The University of Sydney

Increasing humidity progressively reduces sweating efficiency similarly in males and females during exercise-heat stress

This study compared the impact of increasing relative humidity (RH) on sweating efficiency (SE) in males and females exercising in the heat. Twenty recreationally active adults (10 females) completed four experimental trials (15, 35, 55, or 75% RH) in an environmental chamber (35...

Language impairments in behavioural variant frontotemporal dementia: a comparative study with semantic dementia

Abstract Introduction Recent evidence suggests that individuals with behavioural variant frontotemporal dementia (bvFTD) may experience language changes in a similar, but less severe manner, than what is observed in semantic dementia (SD). Few studies, however, have specifically...

Temporal frictions in Australian horticultural value chains: Nature's time, power asymmetries and environmental consequences

The interdisciplinary agrifood literature has paid significant attention to power imbalances between supermarkets and suppliers, identifying fresh produce growers as particularly vulnerable to exploitative procurement practices. However, less work has examined the temporal charac...

Partitioning secreted sweat in the measure of sweating efficiency during exercise

Sweating efficiency (SE), defined as the proportion of total secreted sweat that evaporates from the body, is a critical determinant of evaporative heat loss and fluid requirements during exercise. Despite its physiological importance, direct assessments of evaporated sweat loss...

Oxygen minimum zones in the Indian Ocean and their response to changes in the Indian Ocean meridional circulation

Abstract. The Oxygen Minimum Zones (OMZs) in the northern Indian Ocean (i.e., the Arabian Sea and the Bay of Bengal) are among the most intense OMZs in the world's oceans. While there has been no clear evidence of a significant change in the Bay of Bengal OMZ (BoB OMZ), the Arabi...

Modular Transformations of Tau Functions and Conformal Blocks on the Torus

Abstract The connection problem for isomonodromic tau functions on the one-punctured torus concerns the ratio between the tau function and its modular transform, associated to dual pants decompositions of the torus. In this paper, we study the modular transformations of the tau f...

The Association of Umbilical Cord Blood Neurofilament Light With Nonreassuring Fetal Status: A Prospective Observational Study

( Int J Gynaecol Obstet . 2026 Mar;172(3):1491–1500. doi:10.1002/ijgo.70421) A prospective observational study explored whether neurofilament light (NfL), a marker of neuronal injury, can be reliably measured in umbilical cord blood and whether it is associated with nonreassuring...

Extended dispensing intervals for pancreatic enzyme extract without access destabilisation: a national retrospective study evaluating supply resilience during policy changes and medicine shortages in Australia

OBJECTIVE: This study aims to describe national trends in pancreatic enzyme replacement therapy (PERT) dispensing in Australia and assess changes following the introduction of 60-day prescription dispensing, in the context of medicine shortages and market changes. METHODS: Public...

Regime Shifts and Transformations in Social-Ecological Systems: Advancing Critical Frontiers for Safe and Just Futures

Current research challenges in sustainability science require us to consider nonlinear changes—shifts that do not happen gradually but can be sudden and difficult to predict. Central questions are therefore how we can prevent harmful shifts, promote desirable ones, and better ant...

Model 1b analytical performance specifications – report on the Prague 2025 workshop

diagnostic medical devices (IVD MD) meet regulatory and quality standards before market release; for external quality assurance assessments; for quality control, monitoring reagent lot-to-lot variability, and allowing preanalytical variation assessments in labs; and for guiding p...

Following the rules: which type 1 diabetes guidelines, protocols and recommendations are tertiary clinics in Australia following? A quantitative study

OBJECTIVES: This study characterises the use of type 1 diabetes (T1D) guidelines and protocols in Australian T1D clinics working with paediatric patients, and determines if management practices align with T1D-specific guidelines. METHODS: T1D clinic service leaders responded to a...

Factors Associated with Extreme Waiting Times for Child Developmental Diagnostic Assessments: A Mixed-Methods Service Evaluation in Sydney

Background: Previous Australian child developmental assessment service (CDAS) cohorts have identified a small proportion of children experiencing extreme waiting times (≥730 days) for standardised developmental assessments. However, factors associated with these extreme waits rem...

A multi-centre study of belatacept and sirolimus for islet transplantation

Abstract Aims/hypothesis Islet transplantation is an appropriate treatment for selected individuals with type 1 diabetes mellitus and hypoglycaemia unawareness. The gold standard of maintenance immunosuppression to prevent allograft rejection is calcineurin inhibitor-based therap...

Can artificial intelligence improve precision dosing? a systematic review of narrow therapeutic index drugs

Abstract Background Precision dosing of narrow therapeutic index drugs remains challenging because of substantial interindividual variability and the narrow margin between therapeutic efficacy and toxicity. Artificial intelligence (AI)–based approaches may improve individualized...

End-of-life planning and its governing policies: a comparison of New South Wales public health facility documents

OBJECTIVE: This desktop/scoping document review aimed to determine differences in availability, content, definitions, and terminology used in NSW Health policy documents that pertained to end-of-life planning. METHODS: A desktop/scoping comparative analysis of identified document...

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Peptide binders provide a versatile modality for modulating protein targets that are poorly addressed by small molecules, but their discovery is constrained by sample-intensive screening or reliance on structural templates. Sequence-first generation offers a scalable alternative...

Hyperbolic confinement: self-assembly of asymmetric diblock co-polymers on triply periodic minimal surfaces

Abstract We investigate the self-assembly of compositionally asymmetric AB diblock co-polymers confined to thin hyperbolic films on the three cubic minimal surfaces: the primitive, the diamond and the gyroid. To analyse and quantify the assemblies, we use a computational pipeline...

Effect of Testosterone Treatment on Leucocyte Telomere Length in Men: Results From a Randomised Placebo‐Controlled Trial

BACKGROUND: Lower testosterone concentrations in older men are associated with poorer health outcomes. OBJECTIVE: We examined whether, on a background of lifestyle intervention, testosterone treatment modulates leucocyte telomere length, a postulated marker of biological ageing,...

Upward single-nozzle sprays: Droplet count, size, and velocity under flash pressures with directional conditional filtering

This study investigates the influence of pressure variation on droplet characteristics (count, size) and dynamics (velocity) in upward atomised full-cone sprays. The challenges of understanding the fundamental droplet behaviour in spray-flash desalination systems further imposes...

Seeing Inequalities: Self-Reported Visual Difficulty and Eye Care Utilization Among Women in Malawi, a Secondary Analysis of the 2024 Demographic and Health Survey Data

Background: This study aimed to identify the factors associated with self-reported visual difficulty and uptake of spectacle/contact lens correction among women of reproductive age in Malawi. Methods: We conducted a cross-sectional secondary analysis of the 2024 Malawi Demographi...