Central South University

Mitochondrial Remodeling, Cytoskeletal Dynamics, and Translational Control During Drosophila Spermatid Elongation: An Integrative Review

Spermatogenesis in Drosophila melanogaster is a classical model for studying cell polarity establishment, organelle remodeling, and extreme cellular morphogenesis. Spermatid elongation involves a series of highly coordinated dynamic events, including nuclear polarization, axonema...

Groundwater environmental assessment of cemented backfill prepared from decyanidated tailings: evidence from 30-day static immersion tests

Decyanidated tailings are increasingly used as aggregates for underground cemented backfill, but their potential effects on groundwater quality remain uncertain. In this study, cemented backfill samples prepared from decyanidated tailings from Suichang Gold Mine were subjected to...

Copper-Based Bimetallic Catalysts for CO2 Hydrogenation to Methanol: Interfacial Synergy, Reaction Pathways, and Rational Design

CO2 hydrogenation to methanol is a key route for carbon recycling within the carbon capture, utilization, and storage (CCUS) framework. Cu-based catalysts are widely employed because of their low cost and high methanol selectivity, yet monometallic Cu suffers from sintering, limi...

Age- and Phenotype-Specific Patterns of Atopic and Autoimmune Comorbidities in Alopecia Areata: A Cross-Sectional Study

Background: Alopecia areata (AA) is frequently associated with atopic and autoimmune comorbidities, yet comprehensive data in Chinese populations remain scarce. We aimed to characterize the comorbidity landscape and identify predictors of the total comorbidity count in AA patient...

Comparative proteomics of human anterior lens capsules reveals ATP6V1A-associated lysosomal dysregulation in age-related cataract with primary angle-closure glaucoma

Lens-related mechanisms in primary angle-closure glaucoma (PACG) remain incompletely defined. The anterior lens capsule (ALC) is a biologically active interface, but its molecular landscape in PACG is largely unknown. We aimed to define proteomic alterations in human ALCs from ag...

Process Mineralogical Characterisation of Magnetite Ores in the Shilu Iron Mine, Hainan Province, South China

ABSTRACT The Shilu Iron Mine is one of China's largest high‐grade haematite deposits. Intense regional magmatism has also generated significant reformed magnetite ores. However, the underutilisation of these resources has led to resource waste. This study analyses representative...

Dual-Component Coating Enables Stable 4.6 V Cycling of High-Voltage LiCoO2 Cathodes

Abstract Lithium cobalt oxide (LCO) cathode materials are widely used in 3C electronic products but suffer from rapid capacity fading at high voltages (>4.2 V). We propose a synergistic LiF/ZrO2 double-coating strategy to construct a flexible-rigid intimately intermingled nano-mo...

Vessel-like Channeled Superelastic and Biocompatible Aerogels for Acoustic Absorption and Oil Removal

Abstract Modern industrialization and urbanization have led to environmental challenges, including noise pollution and water contamination, which threaten ecosystems and human health. Current materials designed to address these issues are limited in performance and functionality....

Business Strategy and Corporate Waste Outcomes: The Moderating Role of Board Gender Diversity

ABSTRACT Firm‐level drivers of corporate waste remain underresearched relative to other sustainability topics, such as carbon emissions and environmental, social, and governance (ESG) disclosure. Moreover, the role of female directors on corporate boards in this realm is also und...

The Interfacial Proton-Transfer Pathway Boosted Acidic Oxygen Evolution

Abstract Developing efficient and durable acidic oxygen evolution reaction (OER) catalysts for the proton exchange membrane water electrolyzer (PEMWE) is made challenging by sluggish proton transfer. Here, we engineer a fluorinated carbon-coated Co3O4 (F/C–Co3O4) interface based...

Outcomes of the modified Woodward procedure with and without concomitant clavicular osteotomy and intraoperative neurophysiological monitoring for Sprengel deformity: a retrospective cohort study with a minimum 2-year follow-up

Surgical treatment of Sprengel deformity aims to improve shoulder symmetry and active shoulder motion while avoiding neurovascular injury. Whether clavicular osteotomy should be added to the modified Woodward procedure remains controversial, particularly because intraoperative ne...

Descriptor completion and cascade transfer for strength prediction in high strength steels

Abstract Accurate prediction of tensile strength (TS) and yield strength (YS) in high-strength steels (HSS) is hindered by incomplete microstructural reporting in literature-derived datasets, even though mechanical behaviour is governed by strong composition-process-structure-pro...

Exposure to Size-Fractioned Ambient Particles Associated with Alterations in Gut Microbiome and Pro-Atherosclerotic Biomarkers in Young Adults

Abstract Background: Ambient fine and ultrafine particles are linked to the progression of atherosclerotic cardiovascular diseases, wherein gut microbiome may play a critical role. However, the underlying mechanisms and relevant metabolic pathways are not yet fully understood. Ob...

Neural-specific UBAP2L deficiency causes developmental delay and cortical abnormalities in mice

Rare UBAP2L variants have been linked to neurodevelopmental disorders (NDDs), such as autism spectrum disorder (ASD), but the role of UBAP2L in brain development remains unclear. Here, we generated neural-specific conditional knockout mice for Ubap2l using Nestin-Cre system, incl...

Adding salt to foods, genetic susceptibility, and risk of incident osteoporosis

Objectives To investigate the association between the frequency of adding salt to foods and incident osteoporosis and assess effect modification by genetic susceptibility. Design Prospective cohort study. Setting UK Biobank, United Kingdom. Participants 491,428 participants free...

Multi‐Omics Genome‐Wide to Explore the Formation and Development Targets for Intracranial Aneurysms

Intracranial aneurysms (IAs) represent a significant and potentially life-threatening category of disease, and there is currently a lack of effective treatment options aimed at preventing the progression of the disease. Accordingly, this study is dedicated to exploring and identi...

Photocatalytic Synthesis of Medium-Sized Lactams via Cascade Ring Expansion Reaction of Unstrained Cyclic Amines with NHC-Borane

Abstract Medium-ring lactams are important structural motifs in many scientific fields but are difficult to synthesize due to unfavorable entropic/enthalpic effects and transannular interactions. Herein, an efficient strategy for accessing highly functionalized borylated 9- to 11...

Double Adjustable‐Loop Cortical Buttons for Minimally Invasive Anatomic Double‐Bundle Medial Patellofemoral Ligament Reconstruction

Abstract Recurrent patellar dislocation is a common condition in young and active individuals, with medial patellofemoral ligament (MPFL) injury being the primary pathological factor in most cases. Anatomic double‐bundle MPFL reconstruction has been established as an effective tr...

Association between post-exercise heart rate recovery and one-year clinical deterioration in COPD: a retrospective longitudinal analysis

The application of cardiopulmonary exercise testing (CPET) for assessing heart rate recovery at 1 min (HRR1) is of significant clinical value in evaluating disease severity, cardiovascular risk, and prognosis in patients with cardiovascular diseases. However, its utility in patie...

Observation of Highly Efficient Electric-Quadrupole Second Harmonic Generation in a Dirac Semimetal

Abstract Topological semimetals hold great promise for nonlinear optics (NLO). It is challenging to probe tilted Dirac fermion-driven intrinsic second harmonic generation (SHG) and topological band structure modulation of second-order nonlinearity in spatial inversion and time-re...