Chinese University of Hong Kong

Measuring the longitudinal HIV pre-exposure prophylaxis and condom usage pattern in men who have sex with men: short-call diary versus monthly survey

Abstract Background While a diary is ideal for recording daily sexual activity and drug taking, summarised survey is commonly used in real-world settings. This study aims to compare the robustness of short-recall diary with monthly survey on PrEP and condom use in men who have se...

Multi-fidelity methods for kinetic models of epidemic dynamics with uncertain contact structure

In this work, we develop a multi-fidelity strategy for kinetic models in epidemiology with uncertain contact dynamics. Assessing and controlling the population-level effects of contact dynamics requires the development of models for understanding observable effects of heterogeneo...

Multi-channel Non-radiative Dynamics to Reveal Δ E ST as the Key Efficiency Descriptor for Deep-Blue Pt(II) Phosphors

Abstract Tetradentate platinum(II) complexes are promising candidates for phosphorescent organic light-emitting diodes (OLEDs), combining deep-blue emission, high color purity, and potential for near-unity photoluminescence quantum yields (PLQYs). However, despite their rigid str...

Spelling error patterns in the co-occurrence of reading and spelling difficulties among Chinese children

Abstract Reading difficulties (RD) and spelling difficulties (SD) frequently co-occur in children and are associated with persistent spelling problems. However, little is known about spelling error patterns in Chinese among children with RD, SD, or their co-occurrence (RDSD). The...

Schizophrenia research in 2026: report from the annual meeting of the Schizophrenia International Research Society

Abstract SIRS 2026, held under the theme “Schizophrenia Research in the Era of Artificial Intelligence,” brought together researchers, clinicians, and persons with lived experience to take stock of a field whose tools for measuring, predicting, and intervening in psychosis have e...

PPARγ/P21 Signaling Mediates Butyrate-Driven Protection against Aging-Related Endothelial Dysfunction: A Novel Effect of Soybean Polysaccharide via the Gut-Vascular Axis

Abstract Aging-induced endothelial dysfunction is a core driver of age-related cardiovascular diseases (CVDs). In 20-month-old naturally aged mice, 12-week soybean polysaccharide (SP) supplementation restored endothelium-dependent relaxation, reduced aortic reactive oxygen specie...

Multiscale Methods for Wave Propagation in Materials with Sign-Changing Coefficients

Abstract. From a mathematical perspective, the extraordinary properties of metamaterials are often reflected in the coefficients of the governing partial differential equations. These coefficients may fall outside the assumptions of classical theory, particularly when the effecti...

Proximity‐Induced Protein Deglycosylation by Endogenous O‐GlcNAcase

ABSTRACT O‐GlcNAcylation is an important post‐translational modification that regulates numerous cellular processes, yet tools enabling selective removal of O‐GlcNAc from individual proteins via endogenous O‐GlcNAcase (OGA) in living cells remain limited. Here, we report De‐O‐Glc...

Digital Payment Adoption and Financial Vulnerability: Global Evidence From Multilevel Models

ABSTRACT Although digital financial services are emerging, whether adopting digital payment influences consumer vulnerability remains understudied and debated. This study aims to examine mechanisms linking digital payment adoption, financial fragility, financial worry, and nation...

Localized Patterns in the Gierer Meinhardt Model on a Cycle Graph

Abstract. In this study, we provide a detailed analysis of the spike solutions and their stability for the Gierer–Meinhardt model on discrete lattices. We explore several phenomena that have no analogs in the continuum limit. For example in the discrete case, the system retains s...

DNA-Encoded Binding Affinity Shapes Robust CTCF Occupancy Across Cellular Contexts

CCCTC-binding factor (CTCF) is an architectural protein that organizes 3D genome architecture by binding to tens of thousands of genomic loci in a typical human cell type. Although DNA-binding affinity contributes to CTCF occupancy in vivo, the principles distinguishing robust fr...

Programmable Temporal Dynamics in a Laser Neuron for High‐Speed Photonic Reservoir Computing

ABSTRACT Memory and nonlinearity play crucial roles in reservoir computing (RC) performance, with different tasks requiring different levels of these properties. However, in most physical RC systems, memory and nonlinearity are fixed or can only be changed through hardware redesi...

Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026

Abstract Background Gastric cancer (GC) remains a major global health burden, and early detection is essential for improving patient outcomes. Although GC screening has been widely implemented in East Asian countries with a high disease burden, the optimal screening strategy for...

A cross-sectional study of eating attitudes in Hong Kong athletes

Abstract Numerous studies have explored disordered eating (DE) in athletes, yet their findings frequently conflict. This research focused on examining the prevalence of DE among HK Chinese athletes. A sample of 100 athletes participated in the study, which employed a cross-sectio...

Transforming the Landscape of Drug Innovation in AI Era: AlphaFold 3 and Beyond

ABSTRACT The traditional drug discovery and development (DDD) pipeline has long been characterized by inefficiency and high costs. The rapid evolution of artificial intelligence (AI), especially AI‐based toolkits for protein structure and interaction prediction, exemplified by Al...

Magnetically Induced Functional Fe 3 O 4 /Iron Foam Catalysts for Enhanced CO 2 ‐Assisted Ethane Dehydrogenation

ABSTRACT CO 2 ‐assisted ethane dehydrogenation (CO 2 ‐EDH) combines olefin production with CO 2 conversion, yet suffers from high temperatures and catalyst instability in thermal catalysis. This work establishes an alternating current magnetic field (ACMF)‐mediated catalytic syst...

Overcoming the Dark Current–Spectral Range Trade‐Off in Room‐Temperature Two‐Dimensional Photodetectors via Photothermal‐Assisted Tunneling

ABSTRACT The intrinsic trade‐off between low dark current and broadband detection fundamentally limits the performance improvement of 2D photodetectors. Here, we report a MoTe 2 /h‐BN/graphene tunneling heterostructure photodetector that synergistically integrates the high insula...

Exploratory Study on the Potential Moderating Effects of Protective and Risk Factors on the Negative Impact of Parental Stress on Family Quality of Life in Parents of Children With Autism (CLWA)

ABSTRACT Chinese caregivers of autistic children report heightened parental stress, which in turn can negatively influence their family quality of life (FQoL). To better support the quality of life of Chinese caregivers of autistic children, the present study investigated the rel...

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer‐related mortality. Integrative multi‐omics and machine‐learning analyses across independent cohorts identified CYYR1 as a frequently downregulated transmembrane protein in LUAD, with low expression associated w...

Electrochemical Control of Scholl Reaction: Arenium Cation Versus Radical Cation Pathways

ABSTRACT The Scholl reaction is a cornerstone method for constructing polycyclic aromatic hydrocarbons, yet its mechanism remains highly debated because arenium and radical cation intermediates are difficult to characterize. Herein, we demonstrate that electrochemical oxidation p...