New York University

Evolutionary and Functional Conservation of Topologically Associating Domain Boundaries in Rice Genomes

Traditional evolutionary analysis has relied primarily on one-dimensional (1D) sequencing data, but recent advances in three-dimensional (3D) genomics allow for deeper investigation of how genome architecture shapes evolutionary divergence. In this study, we analyze conserved and...

Effectiveness of High-Tech Assistive Devices for Upper Extremity Impairments on Performance of Activities of Daily Living: A Systematic Review

Date presented: April 25, 2026 Primary Author and Speaker: Selena Brujan, sob235@nyu.edu

Removing Tuition Dependency From Dental Education: Consensus Recommendations on Student Debt, Sustainability, and Pathway Reform

BACKGROUND: The current financing model for US dental education is increasingly misaligned with the goals of sustainability, equity, and workforce design. Tuition has risen substantially over time, educational debt among dental graduates remains high, and evidence suggests that p...

From Phase Ib/ II to Seamless Phase II / III : A Simulation‐Based Discussion of Design Strategies for Dose Optimization and Confirmatory Phase

The emergence of targeted therapies and immunotherapies has challenged the traditional "more is better" paradigm underlying maximum tolerated dose (MTD)-based trials, as dose escalation beyond receptor saturation often yields limited additional efficacy while substantially increa...

From Classification to Cross-Modal Understanding: Leveraging Vision- Language Models for Fine-Grained Renal Pathology

Fine-grained glomerular subtyping is essential for kidney biopsy interpretation, yet it presents a harder setting than the broad organ- or disease-level recognition tasks commonly used in vision-language model (VLM) evaluation. In this task, all categories arise within the same r...

Nonlinear Quantum Effects Drive Grotthuss Proton Conduction in Structured Electrolytes Based on Deep Eutectic Solvents

ABSTRACT Structured electrolytes based on deep eutectic solvents (DESs) face electrochemical limitations of vehicular diffusion due to high viscosities often leading to low conductivities. Here, we demonstrate that the inverse relationship between viscosity and conductivity in DE...

Designing Surprise Bags for Surplus Foods

Problem definition: Surplus-food marketplaces, such as Too Good To Go, enable retailers to monetize leftover inventory and reduce food waste by selling discounted “surprise bags.” Participating stores, however, face complex operational challenges. They must jointly set a reservat...

Theory-informed redesign of clinical reasoning education in the era of generative artificial intelligence

Abstract Clinical reasoning is a foundational competency that develops over the course of training and comprises two sub-components. Diagnostic reasoning classifies a patient’s condition and assigns a diagnostic label, whereas management reasoning weighs multiple defensible plans...

Shared patterns of human milk composition link mammary gland function to infant growth

The mammary gland produces nutrient-rich human milk (HM), yet how mammary functional state shapes HM composition and infant outcomes remains poorly understood. We used HM multi-omics - metabolomics, proteomics, micronutrients, macronutrients, and HM oligosaccharides - across 1,54...

A split attractor design for rapidly writing a navigational goal

Recurrent attractor networks are widely thought to form the basis of working memory1–3, but how they can be rapidly switched on and off is unclear4–7. Here we investigate stability and switching in a recurrent circuit of the fly navigation centre8. h∆K and PFG neurons are recurre...

A generalizable biopsychosocial risk score for stratifying disease vulnerability in healthy populations

Prospective risk stratification of future adverse health outcomes before clinical onset among ostensibly healthy individuals is an important goal of preventive and precision medicine, yet current tools remain largely disease-specific and do not provide an integrated measure of he...

Intra-individual variability of urinary non-persistent chemical concentrations during pregnancy in the ECHO Cohort

Studies of prenatal exposure to non-persistent chemicals often assume biomarker measurements from a single urine sample can represent exposure pregnancy. The validity of this assumption depends on biomarker concentration variability across gestation, which is not well-characteriz...

Sensory receptor expansion and neural accommodation in butterfly color vision

The evolution of complex brains required the incorporation of newly evolved neurons into existing circuits, yet the genetic and developmental mechanisms enabling their integration remain poorly understood. Butterflies expanded their color vision by adding a second R7 photorecepto...

Temporal, Geographic, and Polysubstance Patterns in Orphine Analogue Detections

This cross-sectional study examines the temporal, geographic, and polysubstance patterns in orphine analogue detections.

Building blocks of localized storm tracks: revisiting asymmetries between the NH and SH in storm track strength

An intermediate-complexity moist general circulation model is used to investigate the forcing of localized storm tracks by land–sea contrast, horizontal gradients in ocean heat uptake, planetary albedo, and topography. The additivity of the response to these building blocks is in...

Prognostic implications of complications during VA-ECMO for cardiogenic shock

PURPOSE: Veno-arterial extracorporeal oxygenation (VA-ECMO) provides comprehensive cardiopulmonary support in patients with cardiogenic shock (CS), but may result in complications. While complications rates are known, their impact on risk of death remains largely unknown. METHODS...

Highly multiplexed mammalian metabolic engineering with a shotgun approach

Mammalian metabolic engineering advances basic biology, bioproduction and cell therapy. However, as pathway complexity increases, so does the size of the combinatorial design space and required DNA constructs, rendering unbiased screens intractable. Here, we developed shotgun gen...

Association between plain-water consumption and suicide attempts among U.S. adolescents: Evidence from the 2017–2021 Youth Risk Behavior Survey

Background Adolescent suicide attempts remain difficult to predict, in part because research has concentrated on a narrow set of risk factors. We examined whether self-reported plain-water consumption is associated with past-year suicide attempt among U.S. adolescents, whether th...

Random analog prediction provides a benchmark for seasonal Arctic sea ice extent forecasting

Abstract We develop a random analog predictor (RAP) algorithm for the forecasting of Arctic sea ice extent (SIE) on seasonal timescales. This is a stochastic variant for scalar time series of the method of the analogues that only uses the historical SIE record to produce ensemble...

Evaluation of Pre‐Operative Cartilage and Meniscus Ultrashort Echo Time T2 * as Biomarkers of Long‐Term Clinical Outcomes Following Anterior Cruciate Ligament Reconstruction

ABSTRACT Background Ultrashort echo time T2* (UTE‐T2*) mapping is sensitive to the composition of deep cartilage and menisci. UTE‐T2* elevations are common after anterior cruciate ligament (ACL) injuries, but their long‐term prognostic importance is unknown. Hypothesis Higher pre...