The University of Sydney

Anatomical and Histologic Response to Neoadjuvant Therapy: Recurrence Patterns Among Poor Responders. A Multi-institutional Observational Cohort Study.

OBJECTIVE: To characterize the prognostic implications after hepatectomy for colorectal liver metastases (CRLM) by integrating anatomical response to neoadjuvant therapy (NAT), quantified using the Tumor Burden Score ratio (TBSr), with histologic response assessed by Tumor Regres...

SCANNER: A Deep-Learning System for Detecting the Digital Marketing of Foods and Beverages.

. 2026;116(10):1557-1564. https://doi.org/10.2105/AJPH.2026.308700).

A multicenter multistate modeling on the natural history of liver decompensation: Longitudinal analysis of 1777 patients.

BACKGROUND: Cirrhosis often remains silent until decompensation, after which survival deteriorates sharply. Contemporary, transition-aware estimates are limited, especially in Asian-predominant cohorts. We analyzed trajectories from compensated advanced chronic liver disease (cAC...

The lived experience of trans persons: a bottom-up review co-written by experts by experience and academics.

We present here the first bottom-up review of the lived experience of trans persons, co-written by experts by experience and academics. We sourced the medical and non-medical literature, focusing on first-person narratives, and critically extracted experiential themes, which were...

Spatial variability in seawater chemistry across an intertidal mangrove–coral reef boundary

Context Edge effects at habitat boundaries can generate strong physicochemical gradients that structure coastal ecosystems. Although environmental gradients within coexisting mangrove–coral habitats are well documented, spatial variability in seawater chemistry across intertidal...

Precision Protein Modification via Ligation and Bioconjugation at Selenocysteine

Conspectus Selenocysteine (Sec), often referred to as the 21st amino acid, is a rare yet essential amino acid found in a small number of naturally occurring selenoproteins that play critical roles in redox regulation, antioxidant defence, and hormone metabolism. Owing to its dist...

Hamstring Strain Grade on MRI and Return to Play in Elite Australian Cricket Players

OBJECTIVE: The aims of this study were to (1) examine the relationship between magnetic resonance imaging (MRI)-confirmed hamstring strain grade and time to return to play; (2) examine this relationship specifically in pace bowlers; and (3) describe the incidence, prevalence, and...

Surgical outcomes of trabecular micro-bypass minimally invasive glaucoma surgery devices in eyes with high myopia: a 24-month retrospective multicenter cohort study

BACKGROUND: To describe outcomes of two trabecular bypass minimally invasive glaucoma surgery (MIGS) devices in highly myopic (HM) eyes with glaucoma up to 24 months postoperatively. METHODS: A retrospective, observational multicenter study of HM eyes (phakic refractive spherical...

Heritability of Fruit and Vegetable Consumption and Depressive Symptoms in Community-Based Middle-Aged and Older Adults from Four International Twin Cohorts

Fruit and vegetable intakes have been associated with reduced risk of depressive symptoms in observational studies, potentially due to anti-inflammatory properties, micronutrient content, and effects on the gut-brain axis. Understanding the genetic and environmental influences on...

Energy value of cereal grains for broiler chickens. I. Variation within and among grain species, and effect of exogenous enzymes

Context Cereal grains are the major source of energy for broiler chickens. Energy available to chickens varies widely within and among cereal species and must be measured to develop near-infrared (NIR) calibrations for predicting values when formulating diets. Aims To measure app...

Corticosteroid use in children with community acquired sepsis: a multicentre prospective cohort study

Objectives Corticosteroids in paediatric sepsis have the potential to improve outcomes, yet there is little supporting evidence regarding efficacy, choice of agents, dose or timing of administration. We describe the patterns of corticosteroid use in children hospitalised with sus...

Knowledge and attitudes about artificial intelligence and its applications among Chinese endodontic practitioners: a cross - sectional survey

Artificial intelligence (AI) has been increasingly applied in dentistry, including cariology and endodontics. However, evidence remains limited regarding endodontic practitioners’ AI literacy, perceptions, clinical usage, and barriers to AI integration. This study aimed to invest...

Energy value of cereal grains for broiler chickens. III. Suitability of NIR for predicting AME of wheat for diet formulation

Context Cereal grains vary widely in energy content, which can result in poor performance of chickens when wrongly assumed apparent metabolisable energy (AME) values are used in diet formulation. Aims To evaluate the suitability of using near-infrared spectrometry (NIR) calibrati...

Sex and Mortality Among Patients with Papillary Thyroid Cancer

Importance Unlike patient age, which has been a well-established and routinely used primary biological prognostic factor in the risk stratification of papillary thyroid cancer (PTC), the prognostic value of patient sex remains controversial in this common endocrine malignant neop...

Comprehensive profiling of brain dynamics during anesthesia across phylogeny

Abstract The behavioral effects of anesthetics are highly conserved across species, hinting at shared and fundamental underlying mechanisms. Here we compile a dataset of multiscale neural activity during wakefulness and anesthesia, encompassing human, macaque, marmoset, mouse, ze...

Phototherapy Strategies for Cancer Treatment: Mechanisms and Emerging Nanomaterials

ABSTRACT Phototherapy has become a significant research direction in tumor therapy owing to its high spatial selectivity, low systemic toxicity, and excellent biocompatibility. In recent years, diverse strategies including photodynamic therapy (PDT), photothermal therapy (PTT), p...

A multidisciplinary perspective on digital health interventions in schizophrenia care: Expanding the 2026 Grading of Recommendations, Assessment, Development and Evaluations guidelines

In this paper, we aim to provide a multidisciplinary and lived-experience-informed perspective on existing evidence for the utilisation of digital health interventions in schizophrenia care. We have integrated the findings from the most recent meta-analysis of digital health inte...

Body Weight in Relation to the Effectiveness of Intravenous Alteplase in Acute Ischemic Stroke: The ENCHANTED Trial

BACKGROUND: The prognostic significance of body weight in patients receiving thrombolysis for acute ischemic stroke remains uncertain. This study aimed to determine whether body weight modifies the comparative effects of low- versus standard-dose intravenous alteplase and to eval...

Full‐Field Damage Monitoring in Architected Lattices Using In situ Electrical Impedance Tomography

ABSTRACT Electrical impedance tomography (EIT) enables non‐invasive, full‐field reconstruction of conductivity distributions, providing distributed sensing beyond point measurements. Here, we demonstrate the first in situ implementation of EIT in tunable architected lattice mater...

Lightweight Relation-Aware Graph Neural Networks for Network Threat Detection in the Social Internet of Things

Network threat detection in the Internet of Things must exploit typed relations between devices: a device with unremarkable flow statistics may still be compromised relative to its ownership, co-location, and social ties. Existing graph-based intrusion detectors discard relation...