Friedrich-Alexander-Universität Erlangen-Nürnberg

Characteristic central nervous system fingerprints and related molecular signatures in difficult-to-treat rheumatoid arthritis

Abstract Background Despite guideline-recommended treatment, approximately 30% of rheumatoid arthritis (RA) patients remain symptomatic and are classified as difficult-to-treat (D2T), representing an unmet clinical need. D2T RA is a heterogeneous state potentially involving diffe...

Early life sugar rationing and ageing related diseases, biological ageing and mortality

Early-life nutrition may influence lifelong ageing, yet human evidence is scarce. Using Britain’s postwar sugar rationing as a natural experiment, we examine its long-term effects in 64,809 United Kingdom Biobank participants. Exposure to sugar rationing during the first 1,000 da...

The magnetic removal of PFAS from water − from molecules to microplastics

Per- and polyfluoroalkyl substances (PFAS), known as “ forever chemicals ”, pose a persistent environmental threat due to their chemical stability, bioaccumulation and widespread presence in water sources. Traditional treatment methods are often limited to remove PFAS, especially...