory peripheral T-cell lymphoma (R/R PTCL) lacks a uniform salvage standard and outcomes with conventional chemotherapy (CC) remain suboptimal.This meta-analysis compared epigenetic-containing regimens (Epi-Rx) and CC in R/R PTCL. Materials and MethodsWe sea...

Prevalence, facilitators and barriers to patients’ decisions on root canal treatment in public dental clinics in central Malaysia: a multicentre mixed-methods study

Root canal treatment (RCT) is a key strategy for preserving natural teeth, yet the prevalence and factors influencing RCT uptake in Malaysia are still sparse in the literature. This study aimed to determine the prevalence of RCT uptake and identify facilitators and barriers influ...

Development and temporal validation of a nomogram for predicting same-day discharge after hysteroscopic myomectomy: a retrospective cohort study

This study aimed to identify factors associated with completion of same-day discharge (SDD) after hysteroscopic myomectomy in a day-surgery setting, to develop and temporally validate a prediction model, and to determine when reliable prediction becomes possible along the periope...

High-performance brain tumor classification via transfer learning with fully fine-tuned and modified CNN architectures

Accurate and timely brain tumor diagnosis remains challenging due to the limitations of manual MRI interpretation. This study introduces a transfer learning framework using six fully fine–tuned and modified CNN architectures DenseNet169, InceptionV3, Xception, ResNet50, Inception...

Understanding ongoing processes of terrestrial mud diapirism through absolute gravimetry and geodetic approaches in SW Taiwan: implications for geological hazards

Mud diapirs and mud volcanoes are widespread geological features driven by subsurface seepage or extrusion of liquid and over-pressured mudstone. These formations pose significant hazards due to the emission of flammable gases, formation of mudflows, and release of atmospheric me...

Association between bedside oral health status and severe acute respiratory syndrome in hospitalized adults: a cross-sectional study

Hospitalized patients may experience oral health deterioration, particularly during acute respiratory illness. This study investigated the association between bedside oral health status and severe acute respiratory syndrome (SARS) in hospitalized adults. This cross-sectional stud...

Fuel cell combined cooling, heating and power system: Energy management strategy and multi-objective optimization configuration considering economy and energy efficiency

This study investigates the fuel cell combined cooling, heating and power (FC-CCHP) system, and proposes a novel Following Coordinated Thermal-Electric Load (FCTEL) strategy to overcome the multi-load mismatching defects of conventional FTL and FEL strategies. Simulation results...

Repeat pulmonary resection for multiple primary lung cancer: perioperative safety and long-term oncological outcomes

With widespread low-dose CT screening, multiple primary lung cancer (MPLC) diagnoses have markedly increased. Surgical resection remains the preferred treatment; however, repeat pulmonary resection is technically demanding due to pleural adhesions and altered anatomy from prior s...

Rethinking primary–palliative care collaboration: insights from a mixed-methods study in a spanish region

Both specialist- and primary-level palliative care services are needed if high levels of access to palliative care are to be achieved. The Alava province in the Autonomous Community of Spain’s Basque Country is undertaking a quality improvement initiative to optimize collaboratio...

Why support for net-zero technologies can be politically vulnerable: Evidence from Celtic Sea floating offshore wind

Support for net-zero technologies can be broad yet remain politically vulnerable. Actors may converge on the same technology through distinct problem diagnoses without forming a resilient coalition. This Perspectives article examines this proposition through Celtic Sea floating o...

Process intensification of indigenous algal-bacterial consortia by ARTP-mutagenized Chlorella for aquaculture wastewater treatment and resource recovery

Achieving stable algal-bacterial treatment in real aquaculture wastewater remains difficult because indigenous microbiota are often viewed as uncontrollable background communities rather than functional components with regulatory potential. In this study, atmospheric and room-tem...

The effect of pulsating liquid sodium coolant inlets on flow structures and thermal mixing in a T-junction

Mixing of two pipe streams at different temperatures features in the secondary circuit of compact sodium-cooled fast reactors. This study presents the numerical simulation of flow features and mixing characteristics in the T-junction with the inlets subjected to co-pulsating and...

Integrative chemometric profiling of biochemical composition, fatty acids, minerals, organic acids, and carbohydrates in wild olive (Olea europaea L. subsp. oleaster) genotypes for quality-oriented selection

This study aimed to comprehensively evaluate the compositional diversity of wild olive ( Olea europaea L. subsp. oleaster ) genotypes through an integrated analysis of biochemical traits, fatty acid composition, mineral elements, organic acids, and carbohydrates, and to identify...