Centre National de la Recherche Scientifique

Environmental and demographic determinants of Aedes albopictus seasonal activity in southern France: A modeling study

The presence and the activity of Aedes albopictus are a growing concern for nuisance and public health in Europe. Despite an increasing number of entomological and modelling studies, our incomplete understanding of mosquito population response to weather drivers in natural condit...

p190A / ARHGAP35 and p190B / ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Endometrial cancer is one of the main gynecological malignancies worldwide. Several studies highlight ARHGAP35 as a significantly mutated gene in these tumors. It encodes for p190RhoGAP-A (p190A), which is a major regulator of the small GTPase family of proteins. ARHGAP5 is a par...

A Reproducible MRI‐Based Pipeline for Longitudinal Tracking of Laser‐Assisted Bioprinted Cells in Three‐Dimensional Constructs

ABSTRACT Laser‐assisted bioprinting (LAB) enables precise spatial patterning of living cells within three‐dimensional constructs; however, the lack of non‐destructive, standardised methods for longitudinal evaluation remains a major limitation to construct optimisation and transl...

Archaeozoology and Biomolecular Analysis in Archaic Phoenician Gadir—The Site of Sagasta–Tinte (9th–8th Centuries BC)

Faunal remains constitute one of the main sources of evidence for reconstructing foodways and economic practices in Phoenician societies. Archaeological research conducted over recent decades in the Iberian Peninsula has highlighted their importance for understanding food product...

Perinatal exposure to nano-polystyrene: deleterious imprinting on inflammatory bowel diseases

The extent of production and use of plastics leads to release of nanoplastics (NPL) into the environment, where they undergo weathering that could alter their toxicological properties. NPL enter the human food chain via contaminated food, and food packaging, and within the body t...

Aliphatic Diazirines Synthesis Mediated by Mild N -Chlorosuccinimide Oxidation

Abstract Diazirines have been known for decades as effective photoreactive moieties, with valuable applications in chemoproteomics. In recent years, they have received increasing interest in synthetic chemistry. Until recently, their access required a multistep process, which may...

Two‐Block Paths in Oriented Graphs of Large Semidegree

ABSTRACT We study the existence of oriented paths with two blocks in oriented graphs under semidegree conditions. A block of an oriented path is a maximal directed subpath. Given positive integers and with , we establish a semidegree function that guarantees the containment of ev...

Weak-Strong Uniqueness for the Landau Equation by a Relative Entropy Method

Abstract. We derive a weak-strong uniqueness and stability principle for the Landau equation in the soft potentials case (including Coulomb interactions). The distance between two solutions is measured by their relative entropy, which to our knowledge was never used before in sta...

Real-space spin-orbit interaction from quarter-wave plate nonuniformity

Abstract Spin–orbit interactions couple light polarization to its transverse structure. Although widely studied at interfaces, in tilted anisotropic plates, and under tight focusing, their role in paraxial confocal systems remains unclear. We show that a commercial quarter-wave p...

Advancing conflict research and response through satellite-derived data

Abstract With armed conflicts at a historic high and attacks on civilians rising 1 , understanding the evolving nature of conflict is a critical research priority. The current paradigm in conflict research relies heavily on text-based data, using fatalities as the primary—and oft...

Mean-Field Limit for Stochastic Control Problems under State Constraint

Abstract. We study the convergence problem of mean-field control theory in the presence of state constraints and nondegenerate idiosyncratic noise. Our main result is the convergence of the value functions associated to stochastic control problems for many interacting particles s...

The added value of Med-CORDEX coupled high-resolution regional climate models in representing sea surface temperature and marine heatwaves in the Mediterranean Sea

Marine heatwaves (MHWs) pose significant threats to Mediterranean marine ecosystems and coastal economies, with frequency and severity projected to increase under future climate change. While Med-CORDEX fully-coupled Regional Climate System Models (RCSMs) offer enhanced resolutio...

Immunomodulatory Amacstatins facilitate feeding and Rickettsia parkeri transmission by Amblyomma maculatum ticks

Ticks rely on salivary immunomodulators to sustain prolonged blood feeding and transmit pathogens, yet the protein effectors that mediate these processes remain incompletely defined. Here, we characterize three divergent cysteine protease inhibitors—Amacstatins—from the Gulf Coas...

Macroevolutionary Rates of Species Interactions: Approximate Bayesian Inference from Cophylogenies

Abstract Understanding the macroevolutionary dynamics of species interactions such as parasitisms, commensalisms, and mutualisms is an important goal in evolutionary ecology. To this end, statistical inference from time-calibrated cophylogenies holds promising potential. However,...

Characterization of the GARIS-III Separator via the 40 Ar + 208 Pb Fusion Evaporation Reaction

This work reports on the measurements performed during the commissioning of the GARIS-III separator in RIKEN with the study of the 40 Ar + 208 Pb → 248 Fm * reaction. The excitation functions of the 2n, 3n, and 4n exit channels were measured with maximum cross sections of 27.5 ±...

Ancient DNA preservation in the Caribbean

Abstract Ancient DNA (aDNA) analysis has transformed how we study human migration, species dispersals and environmental change, but poor preservation remains a major challenge. This is especially true in tropical settings, where hot and humid conditions accelerate DNA decay. Beca...

Super‐Electron‐Donor Polymers: From Monomer Design to Redox Functionality

ABSTRACT The design flexibility of organic materials has enabled numerous applications for energy storage systems. However, few examples of low‐potential p‐type materials for the negative electrode are known in the field of organic batteries, particularly relevant for anion‐rocki...

On destructive memories and the role of language in living with one’s past

Abstract In the context of memory, the present paper investigates the consequences of undergoing a change concerning one’s ethical outlook. First, we motivate the idea that we can become alienated from our own memories by revisiting Bernard Williams’ idea of Relativism of distanc...

Stability Analysis of Nonseparable Mean-Field Games for Pedestrian Flow in Large Corridors

Abstract. We investigate the existence and stability of small perturbations of constant states of the generalized Hughes (GH) model for pedestrian flow in an infinitely large corridor. We show that constant flows are stable under a condition on the density. Our findings indicate...

Plasma membrane order maps functional diversity in immune cells

Abstract Cell membranes undergo biophysical remodeling as an adaptation to the surroundings and to perform specific biological functions. However, the extent and relevance of such changes in human immune cells remain unknown, largely because of the lack of single-cell and multidi...