University of Michigan

SafeSpeaker: Voice Obfuscation for Resource-Constrained IoT Devices

Embodied voice assistants offer an intuitive and powerful interaction modality, but they also pose significant privacy-leakage risks when uploading raw voice recordings to the cloud for processing. These voice recordings contain a wealth of private information beyond just spoken...

Earinter: A Closed-Loop System for Eating Pace Regulation with Just-in-Time Intervention Using Commodity Earbuds

Rapid eating is common yet difficult to regulate in situ, partly because people seldom notice pace changes and sustained self-monitoring is effortful. We present Earinter, a commodity-earbud-based closed-loop system that integrates in-the-wild sensing, real-time reasoning, and th...

Rarefaction is better than robust Aitchison PCA and other compositional data analysis methods at controlling for uneven sequencing effort

Amplicon sequencing typically results in a wide distribution in the number of sequences obtained from each sample. How best to account for this variation has been a persistent problem in the microbial ecology literature. Historically, rarefaction has been used in ecology and this...

Neddylation E2 enzyme UBE2M inhibits inflammatory lung tumor microenvironment by blocking the cGAS-STING signal upon KrasG12D activation.

activation in the lung.

Real-world ctDNA test utilization and associated costs in US patients with bladder cancer who underwent radical cystectomy

BACKGROUND: Circulating tumor DNA (ctDNA) can inform prognosis and treatment effectiveness in bladder cancer. We evaluated real-world utilization and costs of ctDNA testing among US patients with bladder cancer undergoing radical cystectomy following initiation of Medicare covera...

Partitions of mass assignments with spheres and wedges

In this paper, we generalize classic mass partition results dealing with partitions using spheres, parallel hyperplanes, or axis-parallel wedges to the setting of mass assignments. In a mass assignment problem, we assign mass distributions continuously to all 𝑘 -dimensional subsp...

Design principle for solvent and abrasion resistant polydopamine coating: Intra- vs inter-particle crosslinking via UV-induced nitrene CH insertion

Bio-inspired polydopamine (PDA) coatings provide substrate-independent deposition via a simple aqueous dip-coating process but suffer from poor stability in strong alkaline and polar aprotic solvents and are vulnerable to abrasive damage because their assembly is dominated by cat...

Patient Risk Factors for Incidental Pathology After Uterovaginal Surgery for Apical Prolapse: Systematic Review and Global Expert Consensus Statements

Abstract Introduction and Hypothesis Uterus preservation is increasingly used for uterovaginal prolapse (U-POP) repair despite ongoing concerns regarding future uterine, cervical, and adnexal pathology. We evaluated incidental pathology rates, associated risk factors, and created...

Modeling and Simulation Techniques for Ultrahigh-Performance Concrete Materials and Structures

Abstract This paper presents a focused review of modeling and simulation strategies for ultrahigh-performance concrete (UHPC), emphasizing predictive capabilities, calibration demands, and multiscale consistency. Continuum damage plasticity and cap-based formulations are shown to...

Evolutionary regimes determine the accuracy of epistasis inference from temporal genetic data

Epistasis, the non-additive effects of mutations, shapes fitness landscapes and evolutionary trajectories. Temporal genetic data reveal evolutionary dynamics and could be used to infer epistatic interactions, especially through linkage disequilibrium (LD) between interacting muta...

“Clean” Meat? Regulatory Entrepreneurship and Jurisdictional Contestation in a Nascent Industry

In nascent industries, uncertainty about which regulatory agency has jurisdiction is often a major challenge for pioneering ventures. Yet, much of the literature on new ventures’ nonmarket strategy takes for granted the existence of a designated regulator. How do ventures manage...

Efficacy of Technology-Augmented Behavioral Counseling for Risky Firearm Behaviors

Importance Firearm violence is a leading cause of morbidity and mortality for US adolescents and emerging adults (A/EAs). Health care visits are an important opportunity to provide preventive counseling addressing risky firearm behaviors (RFBs), which increase fatal and nonfatal...

Diabetes and Suicide Risk Among Black Males, Including Sexual Minority Males: A Narrative Review With Primary Care Implications

Abstract Purpose of Review Diabetes and suicide are intersecting public health concerns, yet evidence at this intersection remains sparse for Black males and especially Black sexual minority males (SMM). This focused narrative review synthesizes direct and adjacent evidence, with...

Using inertial measurement units to characterize musculoskeletal risk factors in a pilot study of a passive shoulder exoskeleton during a drilling-fastening task

Exoskeletons have been considered for mitigating ergonomic risks of work-related musculoskeletal disorders (WMSDs), but they are not consistently utilized in initial deployments as workers in some facilities have not voluntarily used them. In this study, we investigated the impac...

Orthodontic, regenerative, and implant management of a mandibular anterior defect: 5‐year outcome

Abstract Background Severe alveolar ridge defects in the mandibular anterior region, often associated with congenital tooth absence and subsequent loss of retained primary teeth, present significant challenges for implant rehabilitation. Limited space, horizontal ridge deficiency...

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

ABSTRACT Hydrogels serve as powerful models for investigating cell‐extracellular matrix (ECM) interactions. While chemical modifications are routinely used to tune hydrogel properties, it remains unclear whether these modifications mediate cell fate. Previous work has shown that...

Infant-Toddler Court Teams and Reentry to Foster Care

Infant–Toddler Court Teams (ITCTs) are associated with higher rates of reunification and kinship permanency, but less is known about whether these gains are sustained after children exit care. This study examined reentry to foster care within 12 months of an eligible permanency e...

In situ EBSD characterization of static recrystallization in a Mg-Zn-Ca (ZX30) alloy

The recrystallization behavior of a hot-compressed Mg–3Zn–0.1Ca (ZX30) alloy during static recrystallization was investigated in situ using electron backscatter diffraction (EBSD). The material was subjected to 5% plane-strain compression at 200 °C, and subsequently exposed to su...

Predicting [177Lu]Lu-PSMA-617 SPECT/CT-based absorbed dose to whole-body tumor volume from pre-therapy [68Ga]Ga-PSMA-11 PET metrics and common blood biomarkers

It has been shown that absorbed dose (AD) to whole-body tumor volume (WBTV) from [ 177 Lu]Lu-PSMA-617 radiopharmaceutical therapy (RPT) correlates with treatment response. Pre-therapy estimation of AD to WBTV could therefore aid clinicians with patient selection and dosimetry-gui...

Measuring solid-liquid interfacial properties outside of equilibrium via synthetic driving force molecular dynamics simulations

The solid-liquid interfacial free energy γ and mobility M are critical parameters governing solidification microstructures, but their precise determination outside of equilibrium remains a significant challenge. In this study, we propose a novel computational methodology to deter...