Central South University

Null controllability for degenerate parabolic equations with internal control applied on a measurable subset

This paper investigates the null controllability of a class of two-dimensional linear parabolic equations with a boundary degeneracy on the domain Ω = 𝕋 × ( 0 , 1 ) , where the internal control acts on a space-time measurable subset of positive measure. Unlike conventional open c...

Interfacial Electronic Reconstruction in SnS2/CoS Heterostructure for Efficient Electrochemical Nitrate-to-Ammonia Conversion and Energy–Environment Integration

Abstract Electrocatalytic nitrate reduction reaction (NO3RR) provides a promising route for sustainable ammonia synthesis but is often limited by sluggish reaction kinetics, inefficient charge transfer, and competing hydrogen evolution. Herein, a SnS2/CoS heterostructure with str...

Integrated multi-omics decodes the AKI-to-CKD transition: from ensemble discovery to structure-guided translational targeting

The transition from acute kidney injury (AKI) to chronic kidney disease (CKD) constitutes a major global health burden. Identifying causal drivers remains challenging due to proteomic complexity and confounding biases. We aimed to construct a discovery framework to identify actio...

Clinical features and prognostic factors in paediatric medulloblastoma: a retrospective cohort study

To evaluate the clinical characteristics, outcomes, and prognostic factors associated with paediatric medulloblastoma (MB). We retrospectively analysed paediatric MB patients treated at Xiangya Hospital Central South University from January 2015 to July 2023. Overall survival (OS...

Experimental study on shear performance of wet joints with free-form surface shear keys in bridges

Wet joints in precast bridge decks are subjected to complex stresses and are vulnerable to cracking, with interface shear being a major damage mechanism. This study proposes a parametrically generated free-form surface shear key based on an even quartic interpolation profile. Hyb...

Tunnel face extraction method for drill-and-blast tunnels considering occlusion and blur degradation

Reliable extraction of tunnel-face regions is essential for image-based rock-mass interpretation and intelligent construction control in drill-and-blast tunnels. However, field images are often degraded by machinery and worker occlusions, invalid backgrounds, uneven illumination,...

Near‐Infrared Carbon Dots: From Precursors and Synthesis to Luminescence Mechanisms and Multifunctional Applications

ABSTRACT Carbon dots (CDs) are emerging zero‐dimensional carbon‐based nanomaterials with unique optical properties. Among them, near‐infrared carbon dots (NIR‐CDs), exhibiting absorption/emission in the biological transparency window (650‐1700 nm), have attracted increasing atten...

Mechanical Behavior and Stability Analysis of Underground Excavation Construction: Case Study of Large-Span and Variable Cross-Section Subway Crossover Tunnel

This paper presents a case study on the deformation characteristics and stress evolution of a large-span variable cross-section crossover tunnel excavated by the mining method. Three construction alternatives are compared: Scheme 1 adopts staggered excavation of twin tunnels with...

Glycosides from Cistanche tubulosa suppress intestinal ACSL4-mediated ferroptosis to ameliorate depression with intestinal dysfunction symptoms through regulating arachidonic acid metabolism

Abstract Background Depression is highly comorbid with intestinal dysfunction, yet antidepressant therapies are limited by suboptimal efficacy and frequent gastrointestinal adverse effects. Existing cellular and animal data support the potentially dual protective effects of total...

Common SAEs and their impact on the prognosis of children treated with the CCCG-ALL-2015 protocol: a retrospective multicentre Chinese study

This study was intended to evaluate common serious adverse events (SAEs) and analyze their effects on the prognosis of acute lymphoblastic leukemia (ALL) children. We retrospectively collected the data of 7640 consecutive ALL children with/ without SAEs who were enrolled in CCCG-...

Precision Selection for Targeted Radionuclide Therapy in Prostate Cancer: Biparametric MRI Radiomics Combined with Serum Bone Turnover Biomarkers for Predicting Postoperative Bone Metastasis

Objective: Particularly for patients with bone-dominant illness, targeted radionuclide treatments are becoming a viable treatment option for metastatic prostate cancer (PCa). Precision treatment selection and improved therapeutic outcomes may result from early detection of patien...

Development and validation of a risk prediction nomogram model for re-enrollment intentions in adolescent depression patients on academic leave: a cross-sectional study

Abstract Background Depression is prevalent among adolescents and can result in academic leave, and these individuals may face difficulties when returning to school. This study aimed to investigate re-enrollment intentions among adolescent depression patients on leave, identify i...

Land-Use Change, Ecosystem Services, and Ecological Security Pattern in a Mineral Resource-Based City: A Case Study of Chenzhou, China

Mineral resource-based cities face long-term conflicts among resource exploitation, urban expansion, and ecological conservation, making it necessary to clarify how long-term land-use change affects ecosystem services and ecological security patterns. Taking Chenzhou, China, as a...

Characteristics, treatment patterns, and outcomes of patients with transthyretin amyloidosis: a large-scale, observational, retrospective study in China (OverTTuRe China)

Abstract Background Evidence remains limited on disease journey for transthyretin (ATTR) amyloidosis in China. This study aims to analyse China data from OverTTuRe, an observational, retrospective, multi-country cohort study. Methods Data were extracted from medical records (2013...

Corporate disclosures of carbon-reduction actions and firm value: the moderating role of digital transformation

Purpose This study examines whether corporate disclosures of carbon-reduction actions are associated with firm value under China's “dual-carbon” strategy. It further compares the valuation relevance of internally oriented operational disclosures and value-chain-oriented disclosur...

Rheological Response, Strength Development and Conditional Age-Progressive Strength Updating of Cement Kiln Dust-Modified Cemented Tailings Backfill

Cement kiln dust (CKD) can partially replace Portland cement in cemented tailings backfill, but its application must satisfy both pipeline transportability and mechanical strength requirements. This study aims to evaluate the rheological and mechanical evolution of a low-carbon C...

Automatic segmentation of malignant pulmonary nodules on LUNA16 subsets using an attention-guided 3D U-Net framework

Objective Lung cancer is the leading cause of cancer-related mortality worldwide, and accurate segmentation of malignant pulmonary nodules is essential for quantitative lesion analysis and computer-aided lung cancer screening. Manual segmentation is time-consuming and highly depe...

Facilitators and barriers influencing the implementation of type 2 diabetes remission programmes: a qualitative meta-synthesis from a multi-stakeholder perspective

Although type 2 diabetes (T2D) remission has emerged as a promising therapeutic goal, its implementation in real-world settings faces considerable challenges. Understanding the perspectives of multiple stakeholders is essential to address these implementation challenges. This met...

High sperm DNA fragmentation is associated with increased embryonic chromosomal abnormality: a retrospective study of 8 years involving 5637 couples undergoing ART

Abstract STUDY QUESTION Does sperm DNA fragmentation impair blastocyst chromosomal integrity? SUMMARY ANSWER A high sperm DNA fragmentation index (DFI) is associated with an increased risk of blastocyst aneuploidy, particularly when the man has poor semen quality or when the fema...

Low-Shrinkage 3D-Printed Polymeric Microneedle Arrays with Electroless Silver Coating for Enhanced Thermal and Mechanical Performance in Dermatological Applications

Microneedling has found various applications in dermatology recently. However, many problems still need to be solved in the fabrication of high-aspect-ratio polymeric microneedles with good mechanical strength, dimensional accuracy and thermal conductivity for energy-assisted tre...