University of Washington

Pilot-Scale Demonstration of Foam Fractionation and Hydrothermal Alkaline Treatment for PFAS Removal and Destruction in a Municipal Wastewater Stream

Abstract Municipal wastewater treatment plants (WWTPs) are a known focal point for per- and polyfluoroalkyl substance (PFAS) accumulation, transformation, and transport. PFAS from disparate household and industrial sources are conveyed to central WWTPs and often end up in municip...

High sensitivity C-reactive protein and the risk of cardio-kidney outcomes in adults with moderate to severe chronic kidney disease: a nationwide study

BACKGROUND AND HYPOTHESIS: The burden and prognostic significance of inflammation in chronic kidney disease (CKD) remains poorly characterized, with prior studies yielding conflicting estimates of the association between elevated high-sensitivity C-reactive protein (hsCRP) and ca...

Wavelength-Dependent Photoluminescence Mapping of Depth-Dependent Degradation Under Thermal Stress in Phenethylammonium Tetrafluoroborate Treated Perovskite Solar Cells

Abstract Studying real-time degradation in perovskite semiconductors remains an important challenge. Conventional methods often cannot separate interfacial and bulk processes or rely on destructive analysis. Here, we demonstrate multiwavelength excitation photoluminescence (PL) a...

Cutaneous phaeohyphomycosis with the recently described fungus Gloniopsis leucaenae: first case report

Abstract Background Fungi of genus Gloniopsis are plant pathogens within class Dothideomycetes, rarely described to cause human infection. Species Gloniopsis leucaenae ( G. leucaenae ) was first isolated in 2019 and previously reported only in plant matter in Thailand. Case prese...

Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression

Abstract Prenatal maternal depression may have intergenerational effects on offspring brain development, with potential socioemotional consequences. This observational follow-up study examines brain development and subsequent negative emotionality among 109 infants born to mother...

Quaternion Dirac–Coulomb–Breit integral transformation for relativistic four-component correlated electronic structure theory

High-accuracy correlated four-component relativistic electronic structure methods are typically formulated in terms of integrals over molecular orbitals (MOs). Consequently, an efficient and scalable strategy is required to deal with the complexity of transforming relativistic tw...

Computation-through-Dynamics Toolkit: Simulated datasets and quality metrics for dynamical models of neural activity

A primary goal of systems neuroscience is to discover how ensembles of neurons transform inputs into goal-directed behavior, a process known as neural computation. A powerful framework for understanding neural computation uses neural dynamics – the rules that govern how neural ac...

First-In-Human Study of 211 At-CD45 Radioimmunotherapy With Nonmyeloablative Conditioning Hematopoietic Cell Transplantation for Adults With Hematologic Malignancies

Purpose Relapse is the dominant cause of failure after allogeneic hematopoietic cell transplantation (HCT) for aggressive hematologic malignancies. CD45-directed radioimmunotherapy (RIT) has been investigated to intensify conditioning and augment antitumor efficacy. After gaining...

Parents’ Attributed Gains in Participating in a Telephone-delivered Educational Counseling Program: A Qualitative Study

Purpose To describe gains child-rearing parents with advanced cancer attributed to their participation in a telephone-delivered educational counseling program on parenting. Methods Parents were eligible if they were diagnosed with advanced stage cancer, rearing a child 5-17 years...

Coupled transport equations with freezing

We study a system of two coupled transport equations with freezing. The solutions freeze in time when they are equal. We prove existence and uniqueness of continuous solutions if the initial conditions are continuous. We discuss several qualitative and quantitative properties of...

Implementation of a Bilingual Research and Evaluation Workshop for Community Health Workers, Promotores de Salud, and Community Leaders in Washington State

Community health workers, promotores de salud (CHW/Ps), and other community leaders play a crucial role in promoting health and addressing health inequities. Through their roles as trusted community members, they deliver culturally and linguistically appropriate health and social...

From plan to plate: Assessing food systems and equity considerations in historical and contemporary comprehensive plans from four U.S. cities

Urban planning is a structural driver of health, shaping environments that influence everyday activities and resources that can enable or inhibit health, including food systems. Yet, the extent to which comprehensive plans support equity and how this has evolved remains underexpl...

Aberrant one-carbon metabolism and ancestral genetics underlie edematous severe acute malnutrition

Edematous severe childhood malnutrition is distinct from the non-edematous form of malnutrition and remains a major cause of under-five mortality. Its etiology remains unclear, although aberrant one-carbon metabolism has emerged as a potential contributor. Here, we assess genetic...

Deep hydrous melting of the mantle wedge recorded by Mg isotopes

Subduction zones govern Earth’s deep volatile cycle. The slab-mantle interface is a key locus of volatile exchange between the subducting crust and the overlying mantle wedge, yet whether and how chemical reactions at this interface affect arc magmatism remains poorly constrained...

Predicting Self-Harm Events After Emergency Department Visits Associated With Mental or Substance Use Disorder Diagnoses

OBJECTIVE: Using a machine learning model, the authors aimed to predict self-harm events within 90 days of an emergency department (ED) visit associated with a mental or substance use disorder diagnosis. METHODS: Electronic health record and claims data of patients ages ≥11 years...

An inspiration-off attractor supports the robust and flexible control of breathing

Breathing is a fundamental motor rhythm necessary to sustain life. The rhythm and pattern of breathing arises from the coordination of a rostrocaudally extended ventral respiratory column (VRC) in the medulla. Although recurrent excitation is sufficient for rhythmic bursting in r...

System design of the Ultra Mobility Vehicle: A driving, balancing, and jumping bicycle robot

Trials cyclists and mountain bike riders can hop, jump, balance, and drive on one or both wheels. This versatility allows them to achieve speed and energy efficiency on smooth terrain and agility over rough terrain. Inspired by these athletes, we present the design and control of...

Broadband Near-Field Imaging of Strong Polariton Coupling in Graphene/CrI3 Heterostructures

Abstract Interfacial charge transfer in van der Waals heterostructures provides a powerful, contact-free mechanism to activate two-dimensional plasmons. Chromium iodide (CrI3), a layered ferromagnetic insulator, induces significant doping in adjacent graphene, yet its nanoscale p...

Dose-Escalated Focal Salvage High-Dose-Rate Brachytherapy and Genomic Classifier Risk Stratification in Radiorecurrent Prostate Cancer: The F-SHARP Phase I/II Clinical Trial

Purpose Prospective data on the management of intraprostatic radiorecurrence (IPR) after definitive radiotherapy (RT) and use of genomic classifiers (GC) in this setting are limited. We hypothesized that dose-escalated focal salvage high-dose-rate brachytherapy (DE-fsHDR) would b...

Association of Early Primary Care Follow-Up With Acute Care Use After ICU Discharge

OBJECTIVE: To determine if early primary care follow-up after pediatric intensive care unit (PICU) hospitalization is associated with reduced acute care use. METHODS: Using claims data from publicly and privately insured children, we identified a cohort of PICU hospitalizations f...