Research works

High-resolution magnetic resonance angiography for predicting short-term prognosis in young patients with atherosclerotic stroke: a mediation analysis based on middle cerebral artery plaque characteristics

Abstract Objective This study primarily evaluated the predictive value of middle cerebral artery (MCA) plaque characteristics, assessed by high-resolution magnetic resonance vessel wall imaging (HR-VWI), for 90-day prognosis in young patients with atherosclerotic ischemic stroke....

A consortium-driven framework for biomarker prioritization in the HEBE aging study

Abstract Aging is a complex biological process influenced by chronic low-grade inflammation, oxidative stress, and metabolic dysregulation, collectively termed inflammaging. The HEBE (Healthy aging versus inflamm-aging: the role of physical Exercise in modulating the Biomarkers o...

Monograph E: Machine Ahimsa

This monograph formalizes "Machine Ahimsa," an operator-theoretic analysis of non-harm mechanics and custodial governance applied to synthetic, artificial, and recursive computational substrates. The study resolves a critical vulnerability in modern AI safety and legal jurisprude...

UBE2K-FBXO11 complex activates Wnt signaling by stabilizing β-catenin through lysine 63-linked polyubiquitination

Abstract Β-catenin is regulated by phosphorylation and lysine (K)48-linked ubiquitination, which target it for proteasomal degradation. While the degradation machinery of β-catenin, including the destruction complex, has been extensively studied, regulators that stabilize β-caten...

Comparative Analysis of Media Exclusions and Press Access Restrictions by U.S. Presidents: The First Amendment, the Dynamics of the White House Press Corps, and the Weaponization of Antitrust Enforcement

Description (Abstract): This comprehensive research monograph provides a comparative institutional and constitutional analysis of the structural tensions between the executive branch of the United States and the press, focusing specifically on presidential attempts to ban, exclud...

MS-CAFNet: enhancing 3D point accuracy of laser scanners through a multi-stage self-attention network for applications in construction

Abstract We propose the MS-CAFNet algorithm, featuring an integrated pipeline that combines per-room geometric registration with a multi-stage convolutional network and symmetry test-time augmentation. This method enables the reduction of 3D point accuracy uncertainty associated...

Exploring transcriptomic and genomic latent variable correction approaches in differential expression analysis

Abstract Background Differential expression analysis is a central tool for studying the biological processes altered in human diseases via transcriptomic signatures. However, transcriptomic datasets are systematically confounded by latent variables from two distinct sources: unme...

A comparative investigation on molten salt hot corrosion of GTA and SMA-welded super-heater pipes of 70 MW CFBC boilers

Abstract The tubular SA 335 P91 joints are generally used as super-heater pipes in CFBC boilers. This research work presents hot corrosion studies on similar SA 335 P91 joints using ErNiCrMo-3 and E9018 B9 fillers via GTAW and SMAW. The HTC studies were conducted at 770 ± 1˚C emp...

Integrating chromic responsiveness with conventional performance toward multifunctional smart fibers for applied technologies

Abstract Stimuli-responsive wearable textiles with reversible colorimetric changes have been crucial for various applications, such as healthcare monitoring, camouflage, energy-saving building materials, and sensing. Rapid technological advancements have led to a diversity of sma...

Forest carbon certification under climate and mortality uncertainty: ecological and economic trade-offs of management scenarios in Freiburg, Germany

Abstract Background Forest carbon certification could help finance the transformation of climate-sensitive stands, but early interventions may reduce biomass and timber revenue before carbon and ecological benefits emerge. Evidence that jointly evaluates forest growth, hydrologic...

Local capital geometry for maxmin concavification (C73-17)

A local-capital-geometry characterization of equality between the informed-player maxmin and concavification at every prior. The additional Lean project formalizes the criterion using the nonrevealing lower value; its README explains the relationship to the complete-information g...

Management of hemodynamically stable penetrating chest trauma without cardiac injury in Marseille

Abstract Background Penetrating chest trauma (PCT) is uncommon in Western Europe but carries substantial morbidity. Non-operative treatment (NOT) is widely practiced in regions with high rates of penetrating injuries, whereas European centers continue to report higher surgical ex...

Multiple discrimination at work and depressive symptoms in young adults

BACKGROUND: We aimed to estimate the implications of cumulative exposure to discrimination at work for mental health among young adults. Our specific objective was to investigate if experiencing multiple types of discrimination at work is associated with depressive symptoms. METH...

Integrating the social and solidarity economy into global health: towards structural transformation for equity, resilience, and sustainability

Abstract Global health is shaped by complex and interdependent challenges across social, commercial, environmental, technological, and political domains that cannot be solved by the health sector alone. In response, alternative economic models and paradigms have gained attention....

Bridging policy and implementation science: operationalising political and structural determinants for health policy implementation evaluation

Abstract Background Despite their critical role in shaping public health policy implementation, key political and structural determinants within implementation frameworks are often poorly defined, underreported, or treated as background rather than as core implementation variable...

Prediction of early radiological response in esophageal cancer using CT radiomics and clinical factors: a single-center proof-of-concept study in an elderly cohort

Abstract Background To develop, as a proof-of-concept analysis, a machine learning model predicting early radiological treatment response in an elderly, single-center esophageal cancer (EC) cohort, and to test whether adding clinical factors to CT radiomics improves prediction. M...

Predictive performance of clinical, physiological, and trauma scores for life-saving interventions in pediatric trauma: a retrospective cohort study

Abstract Background Early identification of pediatric trauma patients requiring life-saving interventions (LSIs) is fundamental for optimizing emergency triage and allocation planning. This study aimed to evaluate and compare the predictive effectiveness of the Abbreviated Injury...

Object groups mutually bias each other’s perceived average size, as evidenced by neural and behavioural data

Abstract The human visual system simultaneously computes summary statistics of object features, such as average size, across groups of objects. Evidence suggests that summary statistics across groups of objects (ensembles) are not independent but influence one another. We investi...

Exact Degrees for a Fixed-Double-Pole Rational Hénon Family

We give an all-parameter degree calculation for the birational maps F(x,y)=(beta/x+gamma/x^2-delta*y,x) over the complex numbers, with gamma*delta nonzero. Outside the nontrivial root-of-unity resonances of -delta^3, the first dynamical degree is 2. At a resonance of order ell, t...

Sustainable iodine contrast media for a healthy future (SUSTAINED): a global survey of practice

Abstract Objectives To investigate healthcare professionals’ knowledge, attitudes, and practices (KAPs) of the environmental impact and sustainability of iodinated contrast media (ICM). Materials and methods A cross-sectional web-based survey was distributed to members of profess...