The University of Sydney

Are Group Interventions Effective at Improving Health Outcomes in Culturally And Linguistically Diverse (CALD) Populations With Chronic Conditions? An Umbrella Review

Abstract Culturally and linguistically diverse (CALD) populations experience disproportionate burdens of chronic disease compared to the general population; previous research demonstrated group-based interventions improve health outcomes across various chronic conditions. This um...

Efficacy of D-Mannose in the Management of Urinary Tract Infections: From Acute Treatment to Long-term Prophylaxis — A Systematic Review and Meta-analysis

Purpose: To evaluate the efficacy of D-mannose for preventing recurrent urinary tract infections (UTIs), including in kidney transplant recipients, and to clarify discrepancies between early openlabel and placebo-controlled trials.Materials and Methods: PubMed, Embase, CENTRAL (C...

What have we learned about Australia’s swampy meadows? a literature review

Abstract Scientists coined the term ‘swampy meadows’ over thirty years ago to describe a type of low-energy, discontinuous watercourse found in the valley fills of Southeastern Australia. Swampy meadows are believed to provide important ecosystem services, such as wildlife conser...

Mapping spatiotemporal soil temperature using physics-informed neural networks with the heat transfer equation

Soil temperature (ST) plays a critical role in regulating biogeochemical processes in soils, yet its spatiotemporal mapping remains a challenge. Existing ST maps are largely derived from land-surface models and are typically available only at coarse spatial resolutions, limiting...

Purpose-built WAAM 316L benchmark walls for thermo-mechanical calibration and strain-based hardness prediction

Wire Arc Additive Manufacturing (WAAM) of 316L generates complex thermal cycles, distortion and work hardening that are difficult to validate in 3D. Hence, in this paper, we design, build and fully characterise two benchmark walls (two-layer and three-layer) expressly for calibra...

HITH4HIPs: a feasibility trial of hospital in the home after hip fracture

In Australia, as in many other jurisdictions, people with low-trauma hip fractures often stay in hospital for extended periods, even when medically stable, increasing risk of hospital-related complications and increasing healthcare costs. In this context, we sought to determine t...

Cultural determinants and strategic priorities for medication safety in acute care: a multidisciplinary Delphi study

Abstract Background Organisational culture, defined as the shared values, assumptions, and norms that influence behaviour within organisations, is widely recognised as a key determinant of patient safety in healthcare systems. Within acute care settings, medication safety represe...

Resection Margin Status, Recurrence Pattern, and Salvageability After Resection for Colorectal Liver Metastases

Abstract Background The prognostic significance of margin status after colorectal liver metastases (CRLM) resection remains debated in the era of effective systemic therapy. This study examined the prognostic meaning of microscopically positive (R1) margins, focusing on recurrenc...

Cognitive Behavior vs Bright Light Therapy for Insomnia in Women Undergoing Chemotherapy for Breast Cancer

Importance Women receiving chemotherapy for breast cancer experience insomnia and fatigue, which impair quality of life. To date, no randomized clinical trial (RCT) has evaluated the use of cognitive behavior therapy for insomnia (CBT-I) and bright light therapy (BLT) both alone...

dioscRi enables transferable prediction of clinical outcomes in multi-parameter cytometry data

Abstract Multi-parameter cytometry technologies enable high-dimensional analysis of immune cell populations at single-cell resolution. Deep learning has emerged as a transformative tool for analyzing these datasets, but existing methods often struggle with transferability across...

The effect of augmented protein intake on nitrogen balance: A nested cohort study of the TARGET protein trial

Purpose The impact of augmenting enteral protein delivery on nitrogen balance, urea generation, and kidney function in critically ill patients remains poorly defined. This study aimed to investigate these effects in a nested cohort within the TARGET Protein trial. Methods We cond...

Compassion in Mental Health Nursing: A Scoping Review

Compassion is widely recognised as a core component of mental health nursing, yet its meaning and application within this specialty remain underexplored. This scoping review examined how compassion is conceptualised, experienced, and enacted in mental health nursing practice, and...

Prevalence of Healthy Eating Initiatives in Australian Primary Schools: A Cross‐Sectional Survey

ABSTRACT Issue Addressed Schools are recommended settings for promoting healthy eating, but to achieve population‐level impact, initiatives must be widely implemented. Limited data are available to assess the implementation of Australian school‐based healthy eating initiatives. T...

Modeling the influences of non-local connectomic projections on geometrically constrained cortical dynamics

The function and dynamics of the cortex are fundamentally shaped by the specific wiring configurations of its constituent axonal fibers, also known as the connectome. However, many dynamical properties of macroscale cortical activity are well captured by instead describing the ac...

Why sexual violence and harassment are not addressed: comparative insights from Cambodia's construction sector

Purpose This article assesses whether workplace formality determines how sexual violence and harassment (SVH) complaints are interpreted, understood and addressed by workplace intermediaries in three cement factories and on 39 construction sites in Cambodia. Design/methodology/ap...

Effects of mandibular advancement device versus continuous positive airway pressure on cardiac remodeling in obstructive sleep apnea: a randomized CMR substudy

Obstructive sleep apnea (OSA) is associated with adverse cardiac remodeling, including diffuse myocardial fibrosis. Continuous positive airway pressure (CPAP) is the standard treatment for OSA, while mandibular advancement devices (MAD) may represent an alternative. However, thei...

Concentrations of polychlorinated biphenyls and toxic metals in short-tailed shearwaters following a mass mortality event

In 2013, a mass mortality event resulted in the deaths of approximately three million short-tailed shearwaters ( Ardenna tenuirostris ) along the east coast of Australia. As pelagic apex predators within their marine ecosystems and extensive migratory routes, these seabirds may s...

A serum protein–to–bilirubin ratio predicts immune-mediated hepatotoxicity in lung cancer patients treated with immune-checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) have transformed outcomes for patients with advanced non-small cell lung cancer (NSCLC) but are associated with immune-related adverse events, including hepatotoxicity. Immune-mediated liver injury can necessitate treatment interruption and imm...

Integration of lipidomic and polygenic risk scores within contemporary clinical cardiovascular risk assessment pathways: a multi-cohort development and validation study

Background Guideline-recommended clinical risk scores such as AusCVDRisk underestimate cardiovascular disease (CVD) risk in a substantial proportion of individuals who later experience events, with up to 65% initially classified as low or intermediate risk. This limitation is mos...

Unlock the Potential of Pichia in Coffee: Knowledge Transfer From Fermented Beverages

ABSTRACT Considerable research has focused on non‐ Saccharomyces yeasts to explore their biochemical potential and genetic diversity beyond the capabilities of the conventional starter culture, Saccharomyces cerevisiae . Among these, species of the genus Pichia have emerged as pr...