Chinese University of Hong Kong

Epidemiology of ocular surface squamous neoplasia and squamous papillomas in Hong Kong Chinese: A 10-year review

Background/Aims We aim to report the risk factors, clinicopathological characteristics, treatment modalities, and outcomes of ocular surface squamous neoplasia (OSSN) and squamous papilloma (SQP) in a Chinese population. Methods A retrospective cohort study was performed on subje...

A multimodal discourse analysis of teacher discourse practices in early childhood STEM activities

Abstract This study investigates how a kindergarten teacher in Mainland China used multimodal discourse to support children’s problem-solving during STEM activities. A qualitative case study was conducted, combining systemic functional linguistics and grounded theory to analyze i...

The Relationship Between Wu 無 and Dao 道 in the Daodejing 道德經: Beyond Nothingness in a Decolonial Direction

Abstract This article examines the relationship between wu 無 and dao 道 in the Daodejing 道德經 to explore its resonances with decolonial thought––understood here first as the dismantling of colonial impositions within the philosophical imaginary, and subsequently as a resource...

p38β-mediated BiP phosphorylation drives stemness and chemoresistance by suppressing UPR activation in hepatocellular carcinoma

Abstract Tumor-initiating cells (TICs) promote tumor initiation and therapy resistance, yet the kinase regulators that sustain TICs remain incompletely defined. Here, we identify the stress kinase p38β (MAPK11) supports TIC maintenance and drug resistance in hepatocellular carcin...

"Just Part of Aging?" Sleep-Problem Normalization, Sleep-Related Worry, Help-Seeking, and Emotional Distress Among Chinese Older Adults

Many older adults experience poor sleep but do not always view it as a problem requiring help. This thesis examines sleep-problem normalization (SPN), defined as the belief that poor sleep is an expected or less serious part of aging. Although sleep-related cognitions and views o...

Capacitance-Based Characterization of Air-Void Distribution in Asphalt Mixtures Using a Saturated Reference Field

Air-void distribution is an important internal characteristic of asphalt mixtures, as it affects compaction quality, moisture susceptibility, permeability, and long-term pavement durability. Conventional air-void testing methods generally provide only an average volumetric parame...

Mitigating Stress‐Induced Nonphotoactive Phase Transition Through Sodium Sulfonate Engineering for Stable and Efficient Perovskite Solar Cells

ABSTRACT Formamidinium lead triiodide (FAPbI 3 ) perovskite solar cells (PSCs) have attracted significant attention due to their outstanding optoelectronic properties. However, their long‐term stability remains limited by lattice strain‐induced transition from the photoactive α‐p...

Predicting infection risk in rheumatoid arthritis patients receiving biological or targeted synthetic disease-modifying anti-rheumatic drugs: an application of machine learning and healthcare big data

Patients with rheumatoid arthritis (RA) initiating biologic or targeted synthetic disease-modifying antirheumatic drugs (b/ts DMARDs) face elevated risk of serious infections, necessitating tools for individualized risk stratification. Primary objective was to develop and validat...

Retirement and Personality Trait Development: A Continuous Time Meta-Analysis

The project thus pursues two interrelated goals: substantively, to evaluate whether retirement constitutes a robust and replicable factor of personality trait change.

Cumulative non-high-density lipoprotein cholesterol exposure and residual cardiovascular mortality risk in patients with peripheral artery disease

Abstract Background Individuals with peripheral artery disease (PAD) face substantial residual cardiovascular risk despite lipid-lowering therapy. Non-high-density lipoprotein cholesterol (non-HDL-C) has been recognized as a more comprehensive marker of cardiovascular risk than l...

Phage as a prospective arsenal against superbugs

The escalating crisis of antimicrobial resistance (AMR) necessitates the urgent development of alternatives to traditional antibiotics. Bacteriophage (phage) therapy, which utilizes viruses that specifically infect and lyse bacteria, has re-emerged as a promising therapeutic stra...

From fear to fun: leveraging AI-powered videos in nursing education for disaster preparedness

Abstract Background Disasters are increasingly prevalent nowadays, whether it is mass casualty incidents, pandemics, or the growing impact of climate change and conflicts. Nursing students should be prepared to be competent nurses, so that they can react safely and efficiently in...

Small molecule modified peptides are used to regulate their liquid-liquid phase separation characteristics

Liquid-liquid phase separation (LLPS) is a phenomenon in which a uniform mixture spontaneously divides into two liquid phases with differing component concentrations. It is prevalent in soft matter, is observed in systems involving polymers, organic molecules, and proteins, and i...

Neurocognitive Functions and Their Associations With Autistic Symptoms, Emotion, and Behavior in High-Functioning Children and Adolescents With Autism Spectrum Disorder

Objective Studies have revealed the prognostic significance of intelligence in children with autism spectrum disorder (ASD), but the correlations of non-social cognitive functions and clinical characteristics of high-functioning children and adolescents with ASD remain unclear. T...

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...

Shielding against interpersonal threat in later life: The regulatory function of nostalgia among older adults.

= 189, age 21-78 years), older adults reported greater nostalgic engagement in response to social exclusion induced by the Cyberball game than younger adults. Furthermore, after experiencing nostalgia, compared to younger adults, older adults reported increased social engagement...

Gay Men in Midlife: Moral Time and Temporal Expectations in Hong Kong, Shenzhen and Macau

This qualitative research project examines how time operates as a moral classification system in shaping the self-understandings of gay men aged 35–55 in Hong Kong, Shenzhen, and Macau. Rather than treating midlife as a biological stage, the study conceptualizes it as a culturall...

Tibial cortex transverse transport accelerates diabetic wound healing via systemic mobilization of non-classical monocytes

Aims: To clarify the immunomodulatory mechanisms by which tibial cortex transverse transport (TTT) accelerates wound healing in a type 2 diabetic rat model, with particular focus on the dynamics of subsets of monocytes and macrophages. Methods: A total of 186 male Sprague-Dawley...

Spectral configurations and interferences in outdoor artificial light at night (ALAN) exposure measurements and sleep quality modeling

Outdoor artificial light at night (ALAN) may impact human health through disturbing human circadian rhythms. Laboratory experiments have shown that spectral differences in ALAN may lead to disparities in disturbing human circadian rhythms, but such spectral differences are overlo...

Counterfactual load forecasting with LLM-structured events and representation learning

News-reported social, environmental, and grid events can substantially reshape electricity demand, yet quantifying how such events perturb forecasted load trajectories remains largely unaddressed. Existing news-augmented forecasting studies use news as auxiliary features to reduc...