Institution
Stanford University
Recent research
- Health & Medicine
O.L. is a named inventor on patents held by Boston Children's Hospital related to vaccine adjuvants and antigens as well as human in vitro systems that model the safety and immunogenicity of vaccines and immunotherapeutics. O.L.’s laboratory receives sponsored research support fr...
- Health & MedicineOpen access
Abstract Background Anterior clinoid meningiomas (ACM) and tuberculum sella meningiomas (TSM) are anterior skull base tumors that commonly cause visual deterioration. The supraorbital keyhole approach may be used to resect these tumors but is limited by restricted intraoperative...
- Health & MedicineOpen access
Abstract Objective Emergency care (EC) utilization can indicate unmet medical or social needs. In pregnancy, EC use may identify individuals at risk for adverse outcomes and highlight opportunities for intervention. This study examined the association between EC use in early preg...
- AI & Computing
Bias in Cohort Studies: The Critical Importance of the “Why” and “When” of Treatment Decisions
When it comes to high-quality, rigorous research, children generally get the short end of the stick. Randomized controlled trials (RCTs)—the “gold standard” for clinical research1—are rare in this population.2 RCTs are expensive, time-consuming, and often fraught with ethical con...
- Health & Medicine
ABSTRACT Restoring three‐dimensional electrical conduction in infarcted myocardium remains a critical challenge, as conventional conductive hydrogel patches largely remain surface‐confined and prevent electrical coupling of residual cardiomyocytes within fibrotic scars. Here, we...
- Engineering & TechnologyOpen access
The Biomimetic Sampler: A Constraint-Based Ideation Exercise for Introductory Biodesign Education
Abstract This demo presents the Biomimetic Sampler: a constraint-based ideation exercise that introduces participants to foundational concepts of biodesign through two linked activities, observation and translation, conducted under time pressure. The exercise requires no prior ba...
- Physics & SpaceOpen access
Time-resolved imaging of antiferromagnetic skyrmion interactions
Abstract Quantifying particle interactions is central to understanding and controlling collective dynamics in particle-based devices such as those comprising skyrmion ensembles. Here we directly visualize, in real time, the nanosecond current-driven dynamics of an antiferromagnet...
- Health & Medicine
Price comparisons for the leading brands of oral nicotine pouches and cigarettes
Abstract Background and aims United States (US) sales of oral nicotine pouches (ONPs) more than tripled from 2021 to 2024, with Zyn brand consistently the market leader. To understand the relative price of ONPs and cigarettes, this study answers three questions about differences...
- Engineering & Technology
Solvent-Mediated Diffusion Enables Directed Functionalization of Polymer Semiconductor Interfaces
The increasing interest in the development of intrinsically stretchable electronic devices based on polymer semiconductors (PSCs) necessitates a comprehensive understanding of the interfacial chemistry of these PSC films, alongside facile processing methods to modify these proper...
- BiologyOpen access
An Intrinsic Formula for the Ray–West Correction Term
For a nonempty permutation β of length m, Ray and West expressed the number of length-(m+2) permutations containing β using a correction term j(β), but did not give j as a statistic intrinsic to β. This is Problem 3.7 of Vatter’s 2026 survey. This preliminary technical report pro...
- BiologyOpen access
An Intrinsic Formula for the Ray–West Correction Term
For a nonempty permutation β of length m, Ray and West expressed the number of length-(m+2) permutations containing β using a correction term j(β), but did not give j as a statistic intrinsic to β. This is Problem 3.7 of Vatter’s 2026 survey. This preliminary technical report pro...
- Climate & EnvironmentOpen access
Grinding en route to sedentism: Plant processing in the 8 ka-BP southern Mongolian Plateau, China
Plant food exploitation has long been considered one of the most significant windows to understanding the process of sedentism. Two early Neolithic sites, Yumin (ca. 8,400-7,600 cal BP) and Simagou (ca. 7,500-7,000 cal BP), witnessed the earliest onset of a sedentary lifeway in t...
- Engineering & TechnologyOpen access
Trions as Fundamental Species in Chemically Doped Polymer Semiconductors
Doping is a cornerstone strategy for enhancing charge transport in semiconducting polymers, important for their application in, for example, semi-transparent electrode materials, thermoelectric devices, and antistatic coatings. Both chemical and electrochemical doping have, for t...
- Engineering & Technology
A Skin‐Inspired High‐κ Self‐Healing Polymer for Low‐Voltage Dielectric Elastomer Actuators
ABSTRACT Dielectric elastomer actuators (DEAs), known as a type of artificial muscles, are promising soft actuators with many applications including robotics and wearables due to their conformability, fast response, and large actuation. However, their usage remains constrained by...
- Biology
Robust Inference With Ghostknockoffs in Genome‐Wide Association Studies With Sample Relatedness
ABSTRACT Genome‐wide association studies (GWASs) have been extensively adopted to depict the underlying genetic architecture of complex traits. Recent studies show that knockoff‐based methods can identify variants with unique, potentially causal effects on phenotypes. However, th...
- BiologyOpen access
Abstract Type 2 diabetes mellitus (T2D) increases the risk of atherosclerotic diseases, including coronary artery disease (CAD), but decreases that for abdominal aortic aneurysm (AAA), forming an intriguing diabetes-atherosclerosis paradox. We investigate how genetic underpinning...
- Physics & SpaceOpen access
Optical isolation and circulation using quantum frequency conversion on a chip
Breaking electromagnetic reciprocity enables directional control of light and is essential for both classical and quantum photonic systems. However, realizing integrated optical nonreciprocity that simultaneously combines low loss, broad bandwidth, and compatibility with quantum...
- BiologyOpen access
Community metabolism in dynamic redox landscapes
Microbial communities are fundamentally shaped by the diverse metabolic processes through which microbes extract energy from the chemical and light-driven potential gradients in their environment. Thus, predicting microbial community dynamics requires a quantitative framework gro...
- BiologyOpen access
Abstract: Regulatory DNA contains sequence elements that guide transcription factor (TF) binding and chromatin accessibility, that in turn control the expression of nearby genes. Most current descriptions of such regulatory elements are based on classical, statistical enrichment-...
- Health & Medicine
Resident Perspectives on Post-Rounds Communication With Families Using Diverse Languages
OBJECTIVE To explore pediatric residents’ experiences communicating with families after rounds and identify barriers and facilitators to communication with families using languages other than English (LOE). METHODS We conducted a qualitative study using semi-structured interviews...