The University of Sydney

Women’s Attitudes toward the 2024 US Preventive Services Task Force Mammography Screening Guideline

Background: From 2009 to 2024, the US Preventive Services Task Force (USPSTF) recommended that women aged 40 to 49 y make an informed choice about when to begin having mammograms. In 2024, the USPSTF changed its guidelines, recommending biennial screening from age 40 to 74 y. Thi...

Investigating the role of excipients in mitigating surface adsorption, aggregation and structural degradation in liquid phage formulations

The race to produce therapeutically acceptable phages is driven by their rapid loss of infectivity, placing strain on laboratories, healthcare infrastructure and patients. Enhancing product shelf-life will alleviate this barrier to their upscaling and clinical application. We sys...

Topic: piloting adapted WHO digital interventions for health system strengthening in primary care mental health in Nigeria: a mixed-methods RE-AIM evaluation

Mental health treatment gaps persist across low- and middle-income countries despite task-shifting initiatives integrating mental healthcare into primary care. Digital health interventions were piloted within the Mental Health in Primary Care (MeHPriC) programme in Lagos, Nigeria...

Multifactorial and multiple component interventions for preventing falls in older people living in the community

RATIONALE: Multifactorial fall prevention interventions are those where intervention components are tailored to each person's individual fall risk factor profile. Multiple component interventions provide the same components to everyone. The evidence on the effects of these interv...

Eye Findings Following Congenital Cytomegalovirus Newborn Screening

BACKGROUND AND OBJECTIVE: Consensus guidelines have recommended eye examinations for all newborns with congenital cytomegalovirus (cCMV) infection; however, structured ophthalmic examinations are seldom reported. Existing literature suggests ocular pathology is uncommon in cCMV,...

W8. HERITABILITY OF ACCELEROMETRY-DERIVED FEATURES OF PHYSICAL ACTIVITY, SLEEP AND CIRCADIAN RHYTHMICITY AND THEIR JOINT INFLUENCES IN YOUNG PEOPLE

Background Dysregulation of motor activity and sleep are key components of several mental disorders, particularly mood disorders and attention deficit hyperactivity disorder (ADHD). There is growing evidence that profiles of 24-hour activity patterns may discriminate subgroups of...

Liquid–Metal-Induced Metal–Support Interactions for CO2 Hydrogenation

Abstract Metal–support interaction (MSI) is central to numerous industrial heterogeneous catalytic processes yet its classical realization typically requires high-temperature treatment (typically >500 °C), which often induces metal sintering and excessive encapsulation. Herein, w...

Lenalidomide maintenance after initial immunochemotherapy in chronic lymphocytic leukaemia—Final analysis of the international phase III CLL6 RESIDUUM study of the ALLG and FILO groups

Summary Most patients treated for chronic lymphocytic leukaemia (CLL) fail to achieve measurable residual disease (MRD) negativity. The role of maintenance with the immunomodulatory drug lenalidomide in these patients is unclear. A randomised multicentre phase III trial (ACTRN126...

Storiform Collagenomas With Unusual Morphology: Expanding the Histologic Spectrum in Two Molecularly Proven Cases

ABSTRACT Storiform collagenoma is a rare benign dermal neoplasm recently shown to harbor concurrent PTEN and PDGFRB mutations. While most are sporadic, a subset occurs in the context of Cowden syndrome. We describe two storiform collagenomas with unusual morphology including infi...

Psychosocial, behavioural, health, and productivity-related factors associated with public transport use and walking for transport among infrequent bus users in a regional area

Background and aims Public transport (PT) users are typically more physically active compared with private vehicle users. This study aimed to determine the variables associated with objectively measured PT use and self-reported walking for transport among infrequent bus users in...

Giddy up! Can We Reduce Dropouts in a Discrete-Choice Experiment by Including an Encouraging Message? A Randomised Trial

Background: Discrete-choice experiments (DCEs) are valuable in establishing health preferences. However, their repetitive nature may cause dropouts. Aim: Does an encouraging ‘giddy-up’ message improve completion rates, data quality and respondent experience? Design: Two online DC...

Triangulations of the 3-sphere with knotted edge

We prove that for any knot K , there exists a decomposition of the 3-sphere into tetrahedra such that a representative of K is formed from one vertex and one edge of the decomposition. The proof is constructive, and based on fully augmented links. We use our method to produce a f...

THE PROOF IS IN THE CHECKING

Abstract This paper investigates the question: what is a formal logical proof (in general—as opposed to: what is a formal proof in this or that specific proof system)? I begin by setting out a core conception of formal proof and substantiating its designation as ‘core’. The heart...

Annealing‐Induced Crystalline Reconstruction and Toughening Mechanisms in β‐Nucleated Long Glass Fiber‐Reinforced Polypropylene Random Copolymer

ABSTRACT Long glass fiber‐reinforced modified polypropylene random copolymer (LPM) systems are widely applied in lightweight structural components. However, rapid injection molding induces heterogeneous crystallization, limiting mechanical performance. Moreover, the intrinsic bri...

Growing old before growing up

Frailty is a condition commonly associated with aging, characterized by functional and cognitive decline, increasing dependence, and early mortality, but it is rarely conceptualized in children. We present a caregivers' perspective on frailty in her daughter living with childhood...

Impacts of a Statewide Prescription Drug Monitoring Program—Healthcare Practitioner Perspectives

ABSTRACT This study examined the perceived impacts of New South Wales' (NSW) statewide prescription drug monitoring program (PDMP; “SafeScript NSW”) from the perspective of prescribers and pharmacists, using a qualitative descriptive design. Fourteen prescribers and pharmacists w...

Probing context-sensitive expectations through user-driven personality configuration in conversational AI

Abstract Conversational agents are increasingly expected to adapt across contexts and evolve their personalities through interactions, yet most remain static once configured. We present an exploratory study of how user expectations form and evolve when agent personality is made d...

Health‐Related Quality of Life in Adults With Congenital Heart Disease: A Population‐Based Study

Background As survival into adulthood improves for patients with congenital heart disease (CHD), quality of that survival is paramount. We assessed health‐related quality of life (HRQL) in a large adult CHD cohort. Methods We studied 868 participants from a multicenter registry w...

ACPSEM guideline regarding the adoption of the IAEA TRS-398 Code of Practice Revision 1

Abstract The IAEA Technical Report Series 398 Code of Practice for the determination of absorbed dose in external beam radiotherapy was endorsed at the Engineers and Physical Scientists in Medicine (EPSM) conference in 2001 and has been widely adopted in Australia and New Zealand...

Indices of obesity, malnutrition and inflammation are strong predictors of mortality in adults with type 2 diabetes: the FIELD study

Abstract Aims/hypothesis Metabolic risk in type 2 diabetes is not fully captured by standard clinical measures. Use of NMR-based metabolomic indices may enhance risk prediction, but their role in individuals with type 2 diabetes is unresolved. Methods We analysed data from 9550 a...