The University of Sydney

Areths and the Provisional Polythetic Areth Classification System (PPACS): a hierarchical and nomenclatural framework for Martian soil classification

The absence of a formally defined and operationally robust classification system for Martian soil material represents a critical gap in planetary science. While substantial compositional and remote sensing data exists, these datasets have not yet been integrated into a coherent,...

Targeted Philanthropy: Evidence from M&As

ABSTRACT I show how firms optimize the allocation of charitable funds around investments that require external stakeholder support, such as mergers and acquisitions. Acquirers increase donations to target‐related charities before making a takeover offer, but scale funds back afte...

Experiences of sexual rehabilitation post-stroke among LGBTQI+ stroke survivors and their partners: a qualitative study

Introduction Little is known about sexual rehabilitation for LGBTQI+ stroke survivors and their partners. This study explored the experiences of LGBTQI+ stroke survivors and their partners in relation to post-stroke sexual rehabilitation.Methods A qualitative phenomenological res...

Vascular device practices in extremely preterm infants: an international cross-sectional survey

Abstract Objective To explore global practices in vascular device selection, securement, and monitoring for extremely preterm infants, and to assess regional variation. Study design A web-based cross-sectional survey was completed by one respondent per neonatal unit. Result We re...

DHODH is the key target of the KDM4 inhibitor QC6352 in glioblastoma stem cells

Abstract Histone lysine demethylase 4 (KDM4) enzymes are frequently overexpressed in cancer and are considered to be promising therapeutic targets. QC6352, which is widely used as a best-in-class KDM4 chemical probe, shows potent antitumor activity across cancer models. Using com...

Who is inclined to embrace green options in on-demand mobility?

Shared on-demand mobility can be made more environmentally friendly, but this involves trade-offs in comfort and cost: electric vehicles may require higher fares due to charging time, while walking segments can reduce vehicle-kilometres-travelled at the expense of door-to-door co...

Reframing Museum Intelligence: A Survey of Large Language Models in Museums

Large language models (LLMs) have recently emerged as a transformative technology for museums, enabling a shift from static content delivery toward interactive and intelligent systems. However, existing studies and deployments remain fragmented, with a lack of systematic analysis...

From emergence to exposure: one health attribution of azole-resistant Aspergillus fumigatus in Southeast Asia

Southeast Asia is a hotspot for azole-resistant Aspergillus fumigatus yet remains underrepresented in global surveillance. Disciplinary approaches, including genomics, environmental sampling, and social science, have progressed but remain poorly integrated. We outline a One Healt...

Key considerations for window of opportunity trials and preoperative endocrine therapy in breast cancer

Window of opportunity (WOO) trials are short, pre-surgical trials which aim to evaluate novel therapeutic strategies and answer biological and mechanistic questions. Despite their relative simplicity, their conduct can be challenging. This Perspectives Article considers key facto...

Sliding-ferroelectric order imprinted onto excitonic and valley responses in van der Waals heterostructures

Ferroelectricity driven by interlayer sliding provides a distinct route to nonvolatile control in van der Waals (vdW) heterostructures, yet resolving stacking-dependent ferroelectric states and their local interfacial consequences remains challenging. Here, we report that bilayer...

Rehabilitation management of children with hereditary spastic paraplegia: a retrospective cohort study

Background Hereditary spastic paraplegia (HSP) is a group of rare, genetically heterogeneous neurodegenerative conditions characterized by progressive lower limb spasticity. In children, rehabilitation management of HSP is commonly extrapolated from cerebral palsy practice, despi...

Validation of the PANAMA Score in Patients With Pancreatic Ductal Adenocarcinoma Undergoing Distal Pancreatectomy

ABSTRACT Background The PANAMA score was developed as a post‐NAT prognostic tool for PDAC. Prior validations have been dominated by pancreatic head cancers. Pancreatic body and tail tumours represent a biologically distinct subgroup and remain underrepresented in NAT cohorts. Whe...

The Evolutionary Frameworks Project - 7 Additional Framework Models

The Evolutionary Frameworks Project – 7 Additional Framework Models documents the second major expansion of the Evolutionary Frameworks Project, an interdisciplinary scientific research programme developed by Kaya Genc, Silas Njiru John, and Dr James Barkell. Following publicatio...

Paediatricians' Support for Adolescent Vaping Cessation in Australia: A National Cross‐Sectional Study

ABSTRACT Background Adolescent vaping is rising globally and in Australia, and evidence on paediatricians' cessation support is scarce. This study examined predictors of paediatricians' engagement in vaping cessation among adolescents, focusing on disparities in knowledge, attitu...

Platformized family governance and the re-domestication of young people’s smartphone use in China

Chinese families increasingly govern smartphone use that supports schoolwork, peer communication, entertainment, and engagement with algorithmically recommended content. This platform convergence makes it harder to determine what counts as legitimate use, who should manage it, an...

Engineering neurovascular thrombosis: Light-based bioprinting for patient-specific modeling and women’s cerebrovascular health

Cerebral venous sinus thrombosis (CVST) and carotid web (CW) are distinct cerebrovascular disorders where vascular geometry, disturbed hemodynamics, and endothelial activation interact to drive thrombosis. Both conditions disproportionately affect women, yet remain understudied b...

Enhancing the Role of Digital Health Navigators With Lived Experience: AI-Assisted Conavigation for Safety, Support, and Engagement

As artificial intelligence (AI) expands across mental health services, questions arise about whether it can replace digital health navigators (DHNs), including those with lived experience. The DHN role generally resists automation because lived experience deepens specific dimensi...

QCD and electroweak phase transitions with hidden scale invariance: implications for primordial black holes, quark-lepton nuggets and gravitational waves

A bstract We study the cosmological implications of the minimal non-linear realisation of scale invariance within the Standard Model (SM). This framework provides a technically natural explanation for the hierarchy between the Planck scale and the electroweak scale and introduces...

Rethinking wireless communications through formal mathematical AI reasoning

Mathematical analysis has long underpinned wireless communication theory, yet the growing complexity of next-generation systems demands increasingly sophisticated reasoning from domain experts. Recent advances in AI mathematical reasoning, from formal theorem proving to large lan...

A multicenter multistate modeling on the natural history of liver decompensation: Longitudinal analysis of 1777 patients.

BACKGROUND: Cirrhosis often remains silent until decompensation, after which survival deteriorates sharply. Contemporary, transition-aware estimates are limited, especially in Asian-predominant cohorts. We analyzed trajectories from compensated advanced chronic liver disease (cAC...