Research works

Antivirulence Benzothiophenes Inhibit Intracellular Mycobacterium tuberculosis by Targeting the Sensor Histidine Kinase MprB

Abstract Pulmonary tuberculosis remains one of the most prevalent and threatening infectious diseases. Classical anti-tubercular therapy targets essential enzymes of the pathogen Mycobacterium tuberculosis (Mtb), thereby suppressing bacterial growth. However, the emergence of dru...

The Response of Extensive Fungal Infections of the Soles of Feet, Palms, and Nails to Low-Dose Food-Grade Hydrogen Peroxide: A Case Report

Background: Due to its growing resistance to treatment, dermatophytosis remains a major global health challenge. Recent case reports of tinea unguium resolution using low-dose food-grade hydrogen peroxide (FGHP) in two patients with 25- and 52-year histories of the disease sugges...

Exploring the role of sustainable finance in enhancing operational efficiency: evidence from firms listed on the London Stock Exchange

Abstract Sustainable finance improves operational efficiency by directing capital toward environmentally responsible investments that reduce costs, optimize resource use, and enhance long-term productivity, while supporting firms’ transition toward greener, more efficient operati...

Metacognition and pathway dynamics in generative AI supported design thinking: A process-sensitive evaluation with network-based cognitive mapping

Generative AI (GenAI) is embedded in design education, yet little is known about how different tools reshape metacognition and the pathways linking ideas to outcomes. We compare three conditions, ChatGPT-4o, DeepSeek-R1, and a no-AI control, in a virtual reality cultural heritage...

Ayurvedic management of trigeminal neuralgia: A case report

Trigeminal neuralgia (TN) is a chronic neuropathic pain disorder characterized by recurrent, electric shock-like facial pain, and conventional treatments often provide inadequate relief, especially in elderly patients. A 75-year-old female with refractory TN was managed through a...

Navigating Disrespect in the Classroom: Intersectionality Pedagogy as Humanizing Praxis for Black Women Faculty

This case study examines intersectionality pedagogy (IP) as a humanizing approach to teaching that centers Black women’s voices and experiences in higher education. Through Janice’s experience, the case illustrates how IP disrupts anti-Black, gendered racism and white-cis-hetero-...

Biodiversity tourism in production-conservation landscapes: stakeholder perspectives on high conservation value areas in oil palm plantations

Purpose Conservation spaces embedded within the production landscapes such as high conservation value (HCV) areas in oil palm plantations have traditionally been managed for biodiversity conservation, yet their potential as sites for biodiversity tourism remains underexplored. Th...

Exploring the Influence of Destination Sustainability, Credibility, and Trust on Rafting Behavioural Intentions: A River Tourism Perspective

This study aims to research the elements that impact tourists' inclination to undertake rafting tourism in Indonesia. Due to the scarcity of research on tourist behaviour in rafting tourism, this study conducted an online survey to collect data from a sample of 238 participants u...

Altering Moisture Transport Mechanisms in Multilayer Material Systems via Open Channel Networks for Enhanced Comfort

Abstract This study examines how the composition and structural configuration of two- and three-layer polymer-based systems influence thermophysiological comfort by altering water vapor transport mechanisms. Open moisture-transport channel networks were introduced into the top la...

Task-Adaptive Reinforcement Learning for Unified OCR in Maritime and Complex Documents

Maritime logistics relies on documents that combine dense multilingual text, irregular layouts, and task-specific output schemas, requiring operational systems to recover text, structure, location, and semantics. We trained Hi-Dolphin-OCRusing a task-adaptive reinforcement-learni...

Prior-conditioned edit prediction for real-time incremental updating of vectorized high-definition map

High-Definition (HD) maps are essential for intelligent transportation systems and autonomous driving, but their maintenance remains costly and time-consuming. Existing end-to-end perception models reconstruct vectorized HD maps from onboard sensors, whereas practical deployment...

Integrated LC–MS/MS Metabolomics and 16S rRNA Gene Sequencing to Identify Associated Molecular Signatures of Physalis Calyx seu Fructus Against Acute Pharyngitis

ABSTRACT This study aimed to characterize the metabolic and microbial alterations associated with Physalis Calyx seu Fructus (PCF) treatment in a rat model of acute pharyngitis (AP). The therapeutic effects of PCF on AP were evaluated by assessing physiological characteristics, a...

Effects of Acupuncture Combined With Core Stability Training on Pubic Symphysis Distance and Pelvic Floor Function in Patients With Postpartum Pubic Symphysis Diastasis

Objective This study aimed to evaluate the clinical efficacy of acupuncture combined with core stability training on pubic symphysis distance and pelvic floor function in patients with postpartum pubic symphysis diastasis (PSD). Methods A total of 179 postpartum patients with PSD...

Tail-Accuracy Degradation and Optimal Block Length for Block Self-Normalized Quantile Empirical Saddlepoint Inference under Dependence

Self-normalization combined with empirical saddlepoint approximation reaches higher-order tail accuracy under independent sampling, but under dependence the degradation is unquantified and the block length lacks a basis. This paper quantifies both for the block self-normalized qu...

Dry Mask Transfer Lithography for High-Resolution Patterning of Nanomaterials and Molecular Interfaces on Arbitrary Substrates

This study introduces dry mask transfer lithography as a versatile microfabrication strategy that integrates the patterning resolution of photolithography with the substrate adaptability of soft lithography. In this method, a photoresist mask is first patterned on an elastomeric...

New wine, old bottles? Effective strategies of new GenAI firms

Abstract Research Summary Blending insights from GenAI, strategic reasoning, and empirical grounding in five illustrative ventures, we contribute a theoretical framework for effective strategies of new GenAI firms. They face bifurcated uncertainty (i.e., high uncertainty of a nas...

Financial Structure and Profitability of Green Bond Issuers: Evidence Across Financial and Non-Financial Firms

Green bonds represent a significant financing instrument for climate mitigation and environmentally sustainable investments. Despite their growing importance, empirical evidence remains limited regarding the joint influence of firm-specific financial characteristics and macroecon...

Filler‐Regulated Pore Evolution Kinetics and Reliability Enhancement Mechanism of Sintered Ag Joints Revealed by Phase‐Field Simulation

ABSTRACT Wide‐bandgap semiconductor power devices generate substantial heat, demanding reliable thermal interface materials. Pressureless sintered Ag pastes offer high melting point and excellent thermal conductivity, but their inherent high porosity degrades reliability, and the...

Acute Ultra Low Dose THC Attenuates Anxiety-Like Behavior in a Mouse Model for Major-Depressive Disorder

Abstract Major depressive disorder (MDD) is a prevalent psychiatric disorder, and is a leading cause of disability worldwide. Current treatments for MDD entail many side effects, and include a lag until the onset of therapeutic effects. The current hypotheses as for the etiology...

Cheap Checks, Costly Decisions: What AI Really Costs in Anti-Money-Laundering Reviews

Banks use AI to prepare anti-money-laundering reviews of their customers. Even when the automated check becomes cheaper, analysts may have to spend more time verifying the evidence and recording who was authorised to take the decision. This article proposes a comparison protocol....