Shanghai Jiao Tong University

Home enteral nutrition management in postoperative oral cancer patients: an evidence summary

Abstract Background This study aimed to establish a standardized management system for home enteral nutrition (HEN) for patients with postoperative oral cancer and provide scientific guidance for clinical professionals by systematically searching relevant literature and summarizi...

Multi-objective and cross-scale inverse design of temperature-control materials via physics-constrained machine learning

Abstract Temperature-control materials, notably composite phase-change materials (CPCMs), show great potential for the thermal management of next-generation power electronics. However, the synergistic optimization of multiple performance metrics still relies heavily on Edisonian...

An Improved Method for Calculating the Radiative Cooling Heat Dissipation Power of an Oil‐Natural‐Air‐Natural Transformer

ABSTRACT Radiative cooling holds potential for outdoor transformers in operation due to its zero‐energy consumption and high adaptability and has demonstrated effective heat dissipation in simulations of small distribution transformers. Accurate calculation of the transformer tem...

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

ABSTRACT Antibody junctional diversity in jawed vertebrates arose from RAG transposon domestication, generating CDR3‐focused V(D)J recombination with lymphocyte specificity—a constrained system limiting engineered antibody diversity. To overcome these limitations, we developed AR...

Language-enhanced generative modeling for amyloid PET synthesis from MRI and blood biomarkers.

Assessment of amyloid pathology in Alzheimer's disease (AD) often relies on amyloid-beta positron emission tomography (Aβ-PET), but its clinical use is limited by cost and accessibility. We developed a language-enhanced generative framework to synthesize Aβ-PET images from T1-wei...

Diff-VF: Training-free High-quality Long Video Generation via Diffusion Model

Recently, diffusion models have made great progress in video generation. However, most existing video diffusion models are trained with short videos, and degrade when extrapolated to long videos, struggling to maintain long-range temporal coherence while retaining diverse motions...

Singular limit problems on the minimal travelling wave speed of the Lotka–Volterra competition model

Abstract We investigate singular limits of the minimal travelling wave speed in a Lotka–Volterra competition-diffusion system. We identify several singular regimes and determine the corresponding speed selection mechanisms. The main difficulty arises from the lack of monotonicity...

Topology-Driven Sodium Storage and Conversion in Covalent Fullerene Networks

Abstract Fullerene network is an emergent two-dimensional (2D) carbon allotrope in which C60 molecules are covalently bonded to form a quasi-hexagonal pattern (qHP). The intermolecular covalent bonding significantly reshapes the intrinsic electronic structure of the C60 units, le...

Does Test Duration Matter? Comparing 1‐s and 5‐s Isometric Mid‐Thigh Pull Protocols for Performance Diagnostics in Basketball Players

ABSTRACT To compare kinetic characteristics of a 1‐s isometric mid‐thigh pull (IMTP) protocol with the traditional 5‐s protocol and examine their associations with basketball‐specific performance. Twenty‐five Tier 3 male basketball players performed standardized 1‐s and 5‐s IMTP...

A numerical investigation on ultimate strength of marine sandwich composites under combined biaxial compression and lateral pressure

With the development of large-scale and light-weight ships, sandwich composites are increasingly used in hull structures because of their advantages of light weight, excellent mechanical properties, and corrosion resistance. Due to the synergistic effect among materials, sandwich...

Narrating for whom? Negotiating proper distance in sponsored narratives of therapeutic experiences in the platformized influencer economy

As online therapy services increasingly rely on social media platforms and influencers for advertising, this study interrogates influencers’ sponsored narratives of therapeutic experience. Through an illustrative case of Glowe , a leading Chinese counseling platform whose marketi...

AI-driven drug design for head and neck squamous cell carcinoma using GNN and structure-based simulations

Head and neck squamous cell carcinoma (HNSCC) remains a major global health burden with limited targeted therapeutic options. Here we present an integrated artificial intelligence (AI)-driven drug discovery framework combining graph neural networks (GAT, GCN, AttentiveFP and GIN)...

PSMD11 promotes hepatocellular carcinoma progression by reprogramming lipid metabolism via SREBP1/2 and PPAR-γ

Abstract Dysregulation of the ubiquitin-proteasome system (UPS) plays a pivotal role in tumor progression. PSMD11, a non-ATPase regulatory subunit of the 26S proteasome, has been implicated as an oncogenic factor in several cancer types; however, its precise biological function a...

Harnessing Diversity: Majority‐Group Acculturation Predicts Creativity and Flourishing Over Time

ABSTRACT Creativity and flourishing are core aims of higher education (HE) institutions and government initiatives globally. Large‐scale projects have linked creativity and flourishing with cultural diversity, yet their associations with majority‐group acculturation (i.e., how me...

A multicohort, biomarker-driven phase 2 trial of personalized total neoadjuvant therapy with targeted agents for high-risk rectal cancer (The TRAINER study)

This multicohort, single-center, phase II trial explored the efficacy and safety of a biomarker-driven total neoadjuvant therapy (TNT) regimen in high-risk locally advanced rectal cancer (LARC) patients. The regimen included induction chemotherapy (4 cycles of mFOLFOX6) with targ...

Establishing a single-cell RNA sequencing workflow using EUS-guided fine-needle aspiration for pancreatic ductal adenocarcinoma

Background and Objectives: No unified consensus exists regarding standardized protocols for single-cell RNA sequencing (scRNA-seq) analysis of samples obtained via EUS-guided fine-needle aspiration (EUS-FNA). This study aimed to evaluate the feasibility of applying scRNA-seq to E...

Evaluationof 18F-FPPA as a PositronEmission Tomography Radioligand for Imaging CSF1R in LPS-Induced RatModel of Neuroinflammation

Abstract Noninvasive detection of microglia is crucial for monitoring their spatiotemporal dynamics and facilitating early medical intervention during the prodromal stages of these neuroinflammatory diseases. Colony-stimulating factor 1 receptor (CSF1R) is a promising imaging bio...

A flat-band perspective on the boson peak in amorphous solids

The boson peak is a characteristic anomaly of amorphous solids broadly defined as a low-energy excess in the density of states and heat capacity compared to the textbook predictions of Debye theory. The origin of this anomaly has long been the subject of ongoing debate and remain...

Stroke survivors’ health priorities and targeted interventions in home-based post-discharge rehabilitation

<title>Abstract</title> Background This study aimed to describe health problems of the stroke survivors and the corresponding nursing interventions implemented during 12-week home-based post-discharge rehabilitation. Methods This was a descriptive secondary analysis within the co...

Relative Localization of a Floating Recovery Target in an Unmanned Surface Platform-Assisted UAV–ROV Search-and-Recovery System Under High Sea States

This study addresses target-to-ROV relative localization in an unmanned surface platform-assisted UAV–ROV search-and-recovery system. Because the submerged ROV is not assumed to be visible from the air, the UAV observes the floating target and a GNSS-equipped ROV-associated surfa...