University of Miami

Non-canonical pore architecture underlies constitutive gating of human retinal TRPM1

Transient receptor potential melastatin 1 (TRPM1), a Ca²⁺-permeable nonselective cation channel essential for retinal ON bipolar cell signaling and night vision, and implicated in congenital night blindness, has remained structurally and functionally poorly characterized. Here we...

Mitochondrial subpopulations in oocytes and cumulus cells exhibit distinct age-associated changes and selective plasticity in response to NMN supplementation

Abstract Background Mitochondrial dysfunction is a leading contributor to the decline in oocyte quality associated with maternal aging. Prior investigations of mitochondrial function in the ovarian follicle have largely treated the mitochondrial pool as a homogeneous population,...

Cold Atmospheric Plasma Disrupts Microbial Wound Bioburden: In Vitro, Porcine MRSA Biofilm, and Clinical Fluorescence Evidence from Bench to Bedside

Background: Biofilm-associated microbial burden is a major barrier to wound healing and is increasingly difficult to control in the era of antimicrobial resistance. This translational study evaluated the antimicrobial performance and tissue compatibility of a commercially availab...

Performance of mechanochemically activated supplementary cementitious materials in cement pastes and mortars

Abstract Mechanochemical activation (MCA) is a rapidly emerging technology for producing supplementary cementitious materials (SCMs). However, performance data on MCA SCMs is lacking. Here, we investigated the potential use of four low-grade materials as sources of alternative SC...

Exploring Middle and High School Personnel’s Definition and Knowledge of Evidence-Based Practices for Autistic Students

Background Mandates that educators use evidence-based practices (EBP) with autistic students have not led to their widespread or consistent implementation, despite their growing availability. EBP knowledge is integral to effective implementation, and prior studies have shown that...

Message design for guilt-based green advertising: whether and how to highlight moral transgression, personal responsibility, and efficacy

Guilt appeals are frequently used in green advertising. However, there has yet to be an agreement reached on the development of guilt appeals. Based on appraisal theories and extended parallel process model, our study proposes that three appraisal-related message components (i.e....

A Commentary on “Radical Nephrectomy and Thrombectomy Without Cardiopulmonary Bypass for Level IV Venous Thrombus Renal Cell Carcinoma: Feasibility and Technical Tips”

demanding cases