Shanghai Jiao Tong University

Development and application of a smartphone-based thermal contrast amplification reader for photothermal lateral flow immunoassays

The high cost and poor portability of external infrared thermal imagers have limited the widespread adoption of photothermal lateral flow immunoassays (PT-LFIAs) in on-site testing. To address this, we developed a smartphone-based handheld Thermal Contrast Amplification (TCA) Rea...

Dependence of mechanical properties on microstructural partitioning driven by non-uniform rare-earth distribution in laser-CMT hybrid welded Mg-Al-Zn alloy

The insufficient mechanical properties in welded magnesium alloy joints, which are inherently due to weak metallic bonds, pose a considerable challenge that restricts their widespread application in lightweight aircraft structures. This paper focuses on the enhancement of mechani...

Persistent Hypoperfusion on Post‐Recanalization Digital Subtraction Angiography Perfusion Maps in Anterior Circulation Large Vessel Occlusion

Background Despite high recanalization rates with endovascular thrombectomy for large vessel occlusion stroke, a large proportion of patients remain disabled. This study aims to investigate the clinical impact of persistent hypoperfusion that was detected immediately after recana...

Unveiling Carrier‐Mediated Acoustic Leakage as a Hidden Loss Pathway in Piezoelectric‐Semiconductor Heterostructures

ABSTRACT Heterogeneous integration of dissimilar functional materials enables advanced micro/nano devices with unprecedented functionalities, yet the resulting interfacial multiphysics interactions can introduce hidden energy leakage pathways beyond conventional bulk systems. Her...

CNT-Mediated Integration of Pd and In2O3 Circumvents Activity–Stability Trade-Off in CO2 Hydrogenation to Methanol

Abstract Metal promotion is a widely adopted strategy to enhance the activity of indium oxide (In2O3) catalysts for CO2 hydrogenation to methanol. However, intimately contacted metal promoters on In2O3 often result in rapid catalyst deactivation, as excessive local H2 supply indu...

Prototype-Guided Test-Time Adaptation for Real-Time EMG-Based Gesture Recognition

Surface electromyography (sEMG) signals facilitate intuitive human-machine interaction and are widely employed in applications such as prosthetics and rehabilitation. However, sEMG signal distributions are highly sensitive to variations in electrode placement, user physiology, an...

PET imaging enables direct evaluation of ferroptosis in HCC synergistically induced by anti-PD-L1 and Olaparib

Abstract The efficacy of PET image-guided immune checkpoint inhibitor-based therapy in hepatocellular carcinoma (HCC) management is limited by the lack of direct monitoring of therapeutic response. A key challenge is the mismatch between the therapeutic pathway and the imaging ta...

PD-L1-Targeted and ROS-Responsive Nanoplatform for Simultaneous Chemotherapy and Dual-Modal Imaging of Treatment Response in Triple-Negative Breast Cancer

Abstract The evaluation of treatment response in triple-negative breast cancer (TNBC) still primarily relies on tumor size and ex vivo analyses, which provide very limited information on how tumors dynamically respond during therapy. In fact, oxidative stress rapidly emerges earl...

Interpretability-enhanced temporal surrogate modeling for wave-induced scour vulnerability assessment of vertical-wall structures

Scour compromises the stability and safety of vertical-wall structures, necessitating a systematic method to assess scour vulnerability. However, two key vulnerability elements remain unresolved, namely suitable grading thresholds and an efficient temporal scour surrogate model....

Structure-Acoustic Coupling Analysis of Underwater Acoustic Radiation Characteristics of a Multiple Intersecting Spherical Shell Under Acoustic Excitation

The underwater acoustic radiation of deepwater submersibles has become a growing concern in both academic and industrial communities. This study investigates the structure-acoustic coupling characteristics of a novel deepwater pressure hull, idealized as a triple spherical shell....

Lattice-Oxygen-Mediated Electronic Reconstruction of High-Entropy Oxides for Durable Fenton-like Water Treatment

Abstract High-entropy catalysts offer broad compositional tunability for peroxymonosulfate (PMS)-based water treatment, yet achieving rapid, selective, and durable oxidation remains challenging because metallic bonding in high-entropy alloys (HEAs) limits electronic communication...

Public perception of food safety governance and its influencing factors and research trends

Food safety governance has become increasingly important in public health and social governance, yet improvements in formal regulatory systems do not necessarily translate into more positive public evaluations. This integrative review synthesizes multidisciplinary evidence on pub...

Advances in functional nanomaterial interfaces for small-molecule metabolite sensing and wearable applications

Dynamic metabolic changes provide functional information that cannot be captured by a single laboratory test, necessitating repeated biochemical measurements of accessible biofluids. Wearable platforms offer a practical route for repeated or continuous monitoring, whereas nanomat...

CD24 blockade reprograms macrophages and synergizes with CD47 blockade to overcome tumor immune evasion

Although immunotherapy has revolutionized cancer treatment, only a minority of head and neck squamous cell carcinoma (HNSCC) patients derive clinical benefit, underscoring the urgent need to uncover novel immune evasion mechanisms. CD24 serves as a pivotal innate immune checkpoin...

Dynamic Root-Zone Temperature Regulation Enhances Cherry Tomato Productivity Through Coordinated Root and Leaf Responses

Low and fluctuating root-zone temperatures constrain tomato productivity during winter greenhouse cultivation, yet the advantages of dynamic regulation over fixed-temperature control remain unclear. In this study, cherry tomato plants were subjected to an unregulated control (CK)...

PCR: A Prefetch-Enhanced Cache Reuse System for Low-Latency RAG Serving

Retrieval-Augmented Generation (RAG) significantly improves Large Language Models (LLMs) but introduces massive input sequences that severely bottleneck the prefill stage. While KV-cache reuse reduces redundant computation for shared document prefixes, the reusable KV working set...

Clinical management of relapse in type 1 autoimmune pancreatitis: a systematic review and meta-analysis

Objectives: Type 1 autoimmune pancreatitis (AIP) has a high risk of relapse, but evidence to guide management is limited. We evaluated relapse patterns, predictors, and the comparative effectiveness of maintenance and relapse treatment. Methods: We systematically reviewed studies...

A Novel Umami Peptide Selector (UPS) for Identifying Key Peptides from Maillard-Reacted Chicken Hydrolyzates: From Taste Evaluation to Antioxidant Properties

Abstract The Maillard reaction (MR) enhances the flavor of chicken enzymatic hydrolyzates, yet pinpointing key umami peptides remains challenging due to complex matrices. Sensory evaluation showed increased umami intensity despite decreased equivalent umami concentration (EUC: 0....

Automatic Generation of Inorganic Solid‐State Electrolytes via Unified Multi‐Modal Network

ABSTRACT Accurate prediction of ion transport properties remains a key bottleneck in computational discovery of solid‐state electrolytes, particularly because experimentally measured ionic conductivities are sparse and strongly dependent on crystal structure. Here we introduce US...

Optimal inertia allocation in networked DC microgrids with guaranteed steady-state and small-signal stability

DC microgrids (MGs) are considered an efficient solution for integrating distributed energy sources. In these networks during dynamic power imbalances, the stored energy in the capacitor of DC bus provides the natural tendency to resist voltage changes, equivalent to the physical...