University of Miami

Timing and safety of prone positioning following median sternotomy in infants with single-ventricle physiology

Abstract Background: Prone positioning is an essential component of early rehabilitation and motor development in infants following cardiac surgery involving median sternotomy; however, restrictions remain variable due to concerns regarding sternal healing and safety. Due to a la...

Prioritizing Global Health Education in Pulmonary and Critical Care Fellowships: An Applicant Survey

Abstract Background Global Health (GH) is expanding, offering an increasing number of opportunities for engagement to trainees in medical schools and residency programs. This expansion of opportunities has not yet reached those at the fellowship level, particularly in Critical Ca...

Two-way Homogeneity Pursuit for Quantile Network Vector Autoregression

We propose a two-way grouped network quantile (TGNQ) autoregression model for time series data observed on networks with substantial heterogeneity and complex directional interactions. Motivated by prior studies on network effects in directed networks, our model assigns each node...

AANEM Consensus‐Based Guideline for Grading the Severity of Carpal Tunnel Syndrome

ABSTRACT Electrodiagnostic (EDX) reports for patients with carpal tunnel syndrome (CTS) often include a description of severity, but considerable variability in approach creates confusion for referring physicians, patients, and EDX practitioners. The purpose of this project was t...

Outcomes of CHOP versus CHOEP/EPOCH in aggressive adult T-cell leukemia/lymphoma: an international cohort analysis

Aggressive adult T-cell leukemia/lymphoma (ATL) subtypes (i.e., acute and lymphomatous) are rare diseases, and the conventional management with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) has historically yielded poor outcomes. The benefit of etoposide-conta...

Why Metrics Matter in Thyroid Eye Disease

Importance Advances in the understanding of the pathophysiology of thyroid eye disease (TED) provide an opportunity to use novel, targeted therapeutic agents. However, our capacity to assess the efficacy and indications for the new agents is potentially limited by the clinical me...

Do negative alliance signals increase public support for nuclear weapons?

For decades, the United States has sought to prevent its allies from acquiring nuclear weapons. To this end, the United States has attempted to reassure those allies that it is committed to defending them. Recent experimental work, however, suggests that increased alliance credib...

On the Geographic Spread of Chikungunya Between Brazil and Florida: A Multipatch Model with Time Delay

Abstract. Chikungunya (CHIK) is a viral disease transmitted to humans through the bites of Aedes mosquitoes infected with the chikungunya virus (CHIKV). CHIKV has been imported annually to Florida in the last decade due to Miami’s crucial location as a hub for international trave...

3D-Printed Poly(Lactic-co-Glycolic Acid) Binder-Based Self-Hardening Calcium Phosphate Bone Scaffolds

Three-dimensionally (3D)-printed alpha-tricalcium phosphate (α-TCP) scaffolds, fabricated through a low-temperature hydrothermal dissolution-precipitation process, replicate the structural and compositional features of native bone. Reinforcing hydrothermally processed α-TCP with...

Unravelling the Itch: Cross‐Sectional Analysis of Pruritus Patterns in the PicnicHealth Primary Biliary Cholangitis Registry

BACKGROUND & AIMS: Pruritus in primary biliary cholangitis (PBC) worsens patients' health-related quality of life (HRQoL). Serum alkaline phosphatase (ALP), a biomarker of PBC activity, has an unclear relationship with pruritus severity. METHODS: This retrospective, cross-section...

TM184C is a GPCR-like regulator of intercellular exchange and autophagy

Sequence similarity underlies most protein annotation, yet many functions remain hidden beyond detectable homology1–3. By mining millions of AlphaFold2 models4,5, we identify two human families of ‘superdark’ seven-transmembrane proteins—TM184 and PRRT—with structural homology to...

Isolated Avulsion of the Distal Head of the Adductor Magnus: A Case Report

ABSTRACT: In the present case, we describe the first reported instance of a noncontact distal adductor magnus avulsion injury in a collegiate Division I football player. A 22-year-old male player initially presented with an acute posterolateral corner injury with partial thicknes...

Photochemical fluorescence activation in arrays of microspherical containers

Abstract Synthetic dyes with photoactivatable emission permit the photochemical control of the spatial distribution of fluorescence. When their diffusion is restricted in a host matrix, patterned illumination enables the photochemical imprinting of information in the form of pers...

A Mixed Methods Examination of Youth in Foster Care's Trust in Social Institutions

Youth in foster care interact at the intersection of multiple systems. Experiences and relationships within each system may facilitate or hinder youths’ trust. Importantly, trust has been identified as a potential contributor to improved school and life outcomes for youth in fost...

Research on the ecology of the carnivorous sponge-associated iridovirus (CaSpA-IV) reveals its presence in the Cnidaria

Carnivorous sponge–associated iridovirus (CaSpA-IV) is a recently described virus identified in two deep-sea cladorhizid sponge species from the Gulf of Maine and Baffin Bay. To assess its ecological distribution and potential transmission pathways, we molecularly screened for Ca...

Clinical Characteristics and Outcomes of Melanoma Among Latin American Adolescents and Young Adults Compared to Middle-Aged and Elderly Population: A Cohort Analysis Over 10 Years

Introduction: Outcomes among the Hispanic population are rarely explored in adolescents and young adults (AYAs). We aimed to compare sociodemographic, clinical, and survival outcomes of Latin American AYAs (≤39 years) with middle-aged (40–59 years) and older (≥60 years) patients...

Assessment of small watershed stormwater sampling methods

ABSTRACT Measurements of contaminants in runoff are essential for stormwater management. Sampling accuracy is difficult to assess due to the cost and labor of field studies and the large variation in runoff behavior between sites, rain events, and pollutants. Stormwater sampling...

Unmet Pet Caregiving Needs are Associated with Depression and Anxiety Symptoms Among People Living with HIV

People living with HIV (PLWH) experience disproportionately high rates of depression and anxiety. Human–animal interactions (HAI), particularly through pet ownership, may provide emotional support and companionship; however, the human–animal bond can be threatened by structural a...

Resolving Convective‐Scale Cloud and Precipitation Structures in Tropical Cyclone Rainbands With Novel Raman Lidar Observations

Abstract Low‐level clouds in the tropical cyclone (TC) rainbands modulate the radial inflow of warm, moist boundary layer air, which can impact TC intensity. Yet, precisely measuring rainband cloud boundaries with existing remote sensing techniques remains a challenge. To address...

Safety and Effects of Gildeuretinol Acetate on Retinal Atrophic Lesions in Stargardt Disease

Importance Stargardt disease (STGD) is the most common macular dystrophy, resulting in profound loss of vision. There is no approved treatment. Objective To evaluate the safety and effects of oral gildeuretinol acetate on the growth of retinal atrophic lesions in individuals with...