New York University

Separable downmodulation of meiotic axis protein deposition and DNA break induction at chromosome ends

Abstract In many organisms, meiotic crossover recombination is suppressed near the extreme ends of chromosomes. Here we show that multiple, often chromosome-specific, suppressive mechanisms with differing ranges contribute to the consistently low enrichment of recombination-promo...

Hidden or undetected? Quantifying the boundary between structural bias and statistical noise in peer review

Purpose Peer review shapes not only the evaluation of scientific claims but also whose work gains visibility and influence. A growing body of evidence shows that review outcomes can mirror structural inequities tied to authors' identities, language backgrounds, institutional posi...

An unexpected twist: Isolated fallopian tube torsion in a term nulliparous patient

Introduction: Isolated fallopian tube torsion (IFTT) is the rotation of a fallopian tube without involvement of the ovary or adjacent vascular structures. It is a profoundly rare gynecologic emergency. Diagnosis is challenging because presenting symptoms and imaging findings are...

The basins of attraction of soft-sphere packings are not fractal

The energy landscape picture is a central tool to study many-body systems. In particular, the energy landscapes of glass-forming liquids, jammed packings, constraint satisfaction problems, or neural networks contain a plethora of minima corresponding to competing states. Due to t...

Clinician Use of an Artificial Intelligence–Enabled Clinical Information Platform

Importance Despite growing interest in the use of artificial intelligence (AI) in medicine, empirical evidence on how clinicians use these tools is limited. Objective To characterize clinician use of an AI-enabled clinical information platform, the distribution of use across the...

Foveated metamers of the early visual system

Abstract The ability of humans to discriminate and identify spatial patterns varies across the visual field, and is generally worse in the periphery than in the fovea. This decline in performance is revealed in many kinds of tasks, from detection to recognition. A parsimonious hy...

Evaluating Smart Home Device Users’ Responses to their (Un)Confirmed Privacy Expectations

Users of smart home devices are often unaware of how their devices handle personal data. We examine how revealing these data practices influences users’ trust, satisfaction, and coping behaviors, including decisions to block device communications. Using Expectation-Confirmation T...

Who votes when? Midterm and presidential voters differ primarily by age

Voters in American congressional midterm elections are widely viewed as demographically less representative than those in presidential elections – older, whiter, wealthier, and more educated. Using Current Population Survey data from 1994 through 2024 as well as voter-file data,...

Ice-ray pentagonal packing of pseudo-fivefold helices

While fivefold point symmetry is common in nature, fivefold spatial symmetry is seldom observed. Regular pentagons cannot tile a plane without leaving voids, and even the densest “ice-ray” packing is exceptionally rare. Fivefold helices are equally elusive. We report a small mole...

Sexual Orientation and Gender Identity Data and HIV Preexposure Prophylaxis Disparity Detection

Importance US federal reporting changes in 2025 removed sexual orientation and gender identity (SOGI) measures from health-center reporting, raising concerns about equity surveillance. Objective To quantify how incomplete or absent SOGI data are associated with detection of dispa...

Lighting and circadian cues shape locomotor strategies for balance and navigation in larval zebrafish

Most fish are inherently unstable and must swim to stabilize posture. How diurnal fish reduce activity at night while maintaining postural control remains unclear. We defined distinct locomotor strategies that larval zebrafish (Danio rerio) use to control posture and navigate the...

Sex work or male-with-male sexual activity and the risks of HIV and hepatitis C acquisition among people who inject drugs: a global systematic review and meta-analysis

Background People who inject drugs (PWID) may engage in sexual behaviours that increase their HIV and hepatitis C virus (HCV) risk, including sex work and male-with-male sexual activity. We undertook a global systematic review to assess whether PWID who engage in these behaviours...

Joint Optimization of Retrieval-Augmented KV Caching and Adaptive Speculative Decoding for Autoregressive Generation

Abstract Retrieval-assisted key–value (KV) reuse and speculative decoding remove different costs, but their naive composition can leave draft and verification overhead after prefill is shortened. RAKV-ASD combines exact causal prefix validation with a measured controller that sel...

Scalable and Personalized Oral Assessments Using Voice AI

When written work no longer shows who did the thinking, voice AI can bring back the oral exam at scale.

AI-generated language remains systematically distinguishable from human communication

Large language models (LLMs) are increasingly used in the social sciences to simulate human behavior and communication, yet validation methods for these applications remain limited. Existing evaluations often rely on human judgments of plausibility, a coarse, difficult-to-scale,...

Interim Update on Reactive Infectious Mucocutaneous Eruption ( RIME )

ABSTRACT Reactive infectious mucocutaneous eruption (RIME), a term describing blistering skin and mucosal lesions, is a term coined by a group of Pediatric Dermatology Research Alliance (PeDRA) researchers and first published in 2021. Since that time, the literature has grown wit...

Gaps in diabetes care among people living with HIV and hypertension in Botswana: A cross‐sectional analysis of the InterCARE study

Abstract Objectives Data on diabetes screening and monitoring, within HIV care programmes in sub‐Saharan Africa, remain limited. This study describes the quality of diabetes screening and management among people living with HIV with comorbid hypertension receiving care at facilit...

Reductionism Redux: How Some Forms of Reduction Preserve Psychology’s Person-Level Subject Matter

Psychology’s historical alignment with the ontologies and epistemologies of natural science gave rise to the lamentations of theoretical psychologists who find therein a reductive treatment of what they regard as psychology’s legitimate subject matter—mental life, lived experienc...

Lactation Failure in Postpartum Women Receiving a Dopamine Partial Agonist During Pregnancy

Background Third-generation antipsychotics like aripiprazole can suppress prolactin secretion via the tuberoinfundibular pathway, leading to postpartum lactation failure. This case series assesses the clinical management of this under-recognized postpartum complication in women w...

Evolutionary and Functional Conservation of Topologically Associating Domain Boundaries in Rice Genomes

Traditional evolutionary analysis has relied primarily on one-dimensional (1D) sequencing data, but recent advances in three-dimensional (3D) genomics allow for deeper investigation of how genome architecture shapes evolutionary divergence. In this study, we analyze conserved and...