New York University

Association between plain-water consumption and suicide attempts among U.S. adolescents: Evidence from the 2017–2021 Youth Risk Behavior Survey

Background Adolescent suicide attempts remain difficult to predict, in part because research has concentrated on a narrow set of risk factors. We examined whether self-reported plain-water consumption is associated with past-year suicide attempt among U.S. adolescents, whether th...

Early Revision Rates and Clinical Outcomes of Two Cementless Cruciate-Retaining Total Knee Arthroplasty Designs at Two-Year Follow-Up: A Propensity Score-Adjusted Comparative Analysis

Background and Objectives: Cementless total knee arthroplasty (TKA) has gained popularity but comparative outcome data across implant systems remain limited. This study compared survivorship and clinical outcomes of two cementless cruciate-retaining TKA implants from different ma...

Anticancer Drugs and Cancer-Associated Thrombosis

The rapid development of novel cancer therapies has considerably improved the care of cancer patients and cancer-related survival; however, these therapies are associated with a broad range of adverse events that have become a major burden in this population. Alongside other canc...

Consumption of Unpasteurized (Raw) Milk and Milk Products by Pregnant People and Children: Policy Statement

Sales of unpasteurized (raw) milk and milk products remain legal in at least 27 US states. Unpasteurized milk and milk products from cows, goats, and sheep continue to be a source of infections attributable to several virulent pathogens, including Listeria monocytogenes, Campylob...

Technology-Driven Evolution of Modern Toxicology: Role of Computational Toxicology

Toxicology is the study of the harmful effects of chemicals, substances, or environmental agents on living systems. Toxicity studies are essential for determining the health impact and risk-assessment of new drug molecules, cosmetics, healthcare and consumer products, and environ...

Effect of Advancements in Computer Technologies in Modern Healthcare Systems

Traditional digital healthcare primarily focuses on passive storage systems where the data is not used for making a clinical narrative or model new biological mechanics. To overcome these limitations, health informatics is adopting Large Language Models (LLMs) to automate clinica...

Topology-enforced synthesis of atomically precise silver nanoclusters in 3D DNA lattices

DNA nanotechnology leverages the molecular design resolution of the DNA double helix to fold and tile matter into designer architectures. Recent advances in bioinorganic chemistry have exploited DNA/Ag + affinity to carry out the templated reduction of silver nanoclusters. Here,...

Compiling WebAssembly Concolic Execution with Staging, Continuations, and Snapshots

Concolic execution is a variant of symbolic execution that runs a program simultaneously with concrete and symbolic inputs. It records the symbolic constraints encountered along a concrete execution path, then solves those constraints to generate inputs that explore new paths. Ex...

Consensus-based clinical and research recommendations for use of glucagon-like peptide-1 receptor agonists in the context of eating disorders: a modified Delphi study.

Glucagon-like peptide-1 receptor agonists (GLP-1RAs), initially developed for type 2 diabetes management and later expanded to obesity treatment, have shown preliminary efficacy in reducing binge eating episodes. However, the appetite-suppressing and weight-loss effects of GLP-1R...

Development and validation of VentPilot: an AI-based recommendation system for mechanical ventilation

BACKGROUND: Mechanical ventilation requires repeated adjustment to changing patient physiology, but consistent individualized management remains challenging. We developed VentPilot, an artificial intelligence-based system for recommending ventilator settings, and evaluated it in...

The lived experience of trans persons: a bottom-up review co-written by experts by experience and academics.

We present here the first bottom-up review of the lived experience of trans persons, co-written by experts by experience and academics. We sourced the medical and non-medical literature, focusing on first-person narratives, and critically extracted experiential themes, which were...

Evidence-based atlas of risk and protective factors for psychotic disorders: an umbrella review to inform personalized prognosis and prevention.

Identifying updated, evidence-based risk and protective factors for psychotic disorders is essential to advancing scientific and clinical knowledge of their etiology. Since the most recent umbrella review published in this journal, the evidence base has expanded substantially. Fo...

Sugar-rich foods exacerbate antibiotic-induced microbiome disruption

Diet shapes the composition of the gut microbiota1; however, the specific effects of distinct food groups on microbiome dynamics are unclear, particularly in circumstances of extreme perturbation. Here we evaluated the relationship between diet and intestinal microbiome dynamics...

DAIMON: Designing AI-Augmented Research Dashboards to Enable Novel Human-AI Collaborative Workflows in Longitudinal Sensing Studies

Researchers conduct longitudinal passive sensing studies in in-the-wild settings, often spanning months or years, to uncover naturalistic behavioral patterns. These studies are not “set-and-forget” deployments; they require continuous monitoring as technical failures and declinin...

Seamful Design Considerations for Human-in-the-Loop Digital Phenotyping of Mental Health

Digital Phenotyping of Mental Health (DPMH) through passive sensing is a promising approach for personal health informatics and digital wellbeing. Its appeal lies in unobtrusiveness, making it appear seamless. However, this very quality leads users to find it impersonal, untrustw...

Review Article: Cancer Surveillance for Early Detection of Liver Cancer in Patients with HBV Infection

BACKGROUND AND AIMS: Chronic hepatitis B virus (HBV) infection remains a major cause of hepatocellular carcinoma (HCC). Although antiviral therapy reduces cirrhosis and liver failure, HCC may still develop in patients with HBV, including in non-cirrhotic livers. This review aimed...

Hearts too small for body size after doxorubicin for childhood acute lymphoblastic leukemia: Grinch Syndrome

Cardiovascular disease is a major cause of morbidity and mortality in childhood cancer survivors. We assessed the very long-term cardiac structure and function of adult survivors of childhood leukemia treated with anthracycline-based therapy. One hundred fifteen patients with hig...

Environmental stochasticity reduces human planning effort

Abstract The world is stochastic, making planning difficult. Despite the ubiquity of stochasticity in real-world environments, it remains an open question how people effectively balance the cognitive costs of planning against its potential benefits when faced with stochasticity....

Hybrid RLHF-AIF: Uncertainty-Guided Routing of Human and AI Feedback for Cost-Efficient Safety Alignment of Large Language Models

Safety alignment of large language models faces a feedback dilemma: human judgment is reliable but costly to scale; automated judgment is cheap but less trustworthy. Existing methods commit to one source per run, so misjudged responses are never corrected. This paper proposes Hyb...

Latent Class Analysis of Prenatal Characteristics and Their Associations With Early Childhood Weight

ABSTRACT Objective Identify patterns of obesity‐related prenatal characteristics across ecological system levels and examine associations with child weight at 2 years old. Methods Secondary analyses were conducted using data from 533 low‐income Hispanic families enrolled in a chi...