Shanghai Jiao Tong University

CELLServe: An SLO-Aware and Cost Efficient LLMs Serving System for Serverless Computing Environments

Large Language Models (LLMs) have enabled diverse AI applications. However, LLMs inference impose unprecedented computational and memory overhead, creating an inherent trade-off between latency Service Level Objectives (SLOs) and resource constraints. Serverless computing, with o...

Real-world evidence of self-managed weight loss enhancing skeletal muscle rate in individuals with overweight/obesity via mHealth app

Weight loss is essential for obesity management but may be compromised by skeletal muscle loss. This study evaluated the increase in skeletal muscle rate (SMR) and fat loss among individuals with overweight/obesity who achieved weight loss through self-management using a mobile h...

Xtream: A Production-Level VM Cross-Cloud Disk Migration System with Stripe-Oriented Prefetching

Virtual machine (VM) cross-cloud migration refers to the transfer of VMs between different cloud environments, enabling users to deploy their business with greater flexibility. However, VM cross-cloud migration faces many challenges in production due to the high latency and limit...

AnEnergy-Sustainable and Oxidative-Tolerant Nanofactoryof Therapeutic Proteins for Long-Acting Therapy of Inflammatory BowelDisease

Abstract The ability to continuously generate bioactive therapeutics at the diseased site is an appealing and crucial advantage for the treatment of chronic relapsing diseases such as inflammatory bowel disease (IBD). Current in situ therapeutic factory strategies mainly rely on...

Architecting optimized heterostructure for exceptional strength-ductility synergy in Mg-Gd-Y-Zn-Mn alloy

Achieving a superior combination of strength and ductility in magnesium (Mg) alloys remains challenging. Heterogeneous microstructures have been demonstrated as an effective strategy to overcome this dilemma. In this study, a remarkable strength-ductility synergy is sustained in...

Wintertime organic carbon export provides a potential food source for zooplankton in the High Arctic

Abstract Pulsed particulate organic carbon export plays a vital role in sustaining Arctic marine ecosystems and the biological pump. Wintertime particulate organic carbon export in ice-covered Arctic waters is generally considered negligible due to light-limited local primary pro...

AI-Assisted Viable Digital Array for Rapid Quantification of Bacteria in Pediatric Urinary Tract Infections

Abstract Urinary tract infections (UTIs) are among the most common bacterial infections in neonates and infants, and delayed diagnosis can lead to severe complications. Rapid, quantitative detection of viable bacteria at the point of care remains a critical unmet need. Here, we p...

Bioinspired Large-AreaPolymeric Cucurbituril Monolayerswith Ultrahigh-Density Nanopores Enabling Reversible Charge-Gatingof Ion Transport via Host–Guest Recognition

Abstract Achieving precise control over ion and molecular transport under subnanometer confinement, especially beyond passive sieving, remains challenging in nanofluidics and membrane science. Here, we present a bioinspired strategy that enables the formation of subnanometer chan...

Advancing Energy Efficiency in Smart Windows via Dual‐Responsive Electro‐Thermochromism

ABSTRACT Implementing dynamic smart windows is imperative toward the construction of net‐zero buildings. However, the prevailing ion (de‐)embedding‐based electrochromic (EC) or thermosensitive hydrogel‐based thermochromic (TC) windows fail to achieve large optical modulation acro...

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

ABSTRACT Diabetic foot ulcers are a major complication of diabetes characterized by persistent inflammation and impaired tissue repair, in part driven by aberrant activation of the cGAS‐STING innate immune pathway. Precision immunomodulation in the protease‐rich wound microenviro...

An N-acetylated daropeptide modulates nematode development

The symbiotic bacterium Photorhabdus is a rich source of bioactive secondary metabolites that mediate tripartite interactions with nematodes and insect hosts. However, natural products of ribosomal origin remain largely underexplored within this ecological niche. Here, we report...

A transposon-derived transcription factor senses ionic stress through phase separation to govern plant autophagy

Salt stress severely impairs plant growth through two distinct cellular insults: osmotic stress caused by water limitation and ionic toxicity resulting from excessive Na + accumulation. Although plant osmosensors have been identified, the mechanisms underlying ionic stress percep...

Natural Sunlight IR‐Driven Highly Efficient Synthesis of Acetaldehyde From Bioethanol Over Cu/Fe 2 O 3

ABSTRACT Using renewable biomass to synthesize valuable chemicals can reduce fossil fuel dependence and achieve carbon neutrality. Here, for the first time an infrared light‐driven catalyst, Cu/Fe 2 O 3 , was designed to convert bioethanol to valuable acetaldehyde, accompanied by...

State-dependent reconfiguration failure of the basal forebrain-cortical gradient in Parkinson’s disease with freezing of gait

Accumulating evidence implicates cholinergic dysfunction in freezing of gait (FOG) in Parkinson’s disease (PD). Given the basal forebrain (BF) provides the primary cholinergic input to the cortex, elucidating BF-cortical connectivity and its dynamic reconfiguration during motor c...

IntegratedCRISPR/Cas12a-Based Duplex Detection Platformfor Species Fingerprinting

Abstract Species fingerprinting is crucial to ensure food safety and human health, which requires a rapid, simple, multiplex, and field-deployable detection technique. In response, a lab-on-a-disc microfluidic chip with CRISPR/Cas12a that integrates target preamplification and si...

Synergy Between Air Pollution and Carbon Emissions of On-Road Mobile Sources, Evidence from a Typical Southwestern Region in China

The transport sector has emerged as a significant source of greenhouse gases and airborne pollutants. However, few studies have carried out a comprehensive assessment of the synergistic benefits between air pollutant and carbon emission reductions that account for the unique regi...

Are Higher Medical Benefits Associated with Fertility Intentions?—A Survey Study from the Yangtze River Delta Region

Objectives: The aging population problem caused by low fertility intentions has already emerged worldwide and is expected to become more severe in the future. Despite the gradual implementation of welfare policies, there has been no substantial improvement in individuals’ intenti...

Surgical treatment of pancreatic cancer in China: Annual data report of China Pancreas Data Center (2020–2021)

Abstract Objective: The China Pancreas Data Center (CPDC) was established in 2015 with the support of the Chinese Pancreatic Surgery Association, Chinese Society of Surgery, Chinese Medical Association and initiated prospective data collection in 2017. This article reports contem...

Three-Dimensional Physics-Based Circuit Modeling of Battery Incipient Faults in Microgrid Applications

Battery condition directly affects the reliability, resilience, and safety of microgrids, making physically interpretable battery information an important input to situation awareness. In practical microgrid operation, battery monitoring commonly relies on terminal signals availa...

NDUFV1 activation mediates high glucose-induced apoptosis in peritoneal mesothelial cells

Peritoneal mesothelial cells (PMCs) are critical components of the peritoneum, and prolonged exposure to high glucose in peritoneal dialysis fluid can lead to structural and functional impairment of the peritoneal membrane. However, whether such cellular damage is caused by gluco...