Université Paris Cité

Terminology for describing the 24-h cycle of physical activity, sedentary behaviour, and sleep: a scoping review

Abstract Background Physical activity, sedentary behaviour, and sleep are three behaviours which occupy the 24-h cycle and interact to influence a multitude of health outcomes. Different terms are currently used to describe these behaviours collectively (e.g., movement behaviours...

Chemical desorption of methanol induced by hydrogen abstraction–addition cycles on cold grain surfaces

Abstract We report ultra-high vacuum experiments on the non-thermal desorption of methanol (CH3OH) from cold dust-grain analogues under hydrogen-atom bombardment. Monolayer methanol films on polycrystalline gold, compact amorphous solid water (ASW, 10 ML) and 13CO ice (2 ML) are...

Fertility-Sparing Management of Atypical Hyperplasia and Endometrial Cancer from the Perspective of Molecular and Hormonal Profiles: A Meta-Analysis-Driven Framework

Background/Objectives: The prognostic and predictive values of biomarkers in fertility-sparing management of atypical hyperplasia (AH) and endometrial cancer (EC) remain ill-defined. We aimed to identify the impact of tumour profiles on oncologic and reproductive outcomes to info...

Microglial maturation across human and mouse as a reference for interpreting large-animal models of perinatal brain injury

Abstract Microglia play dynamic roles in the developing brain and are central mediators of injury responses in perinatal brain injury. In mice, microglial gene regulatory and transcriptional programes reveal progression through early, pre-mature and mature stages. In contrast, mi...

Very‐Long‐Period Seismic Signals During Lateral Dike Propagation at Piton de La Fournaise Volcano

Abstract We report a previously undocumented sequence of very long period (VLP) signals preceding the September 2022 eruption at Piton de la Fournaise. These events occurred during lateral magma propagation and exhibit quasi‐periodic sawtooth‐shaped displacement transients. Seism...

Analysis of bone metastasis multidisciplinary team meeting activity in a university hospital: patient profiles, prognostic factors

Bone metastases a represent a challenge in the oncological management of patients as the complications can be severe, as fractures or neurological impairment in spinal metastases. Recommendations on the management of bone metastases are constantly being improved. However, there a...

Alcohol and tobacco in cancer: A unified framework of interaction across carcinogenic pathways and cancer types

Background Alcohol and tobacco are among the leading preventable causes of cancer worldwide and frequently co-occur. While both are well-established independent carcinogens, their combined effects remain insufficiently characterized and inconsistently interpreted across cancer ty...

Genetic screening identifies WNT5A/RYK as a determinant of extracellular vesicle fate

Extracellular vesicles (EVs) are natural mediators of intercellular communication through the transfer of cytoplasmic material from donor to recipient cells. The molecular mechanisms governing EV uptake and cargo delivery in recipient cells remain largely elusive. To address this...