University of Wisconsin–Madison

Experiences of Perinatal Personnel With Values Clarification Workshops About Abortion

Importance Hospital-based labor and delivery (L&D) units have clinical expertise to provide second-trimester induction abortion and can help ensure patient access to abortion as legal and systematic barriers shift the US care landscape. However, hospitals may be reluc...

A Recurrent Tympanicum Paraganglioma With a SDHD Pathogenic Variant: First Reported Case

ABSTRACT Objective The aim of this study is to describe a clinical case of a SDHD germline mutation associated tympanic paraganglioma (TPGL). Patients A female patient seen in the otology clinic at a tertiary care center with a diagnosis of tympanic paraganglioma and significant...

Study protocol for first national vasa previa perinatal registry

Vasa previa is a rare but potentially catastrophic obstetric condition characterized by unprotected fetal blood vessels over or adjacent to the internal cervical os. Although advances in prenatal ultrasound have dramatically improved neonatal survival through planned cesarean del...

Redefining Successful Transition: Integrating Sexual and Reproductive Health into Transitional Urology

Abstract Purpose of Review Transitional urology has advanced over the past two decades, emphasizing readiness, self-management, and transfer to adult care. However, sexual and reproductive health is rarely included in measures of successful transition despite its importance to ad...

Estimating genetic correlation jointly using individual-level and summary-level GWAS data

Abstract With the increasing accessibility of individual-level data from genome wide association studies, it is now common for researchers to have individual-level data of some traits in one specific population. For some traits, we can only access public released summary-level da...

Revisiting the activate depress free and repeat (ADFR) paradigm: Clinical use of cyclic romosozumab

Abstract Summary Osteoporosis treatment does not normalize BMD. We hypothesized cyclic romosozumab dosing might provide greater BMD increases. Cyclic therapy (six romosozumab monthly doses then one denosumab dose) produced broadly similar BMD increases as previously reported for...

The fast destruction of methane by heterogeneous electrochemistry induced by martian dust activity: An experimental approach

Methane (CH 4 ) on Mars is of high scientific importance, particularly for its generation and destruction mechanisms. With an estimated photochemical lifetime of approximately 300 years, sporadic methane plumes observed on Mars by orbital, landed missions, and Earth-based telesco...

Pediatric Auditory-Perceptual Evaluation of Voice Part I: Voice Stimuli for Children

Purpose: The purpose of this study was to develop and test standardized stimuli for the Pediatric Auditory-Perceptual Evaluation of Voice protocol. The use of these stimuli for cepstral/spectral voice measures was also considered. Method: Three sets of standardized sentences and...

Spectral sequences, Massey products and homology of covering spaces

Abstract We revisit the equivariant spectral sequence considered by Papadima–Suciu, and show that all its differentials are computed by higher order Massey products. As a first application, we extend to arbitrary field coefficients results of Pajitnov relating the size of Jordan...

Searching the Literature by Meaning: Benchmarking Free and Commercial Word Embedding Models on Social Work Text

<p><b><i><span>Purpose</span></i></b><span>: Locating relevant studies is the first step of evidence-based practice, yet most searching relies on keyword matching. Artificial intelligence (AI) tools called embedding models search by...

Developing Social Capital for College Teaching: Exploring Connections Between Faculty Teaching-Focused Personal Networks and Evidence-Based Teaching

Evidence-based teaching is widely recognized as critical for student learning in science, technology, engineering, mathematics, and medicine (STEMM), yet whether and how faculty develop these instructional practices through their social ties remains less well understood. To illum...

Power weight inequalities for spherical maximal functions

Abstract This paper is about spherical maximal functions with general dilation sets acting on functions in weighted $$L^p(|x|^\alpha )$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:msup> <mml:mi>L</mml:mi> <mml:mi>p</mml:mi> </mml:msup> <mml:msup> <m...

Genome-wide CRISPR screening identifies cellular factors controlling nonviral genome editing efficiency

After administering genome editors, their efficiency is limited by a multi-step process involving cellular uptake, trafficking, and nuclear import of the vector and its payload. These processes vary widely across cell types and differ depending on the nature and structure of the...

Genomic catalogue of giant viruses reveals expanded diversity and functional potential

Nucleocytoplasmic large DNA and Mirusviricota viruses exhibit taxonomic richness which continually expands due to metagenomic sequencing. Here we curate a database of giant virus metagenome-assembled genomes (GVMAGs V2), comprising 8,508 species-level representatives from 18,727...

Primary Care Clinical Rotations Are Associated with Shifts in Senior Veterinary Students’ Perceptions of Scope, Complexity, and Career Alignment

The study objective was to evaluate changes in senior veterinary students' perceptions of companion animal primary care and career preferences following a primary care clinical rotation. A multi-institutional survey was administered to veterinary students at 10 US colleges of vet...

Variation in Thyroidectomy Use in Low-Risk Thyroid Cancer: Analysis of a Statewide Claims Registry

Introduction Studies have shown variation in thyroidectomy use across geographic settings but have not examined statewide, procedure-specific (total thyroidectomy [TT] versus thyroid lobectomy [TL]) rates for thyroid cancer at the surgeon or facility level. This study aimed to ch...

A study protocol for developing an implementation strategy bundle to enhance adoption of pediatric familial hypercholesterolemia screening

Familial hypercholesterolemia (FH) is the most common primary lipid disorder of childhood, affecting 1 in 250–350 children. Universal childhood cholesterol screening is an opportunity for earlier and more effective FH diagnosis and treatment that is superior to adult screening in...

African Economic Growth Revisited

ABSTRACT This paper presents an updated analysis of the patterns of economic development in Africa over the last 60 years. The analysis stresses the heterogeneity of development trajectories among sub‐Saharan African (SSA) countries. We examine the joint dynamics of income and po...

Spine Centers in Northeastern United States: Assessing Similarities and Disparities to Build more Homogeneity Across the Country

PROPOSE OF REVIEW: Spine centers are common, but no standardized regulations govern their designation. Existing certifications are issued by multiple independent organizations and are not necessarily equivalent, while many centers remain non-accredited. Consequently, centers may...

The evolution of plasticity in drought-related traits in central and edge populations of Mimulus cardinalis

Phenotypic plasticity can influence population persistence, range dynamics, and evolutionary potential in heterogeneous landscapes. If adaptive, plasticity may buffer populations against environmental variability, climate change, and extreme events. Yet, few studies have examined...