Research works

Gut microbiota-driven hippuric acid hydrolysis promotes pancreatic tumorigenesis by suppressing NK cell activity

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, characterized by a lack of effective early detection, profoundly immunosuppressive microenvironment, and poor responsiveness to current therapies. Emerging evidence suggests that gut microbiota a...

The Impact of Isoniazid Preventive Therapy on Tuberculosis Infection and Disease Progression.

BACKGROUND: Tuberculosis (TB) causes major morbidity and mortality among children worldwide. Isoniazid preventive therapy (IPT) protects against progression to TB disease, but its effect on preventing new TB infection remains uncertain. METHODS: We conducted a longitudinal cohort...

Speech Outcomes After Primary Palatoplasty With Intravelar Veloplasty and Extensive Muscle Dissection: A Single-Surgeon Cohort Study

This retrospective single-surgeon cohort study evaluated speech outcomes in 79 children with nonsyndromic cleft palate, with or without cleft lip, who underwent primary palatoplasty with intravelar veloplasty involving extensive palatal muscle dissection, performed by a single su...

The Intergenerational Transmission of Gender Roles in Ecuador

The distribution of time dedicated to unpaid work between men and women is unequal. With the increase in female participation in the labor market, this unequal dynamic is expected to disappear. However, it is still maintained by the socialization of traditional gender norms from...

Spring Cranioplasty for the Fused Lambdoid and Coronal Sutures: Expanding Indications

Abstract Spring cranioplasty, originally developed for sagittal synostosis, has expanded to address selected lambdoid and coronal deformities by applying continuous mechanical distraction to gradually expand the cranium while avoiding the extensive dissection required for open va...

Revocable Infrastructure and Generative Dependency: An Open-Then-Enclose Mechanism

A party contributes a method to a commons and opens the infrastructure required to develop it. Others learn the method, build on it, train teams, and develop extensions, and their trajectories become organized around that infrastructure. The party then closes the infrastructure o...

Mixed volumes of zonoids and the absolute value of the Grassmannian

Abstract Zonoids are Hausdorff limits of zonotopes, while zonotopes are convex polytopes defined as the Minkowski sums of finitely many segments. We present a combinatorial framework that links the study of mixed volumes of zonoids (a topic that has applications in algebraic comb...

Metal Magnetic Memory-Based Electromagnetic Non-Destructive Evaluation of Steel-Core Damage in UHV ACSR Conductors

Internal steel-core damage hidden within aluminum conductor steel-reinforced (ACSR) compression components may threaten the mechanical integrity of ultra-high-voltage transmission lines. This laboratory study evaluates metal magnetic memory testing (MMMT) responses to artificial...

EuroMillions Breakthrough Mining — 1891 Sources, 14339 Leads Extracted — E8 Intelligence Research

Mined 1891 lottery+quantum breakthroughs. Extracted 14339 leads across 13 categories. 12282 high-value leads found. Categories: {"CORRIDOR": 1196, "FORMULA": 1037, "GEOMETRIC": 750, "FORWARD_ATTEMPT": 1262, "QUANTUM": 1476, "TIMING": 216, "CELESTIAL": 1122, "GEMATRIA": 1200, "CON...

A Multi-Strategy Kangaroo Escape Optimization Technique for Global Optimization, Engineering Design, and Near-Infrared Prediction of Praeruptorin Content

The Kangaroo Escape Optimization Technique (KET) combines escape and safe-area searches, but its fixed stage allocation, restricted guidance range, limited refinement of low-ranked individuals, and insufficient use of population-state information can reduce its performance on com...

Perceptions of turnout gear fit and movement restrictions among firefighters of different gender, service type, and measurement status

To understand the factors contributing to ill-fitting gear, this study investigated user perceptions across firefighters of different gender, service type, and pre-sizing measurement status. A total of 345 firefighters (19.8% women, 34.8% volunteer firefighters, and 18.0% not mea...

Fish Assemblages Distinguish Eco-Friendly from Conventional Rice Paddies Through Abundance and Biomass Rather than Diversity

Although rice paddies are agricultural land, they also serve as artificial wetlands that deliver essential ecosystem services. Yet how farming systems affect their fish communities—and which metrics best capture those effects—remains poorly quantified in Asia. We compared fish as...

Reproductive and endocrine responses to short-term safflower seed supplementation in anestrous ewes synchronized with progestagen

Abstract. This study investigated the effects of short-term supplementation with safflower seed, a linoleic-acid-rich oilseed, on reproductive performance and endocrine responses in Hungarian Merino ewes during the non-breeding season. Forty-four clinically healthy multiparous ew...

Phi-Driven Irrational Scaling in 5-Fold Quasicrystals — E8 Intelligence Research

The E8 root system's phi-coupling (φ = (1+√5)/2) embedded in its 240 root vectors enables geometric derivation of ψ = √(2φ), a new irrational scaling factor bridging Sulba Sutras' √2 approximation and Penrose tilings' 5-fold symmetry. This ψ factor, synchronized with 132Hz base f...

Neuromuscular Activation Strategies of the Lower Limb During Maximal Sprinting in Youth Track and Field Athletes: Age-Related Differences and Implications for Talent Identification

Sprint performance improves throughout adolescence as a result of both structural and neuromuscular development. In particular, increases in body height, lower limb length, and muscle volume have been consistently linked to improvements in sprint performance. However, allometric...

Impact of preoperative venovenous extracorporeal membrane oxygenation bridging on postoperative acute kidney injury after lung transplantation

Abstract Venovenous extracorporeal membrane oxygenation (VV-ECMO) bridging to lung transplant has the potential to reduce mortality among patients awaiting transplant. However, there continue to be notable morbidity risks, including acute kidney injury (AKI). This paper seeks to...

Natural variation in LuGnTL modulates the trade-off between plant height and seed size in flax (Linum usitatissimum L.)

Flax is an ancient crop cultivated for both fiber and oil, and it has undergone divergent selection into two distinct morphotypes: semi-dwarf oil flax with large seeds and tall fiber flax with small seeds. However, the genetic architecture underlying the trade-off between plant h...

Dynamic Modeling and Self-Tuning Fuzzy Skyhook Control of a Metro Vehicle with a Flexible Carbody and Semi-Active Suspension

Lightweight metro carbodies may exhibit elastic modes within ride-comfort-relevant frequency bands, limiting semi-active suspension controllers tuned offline for nominal conditions. This study proposes a skyhook-based parameter self-tuning fuzzy control (PSTFC) strategy for later...

From volatile to nonvolatile resistive switching in a ferroelectric second-order memristor

Ferroelectric memristors are promising candidates for neuromorphic computing, yet their practical application is hindered by the trade-off between the volatile synaptic plasticity required for learning and the nonvolatile retention needed for long-term data storage. Here, we demo...

Preoperative anxiety, sleep disturbances and postoperative delirium in cardiac surgery: A scoping review for nursing practice

Preoperative anxiety, sleep disturbances and postoperative delirium are common complications among patients undergoing cardiac surgery and are associated with adverse perioperative outcomes. This scoping review aimed to synthesise evidence on the relationship between these factor...