University of Bonn

From public genome data to biological insight: A computational workflow for in silico restriction site analyses

This poster was presented on the TRA Workshop "Great Data, Great Science" at the University of Bonn on 06 October 2026. --- In computational biology, the availability and careful handling of high-quality digital data are essential for obtaining reliable and biologically meaningfu...

A KK-theoretic note on the spectral localiser

Abstract We review the construction of the spectral localiser (due to Loring and Schulz-Baldes) from a KK -theoretic perspective. We first give a KK -theoretic argument providing a spectral flow expression for the even or odd index pairing in terms of the “infinite volume” spectr...

Regulatory Networks Underlying Plant Nutrient Status

Plants require 14 mineral nutrients for growth and development. Nutrient imbalances remain major constraints on agricultural productivity. Conventional approaches for diagnosing plant nutritional status often fail to identify the primary limiting element, particularly in acidic s...

Study of B+ → μ+νμ decays at Belle and Belle II

This thesis presents a study of the leptonic B+ → μ+νμ decay using data collected at the Belle and Belle II experiments. The branching fraction of the B+ → μ+νμ decay is determined by examining the muon momentum in the rest frame of the B meson. A data set corresponding to an int...

Holistic Modeling Approaches for Supporting Sustainability Transitions

Agricultural and environmental decisions in agroecological systems are made under profound uncertainty, with complex trade-offs between productivity, ecological integrity and human well-being. This cumulative habilitation thesis brings together 32 peer-reviewed studies that devel...

Development of a prediction model for occupational satisfaction among cancer patients following counseling in German psychosocial cancer counseling centers

Abstract A prognostic model was developed and internally validated to predict satisfaction with the occupational situation among cancer patients receiving psychosocial counseling regarding return to work (RTW). Data were collected from outpatient cancer counseling centers in Germ...

Long-term climatology of vertical profiles of polarimetric variables and ice-microphysical retrievals at X-band – Part 1: Radar calibration

In a two-part series of papers, a climatology of quasi-vertical profiles (QVPs) of polarimetric variables and ice-microphysical retrievals such as ice water content, total number concentration and mean volume diameter is presented. QVPs are generated from plan position indicator...

Toward the Use of Real‐World Data for Regulatory and HTA Decision‐Making: Experiences and Recommendations from Six EU ‐Funded Projects

Real-world data are increasingly important for regulatory and health technology assessment decision-making, yet their effective use across Europe remains limited by technical, methodological, regulatory, and societal challenges. Drawing on the experiences of six Horizon Europe pr...

The global cost of schizophrenia: a health economic modelling study

Abstract Background Schizophrenia is a chronic psychiatric disorder that leads to substantial disability, impaired quality of life, and reduced life expectancy. In addition to its profound impact on affected individuals, the disorder places a considerable financial burden on heal...

Testing machine-learned distributions against Monte Carlo data for the QCD chiral phase transition

A bstract We demonstrate that conditional Masked Autoregressive Flows constitute a flexible interpolation tool for lattice QCD observables, conditioned on bare lattice parameters. As a benchmark, we use the chiral phase structure of QCD with five degenerate light quark flavours,...

THz-driven scanning tunneling-induced luminescence: a brief review

Terahertz-lightwave-driven scanning tunneling microscopy (THz-STM) enables femtosecond control of tunneling currents by transiently gating the junction bias with single-cycle THz pulses. STM-induced luminescence (STML), on the other hand, provides spectrally resolved optical acce...

Understanding the near-threshold structures in $$e^+e^-$$ annihilation from a unified $$N\bar{N}$$-interaction perspective

Abstract Near-threshold structures have been observed in the cross sections for $$e^+e^-\rightarrow p\bar{p}$$ e + e - → p p ¯ , $$e^+e^-\rightarrow n\bar{n}$$ e + e - → n n ¯ , and several non-baryonic final states in the vicinity of the $$N\bar{N}$$ N N ¯ thresholds. We investi...

Amphiphilic Motif Triggers Microheterogeneity in Low‐Melting Mixtures

Microheterogeneity in low‐melting mixtures of ethylene glycol and chemically modified choline derivatives synthesized on purpose is here proposed. Novel cholinium ions with one or two N ‐butyl substituents or an N ‐hydroxybutyl chain are synthesized for the first time. Synthesis...

The orofacial cleft risk gene IRF6 is a target gene of SOX9 in cranial neural crest cells

Abstract Orofacial clefts represent the most prevalent congenital anomalies affecting the craniofacial region. They can be evoked by a disturbed development of either oral epithelium or cranial neural crest-derived mesenchyme, or by disruptions of their interplay. IRF6 is a well-...

Multi-facility GNSS antenna calibration

Abstract Accurate antenna calibrations are a cornerstone of high-quality global navigation satellite systems (GNSS) positioning, time and frequency transfer, precise orbits, and troposphere estimates. The international GNSS service (IGS) antenna committee maintains antenna phase...

Decoding the autotetraploid origin of the stress-tolerant wild beet Beta corolliflora

Abstract Background Most crop plants, including sugar beet ( Beta vulgaris subsp. vulgaris ), suffer from domestication bottlenecks and low genetic diversity caused by extensive selection for few traits. However, crop wild relatives (CWRs) harbour useful traits relevant for crop...

Mitochondrial fitness for sustainable male health – a 3PM-guided healthcare innovation

Abstract Male health is much more than only an essential pillar of the sustainable socio-demographic development of each society. To this end, erectile dysfunction, preventable male infertility, and urological cancers (including testicular, bladder, kidney, prostate, and penile o...

Towards higher Frobenius functors for symmetric tensor categories

Abstract We develop theory and examples of monoidal functors on tensor categories in positive characteristic that generalise the Frobenius functor from [5, 17, 22]. The latter has proved to be a powerful tool in the ongoing classification of tensor categories of moderate growth,...

Melt evolution and crystal cargo uptake at Mount Ruapehu: a magma plumbing system characterized by narrow dikes and sills

Abstract To assess the magma plumbing architecture of Mount Ruapehu, an active stratovolcano in the Taupō Volcanic Zone (New Zealand), we combine whole rock, groundmass and crystal geochemistry of lava samples from the south-west flank, focusing on the Mangawhero (50–15 ka) and W...

Deforestation‐Free Cocoa: Implications for Organizational Adaptation and Compliance Costs

ABSTRACT Mandatory due diligence is an emerging policy instrument for addressing global environmental challenges, yet how such regulations reshape firm‐level organizational structures and generate compliance costs remains poorly understood. Drawing on organizational theory, this...