Central South University

Neutropenia events with androgen receptor pathway inhibitor-containing versus control therapies in prostate cancer patients: a systematic review and meta-analysis

To systematically evaluate the risk of neutropenia associated with androgen receptor pathway inhibitor (ARPI) intensification in patients with prostate cancer across phase 3 randomized controlled trials. This systematic review and meta-analysis was conducted in accordance with PR...

Vacuum‐Assisted Impurities Removing Triggered Electronic Configuration Reconstruction of Spent NCM for Ultrafast Lithium Storage

ABSTRACT Attracted by ∼100% element recovery rate, direct regeneration of spent NCM (SNCM) has been deemed as next‐generation recycling strategy. However, practical SNCM is always mixed with inactive impurities (PVDF and conductive carbon), which introduces undesirable heteroatom...

Synergistic Heterointerface Engineering and Light‐Assisted Enhancement in NiSe/SnSe Anodes for Ultra‐Stable and High‐Rate Sodium‐Ion Batteries

ABSTRACT Sodium‐ion batteries (SIBs) face challenges from sluggish kinetics and volume expansion due to the large Na + radius. Herein, we design a carbon‐coated porous NiSe/SnSe@NC Schottky heterojunction via in‐situ synthesis. The epitaxial growth ensures lattice matching, estab...

Clcn6 mRNA and ClC-6 protein expression in mouse central nervous system

To investigate the expression patterns of Clcn6 mRNA and ClC-6 protein in postnatal mouse of distinct region of central nervous system (CNS) and developmental stages. Distinct CNS regions, including cerebral cortex, hippocampus, cerebellum, brainstem, olfactory bulb, hypothalamus...

The therapeutic effect of genistein on microfracture based on network pharmacology, immune cell abundance analysis and experimental verification

Postmenopausal osteoporosis is a metabolic bone disease mainly attributed to estrogen deficiency. Genistein, a major phytoestrogen, has been reported to exert a direct suppressive effect on osteoclasts. The aim of this study was to explore the possible impact of genistein on oste...

Appetitive trait profiles in late life: links to eating disorder psychopathology and psychosocial well-being

Abstract Objective Appetitive traits shape eating behaviors across the lifespan, yet their patterns and health correlates in later life remain poorly understood. This study used latent profile analysis (LPA) to identify distinct profiles of appetitive traits among older adults an...

Phase Transition Mediated Solvation Structure Regulation in Quasi‐Solid‐State Composite Electrolyte for High‐Voltage Sodium Batteries

ABSTRACT Quasi‐solid‐state composite electrolytes (QSSEs) represent a promising approach to fabricating high‐energy rechargeable batteries, but their practical implementation is hindered by structural instability and interfacial incompatibility. In this study, a QSSE was prepared...

Synthesis of a novel cationic short-chain fluorocarbon surfactant and its synergistic effect with hydrocarbon surfactants for enhanced foam performance

Short-chain fluorocarbon surfactants are key alternatives to long-chain fluorocarbon surfactants, while the research on their cationic formulations remains limited. This study synthesizes a novel quaternary ammonium cationic short-chain fluorocarbon surfactant ( PFH-QAC ) and enh...

International Advisory Committee Certificate-En-Bing Lin

Dr. En-Bing Lin, made a valuable contribution as a Member of the International Advisory Committee, for AgriTech-One 2026 Conference, organized by Scientiae-Naturalis.org, providing expert advice and guidance on the planning and implementation of the 3rd AgriTech-One Scientific Co...

Multicenter Privacy‐Preserving Federated Models for Predicting Postoperative Delirium and Acute Kidney Injury in Older Patients

ABSTRACT Postoperative delirium (POD) and acute kidney injury (AKI) are serious complications in older patients undergoing surgery, yet predictive model development is often constrained by single‐center data limitations and privacy concerns that preclude centralized data sharing....

Oncogenic USP3 promotes hepatocellular carcinoma progression via K11/K48-specific deubiquitination and stabilization of YAP

Hepatocellular carcinoma (HCC) has a poor prognosis, necessitating therapeutic targets, while the role of ubiquitin-specific protease 3 (USP3) in HCC remains unclear. This study aimed to elucidate the function of the deubiquitinating enzyme USP3 in HCC. USP3 was found to be highl...

Chinese Painting Semantic Resource for Resolution-Aware Digitisation and Structured Heritage Access

Chinese painting digitisation poses a distinctive heritage-informatics challenge: culturally salient visual structures such as brushwork, intentional blank space, and text–image coexistence are difficult to document, access, and research with general-purpose collection and comput...

Immune-inflammatory biomarkers for in-hospital mortality risk stratification in older patients with sepsis: a multicentre leave-one-hospital-out validation study

Older adults with sepsis have high mortality, but whether circulating immune-inflammatory biomarkers improve prediction beyond routine clinical information across hospitals is uncertain. We analysed 816 patients aged ≥ 60 years from a prospectively assembled multicentre cohort at...

Nomogram model based on dual-energy CT quantitative parameters and radiomics for preoperative prediction of microvascular invasion in hepatocellular carcinoma

Abstract Objective To explore the potential value of a nomogram model based on dual-energy CT (DECT) quantitative parameters and radiomics for preoperative prediction of microvascular invasion (MVI) in hepatocellular carcinoma. Methods A retrospective analysis was conducted on 14...

Primary central nervous system histiocytic sarcoma with skull base and ventricular dissemination: a case report and literature review

Abstract Purpose The primary objective of this case report is to highlight the clinical challenges and diagnostic difficulties of histiocytic sarcoma (HS) involving the central nervous system (CNS). This case emphasizes the importance of accurate diagnosis in patients presenting...

Comparison of three interpretation criteria for [⁶⁸Ga]Ga-DOTATATE PET/CT in suspected pheochromocytoma and paraganglioma of the adrenal gland or retroperitoneal space

Pheochromocytomas and paragangliomas (PPGLs) frequently overexpress somatostatin receptor subtype 2 (SSTR2), making [ 68 Ga]Ga-DOTATATE PET/CT a promising functional imaging modality. However, the optimal interpretation criteria for distinguishing PPGL from non-PPGL lesions in cl...

Comprehensive multi-omics landscape exploration and functional characterization of TACSTD2 throughout pan-cancer

Tumor-associated calcium signal transducer 2 ( TACSTD2 ) is widely investigated in cancer research. Its overexpression across multiple cancers is linked to elevated tumor aggressiveness, metastasis, and poor prognosis, making it a potential biomarker for diagnosis, prognosis, and...

Integrated GWAS Candidate Prioritization, Moso Bamboo Transcriptome Screening and Diverse Bamboo Shoot Multi-Omics Reveal a Multi-Layer Framework for Bamboo Property Formation

Bamboo shoot development influences subsequent culm architecture and material properties, but the biological relevance of GWAS-derived candidates remains unclear. A stepwise candidate-prioritization strategy integrated 99 previously reported property-associated candidates with la...

MTAP deficiency in lung cancer cells enhances proliferation and migration and increases vulnerability to bone metastasis

Lung cancer continues to be the leading cause of cancer-related death worldwide. The advent of molecular targeted therapies has significantly changed the treatment landscape. Therefore, identifying new molecular targets is essential for the development of more effective treatment...

Expression of LDHA, Pan-Kla Level and H3K18la associates with clinical progression of laryngeal squamous cell carcinoma

Laryngeal squamous cell carcinoma (LSCC) represents one of the major subtypes of head and neck squamous cell carcinoma (HNSC), imposing substantial health burdens and necessitates comprehensive clinical interventions. Lactylation, a newly discovered protein post-translational mod...