Research works

Associations of mental health with subsequent weight development during a 4-year follow-up in adolescence

Abstract Background Although obesity and mental health problems represent two of the most pressing public health challenges, their developmental interplay remains insufficiently understood. Thus, we examined how depressive and anxiety symptoms, self-esteem, and psychological resi...

Prevalence and Predictors of Mechanical Restraint in Involuntary Patients in an Open-Door Inpatient Psychiatric Unit

Abstract Purpose Mechanical restraint (MR) remains one of the most controversial interventions in psychiatry, particularly in involuntarily admitted patients. This study examined the prevalence and clinical predictors of MR in an open-door psychiatric unit in Spain, a context whe...

Refining genetic circuit design for enhanced type II polyketide biosynthesis in Escherichia coli

Polyketides represent a broad class of structurally diverse natural products with potent antibacterial and anticancer activities. Type II polyketide synthases (T2PKS) are multi-subunit complexes responsible for condensing acylated intermediates, including acetyl-CoA and malonyl-C...

Towards whole plastome phylogeography: resolving small genetic distances among European Arnica montana L. with the PlastidPipeline

<title>Abstract</title> <italic>Arnica montana</italic> L. is a medicinal plant endemic to Europe and declining in large parts of its range. Low sequence diversity in genetic marker regions caused biogeographic patterns and the phylogenetic relationship between <italic>A. montana...

Robotic-assisted versus conventional laparoscopic rectopexy for rectal prolapse: a single-center cohort study

<title>Abstract</title> Background Minimally invasive techniques have become the standard of care for treating rectal prolapse through a transabdominal approach. However, there is limited data comparing the laparoscopic and robotic approaches in terms of long-term recurrence and...

RobustCell: a model attack-defense framework for robust transcriptomic data analysis

Abstract Computational methods should be accurate and robust for tasks in biology and medicine, especially when facing different types of attacks, defined as perturbations of benign data that can cause a significant drop in method performance. Therefore, there is a need for robus...

Fast, unconditional reset and leakage reduction in fixed-frequency transmon qubits

Abstract On-demand qubit-state initialization is a prerequisite for quantum computation. We demonstrate such a protocol in a device consisting of fixed-frequency transmon qubits pair-wise coupled via tunable couplers — an architecture that is also compatible with the surface code...

Kernel smoothing operators on thick open domains

We study the convergence properties of a general family of normalized Markovian kernels on a domain $$\Omega$$ in the Euclidean space. Based on the notion of a thick set we show that a local Hardy-Littlewood inequality holds in $$L^p(\Omega)$$ , $$p \in (1, \infty]$$ when $$\Omeg...

Robust joint estimation of galaxy redshift and spectral templates using online dictionary learning

We present a novel approach to analyzing astronomical spectral survey data using our non-linear extension of an online dictionary learning algorithm. Current and upcoming surveys such as SPHEREx will use spectral data to build a 3D map of the universe by estimating the redshifts...

Robust Integral Consensus Control of Multi‐Agent Networks Perturbed by Matched and Unmatched Disturbances: The Case of Directed Graphs

ABSTRACT This work presents a new method to design consensus controllers for perturbed double integrator systems whose interconnection is described by a directed graph containing a rooted spanning tree. We propose new robust controllers to solve the consensus and synchronization...

Finite-R Poisson Transfer for Mellin-Neutralized Incomplete Eisenstein Observables I: Effective Aggregate Sarnak–Zhao Identification and Logarithmic Persistence

This paper provides the technical proof carrier for the finite-$R$ reconstruction of harmonic quantum variance for a Mellin-neutralized moving family of incomplete Eisenstein observables on the modular surface. Starting from the exact parity-complete Kuznetsov decomposition $$S_R...

A Conditional Reduction of the Riemann Hypothesis to Even Dominance of the Weil Quadratic Form

This paper presents a conditional reduction and diagnostic programme toward the Riemann Hypothesis via even dominance of the Weil quadratic form. It extracts the proof-relevant chain from a three-part Landscape series while making the remaining mathematical gap explicit. (i) Exte...

The Artian Keystone Audit

Which QTT numbers are pure, anchored, keystone-dependent, or structural? The Keystone Audit classifies every headline result before judging its numerical landing. Its paper-native master split remains \[ \boxed{ \mathcal R = \mathcal R_{\rm U}\sqcup \mathcal R_{\rm A}\sqcup \math...

From Landscape to Atlas: Multi-Route Cartography of an Ongoing Expedition Toward the Riemann Hypothesis

This record is the five-part Landscape/Atlas and audit-trail series for a multi-route investigation toward the Riemann Hypothesis. It documents foundations, obstruction analysis, route failures, computer-assisted diagnostics, spectral route design, and cross-route synthesis. The...

Estimating genetic correlation jointly using individual-level and summary-level GWAS data

Abstract With the increasing accessibility of individual-level data from genome wide association studies, it is now common for researchers to have individual-level data of some traits in one specific population. For some traits, we can only access public released summary-level da...

Mobility, variety, and community in popular Nanyang entertainment from the 1930s to the 1970s

This essay showcases nine photographs and images from various sources, including the National University of Singapore (NUS) Libraries Special Collections, the National Archives of Singapore, and th...

Vibrational power spectra as a tool to benchmark universal machine-learning interatomic potentials for molecular systems: the OMOL-1k-MD data set

Abstract We present OMOL-1k-MD, a new dataset for the benchmark and training of universal machine-learning interatomic potentials (uMLIPs). It contains three independent ab initio molecular dynamics (AIMD) trajectories of 10 ps each for 1000 arbitrarily chosen neutral closed shel...

Developing and validating the Spanish version of the large language models dependency scale (LLM-D12-SP)

<title>Abstract</title> There is a growing need for reliable and culturally validated instruments to assess psychological dependency on large language models (LLMs), particularly as LLMs are increasingly used for task execution, decision-making, and communication in organizationa...

Walrus population-specific marine reservoir offsets (ΔR) for calibration of radiocarbon dates: Implications for Arctic chronologies and medieval trade

Walruses have long played a vital role in Arctic subsistence and commercial economies, yet accurate radiocarbon dating of walrus-derived archaeological materials is complicated by regional variation in marine reservoir effects. This study presents new ΔR values derived from 31 ne...

Trajectories of physical activity and screen media use in toddlers and related parenting practices: Child and Mother Physical Activity Study (CAMPAS)

<title>Abstract</title> <bold>Background:</bold> Physical activity (PA) and screen media use are key behaviors for healthy development in early childhood. This study aimed to investigate 12-month trajectories of PA and screen time among toddlers and examine their associations wit...