Friedrich-Alexander-Universität Erlangen-Nürnberg

Knowledge and Risk Perception Regarding Skin Cancer in Immunosuppressed Patients: A Systematic Review and Meta-Analysis

Immunosuppressed patients have a substantially increased risk for developing skin cancer. Therefore, it is mandatory that such patients are adequately informed and aware of skin cancer and their increased risk to modify their behavior. Numerous studies have evaluated the topic, b...

Assessing climate change-related health hazards: An interactive tool for regional risk analysis in Germany

An interactive online health risk assessment has been created to visualize the health risks associated with climate change at the district level (NUTS3) across Germany. The tool provides a comprehensive assessment by depicting both the current risk patterns and projected conditio...

Virtual worlds and mental health: A scoping review

<title>Abstract</title> The constant increase in the use of virtual worlds in recent decades has raised concerns about their potential effects on users’ mental health. However, the great heterogeneity of the scientific literature on this topic makes it difficult to identify exist...

Vibrational power spectra as a tool to benchmark universal machine-learning interatomic potentials for molecular systems: the OMOL-1k-MD data set

Abstract We present OMOL-1k-MD, a new dataset for the benchmark and training of universal machine-learning interatomic potentials (uMLIPs). It contains three independent ab initio molecular dynamics (AIMD) trajectories of 10 ps each for 1000 arbitrarily chosen neutral closed shel...

Raw data to "Unconventional entanglement scaling and quantum criticality in the long-range spin-one Heisenberg chain with single-ion anisotropy"

This directory contains the data used to generate the numerical results in the work "Unconventional entanglement scaling and quantum criticality in the long-range spin-one Heisenberg chain with single-ion anisotropy [1]". [1]: P. Adelhardt, S. R. Muleady, K. P. Schmidt, and A. V....

First-line immune checkpoint inhibitors versus chemotherapy in delaying quality of life deterioration in advanced NSCLC: a systematic review and meta-analysis

Backgroud: Immune checkpoint inhibitors (ICIs) have transformed first-line treatment for advanced non–small-cell lung cancer (aNSCLC). While overall survival(OS) remains the primary endpoint, health-related quality of life (HRQoL) is a key patient-centered outcome. Time to deteri...

Adapted foundation models for breast MRI triaging in contrast-enhanced and non-contrast-enhanced protocols

Abstract Objectives To evaluate a DINOv2-based medical slice transformer (MST) for triaging abbreviated breast MRI by ruling out examinations with suspicious findings that are immediately actionable (Breast Imaging Reporting and Data System [BI-RADS] ≥ 4) across contrast-enhanced...

Long-Lived Interfacial Charge Separation in PyrenylimidazolylPhthalocyanine@Transition Metal Dichalchogenide Heterostructures

Abstract Pyrenylimidazolyl-functionalized free-base phthalocyanines (H2Pc) and their zinc complexes (ZnPc) constitute multifunctional building blocks for realizing heterostructures with liquid phase exfoliated transition-metal dichalcogenides (LPE-TMDs). Here, we report the synth...

GeoHash3D: Robust and Efficient 6-DoF Pose Estimation from 3D Marker Sets

Accurately measuring the six degrees of freedom (6-DoF) pose of a sample is a critical prerequisite for applications in robotic sample handling, optical metrology, and industrial quality control. Our pose estimation problem requires matching a small, partial observation of 4–20 d...

Spot melting in electron beam powder bed fusion: influence of the melt pool shape on microstructure and texture

Abstract Reliable microstructure control remains a major challenge in electron beam powder bed fusion, particularly for Ni-based superalloys such as IN718, where large columnar grains with a strong $$\langle 100\rangle $$ texture cause highly anisotropic behavior, often limiting...

Effects of hyperbaric oxygen therapy on human musculoskeletal pathologies in clinical studies: a systematic review

Abstract Background Hyperbaric oxygen therapy (HBOT) has gained increasing interest in regenerative medicine for its capacity to enhance tissue oxygenation, reduce inflammation, and accelerate healing. While its use in musculoskeletal medicine is expanding, particularly among ath...

Effect of apremilast on entheseal bone damage in psoriasis patients at risk of developing psoriatic arthritis - data from the prospective, interventional EPOS study

BACKGROUND/PURPOSE: A subset of psoriasis (PsO) patients exhibits subclinical entheseal inflammation and bone remodeling placing them at higher risk of developing psoriatic arthritis (PsA). Whether early pharmacological interventions during this phase can modulate these inflammat...

A novel synergistic phycobiliprotein combination against HIV-1 shows potent antiviral activity

Human immunodeficiency virus type 1 (HIV-1) remains a major global public health challenge due to lifelong persistence, latency, and the emergence of drug resistance. Natural bioactive compounds are increasingly being explored as alternative or adjunct antiviral strategies. In th...

Orthogonal Functionalization of Oxide/Metal Nanostructures: Carboxylate and Thiol Self-Assembled Monolayers on CoO/Au(111)

The orthogonal self-assembly of anchored molecular monolayers on chemically heterogeneous substrates offers a route for bottom-up chemical nanopatterning and area-selective deposition. Herein, we investigated the selective growth of self-assembled monolayers (SAMs) of n-decanethi...

Diagnostic Accuracy of APTw and NOEw MRI Metrics for IDH Mutation and 1p/19q Codeletion Prediction in Gliomas

ABSTRACT Isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion are key molecular markers for glioma classification. Amide proton transfer weighted (APTw) and nuclear Overhauser effect–weighted (NOEw) markers showed promise for glioma characterization, by probing protein‐r...

Unveiling Float Glass Staining Induced by an Acid‐Cleaning Product

ABSTRACT Staining of glass facades is a recurring and significant problem worldwide. This study investigates the causes of staining observed on six laminated float glass samples from four manufacturers (α, β, γ, and δ). Samples from β, γ, and δ were new, whereas those from α (α 1...

Color Symmetry Breaking in a Nonlinear Optical Microresonator

ABSTRACT Spontaneous symmetry breaking leads to diverse phenomena across the natural sciences, from the Higgs mechanism in particle physics to superconductors and collective animal behavior. In photonic systems, the symmetry of light states can be broken when two optical fields i...

eRASSU J043115.8-711730 The first pulsating symbiotic super-soft X-ray source in the Magellanic Bridge

Abstract The Magellanic Bridge stellar population is a relic of the tidal interaction between the Large and Small Magellanic Clouds. A comprehensive view of the evolution of the Bridge stellar population requires probing the compact remnants of stellar evolution, otherwise hidden...

Reconceptualizing the ethics of diagnosis: a Foucauldian framework

Abstract Background Traditional approaches in medical ethics have primarily focused on the consequences of diagnoses, emphasizing their impact on patients’ lives, treatment options, and social perception. While this perspective remains indispensable, it is limited in its consider...

Advances and challenges in powder flowability and fluidization quality

Flowability and fluidization quality of bulk solids are closely interlinked and decisive for the processing behavior and homogeneity of product quality in many applications, ranging from fine chemicals to energy generation. In this perspective, we summarize recent advances in the...