Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
126741 work(s)
- Health & MedicineOpen access
Activatable antibodies aim to minimize on-target off-tumor toxicity by suppressing antigen binding through a masking domain that is released only upon encountering a tumor-associated stimulus. Anti-idiotypic single-domain antibodies (dAbs) raised against the complementarity-deter...
- Engineering & TechnologyOpen access
Electrode configuration is one of the key factors affecting the performance of a Vanadium Redox Flow Battery (VRFB). Therefore, it should be carefully designed in accordance with the operating conditions to achieve optimal system efficiency. In this study, multiple electrode aspe...
- Health & MedicineOpen access
Oral microbiome dysbiosis may contribute to autoimmune disease development, but epidemiological evidence linking oral health and autoimmune disease risk is limited. To evaluate the association between self-reported oral health issues by questionnaire—defined as the presence of pa...
- Health & MedicineOpen access
Cerebral thrombosis and abscess: A child with 2 rare complications of tetralogy of Fallot
Tetralogy of Fallot is the most common cyanotic congenital heart disease. Rare cerebrovascular complications include brain abscess and cerebral thrombosis. Herein, we discuss a case of uncorrected tetralogy of Fallot presenting with cerebral thrombosis and multiple brain abscesse...
- Health & MedicineOpen access
Atherogenic lipid-related risk may not be fully characterized by a single lipid measure. A dual-axis framework combining apolipoprotein B (ApoB), a measure of atherogenic particle number, with the LDL-C to total cholesterol ratio (LDL-C/TC), a derived measure of cholesterol parti...
- Health & MedicineOpen access
Objective Depression affects up to 55% of people with epilepsy (PWE) yet remains systematically underdiagnosed. This study aimed to evaluate the psychometric properties of the Czech versions of the Beck Depression Inventory–II (BDI-II) and Beck Depression Inventory–Fast Screen (B...
- Health & MedicineOpen access
Post-Craniotomy Headache: Current Concepts and Emerging Procedural Therapies
Post-craniotomy headache (PCH) is a common complication following neurosurgery, yet there remains limited consensus regarding the mechanism, classification, and optimal management. This review summarizes the current literature and highlights recent trends in procedural therapies....
- Engineering & TechnologyOpen access
This in vitro study evaluated the color stability of polyetheretherketone (PEEK) and graphene-reinforced polymethyl methacrylate (G-CAM) following direct exposure to a high-concentration in-office bleaching gel. Thirty square-shaped specimens (10 × 10 × 3 mm) were prepared: 15 PE...
- Health & MedicineOpen access
Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune astrocytopathy mediated by aquaporin-4 immunoglobulin G (AQP4-IgG), characterized by recurrent inflammatory events affecting predominantly the optic nerves and spinal cord. Despite the availability of targeted...
- BiologyOpen access
Background Persistent human papillomavirus (HPV) infection is a key driver in cervical cancer, yet the molecular mechanisms linking HPV to immune escape remain incompletely understood. Methods We integrated single-cell RNA sequencing (scRNA-seq), bulk transcriptome, and clinical...
- Society & EconomicsOpen access
The prevalence of online learning has been on the rise around the world. The present study aimed to examine the complex relationship between social anxiety, fear of missing out, academic procrastination, and online learning engagement among 1006 students at B University. Utilizin...
- Society & Economics
An Institutional Ethnographic Study of End-of-Life Home Care for Older Adults in Japan
본 연구는 일본의 지역포괄케어시스템에서 고령자가 생애말기 재택케어를 유지하면서 생애 마지막 장소를 선택하는 과정을 제도적 문화기술지(Institutional Ethnography)로 분석한 연구이다. 일본 고령자의 생애말기 돌봄을 분석한 기존 연구들이 주로 재택임종의 조건이나 ACP의 중요성에 주목해왔다...
- Engineering & TechnologyOpen access
Leveraging ultrasound irradiation and Brønsted–Lewis acid synergy, butyl levulinate (BL), a promising bio-based fuel additive, was synthesized by esterifying levulinic acid (LA) with n -butanol over tin(II)-modified silicotungstic acid supported on activated bentonite (Sn x STA/a...
- Society & EconomicsOpen access
Ontological Pluralism Without Degrees of Being
Contemporary ontological pluralism is largely conducted within a shared quantifier-first settlement in which being is rendered as existence and ontological structure through fundamental quantification. Turner shows that multiple fundamental quantifiers need not collapse under the...
- BiologyOpen access
Accounting for noise improves the generalization of acoustic indices when estimating biodiversity
The use of Passive Acoustic Monitoring (PAM) for estimating biodiversity often entails the use of acoustic indices that summarize the acoustic properties of the recordings. Although acoustic indices have been shown to successfully track biodiversity in limited contexts, the recur...
- Climate & EnvironmentOpen access
Management of the volcanological data: an overview
Volcanological data are inherently diverse and heterogeneous. They originate from a broad spectrum of sources, including field observations, sample analyses, ground-based, airborne and satellite remote sensing instruments, permanent monitoring networks, and temporary field campai...
- Climate & EnvironmentOpen access
In Europe, bare soil is typically exposed only during short time windows and optical sensing by satellite constellations, such as Sentinel-2 and Landsat, therefore commonly relies on aggregates of soil reflectance spectra over extended periods of time. Depending on the length of...
- Health & MedicineOpen access
A limited subset of people living with type 1 diabetes (T1D) is affected by extreme glycemic lability and frequent unpredictable severe hypoglycemia, significantly impairing quality of life and associated with higher morbidity, mortality, and healthcare costs. Islet transplantati...
- Health & MedicineOpen access
Dramatic clinical and radiological improvement in acute hemorrhagic leukoencephalitis: a case report
Acute hemorrhagic leukoencephalitis (AHLE) is a rare, fulminant inflammatory demyelinating disorder considered a severe variant of acute disseminated encephalomyelitis and is associated with high morbidity and mortality, particularly in children. Early diagnosis remains challengi...
- AI & ComputingOpen access
Artificial intelligence (AI) is increasingly shaping how innovation is developed, and new product development (NPD) is an important domain at the centre of this shift, given its data-rich, high-uncertainty contexts. In this paper, we focus on the design and training of AI systems...