Research works

A Robust Mitochondria‐Targeted Photosensitizer Synergizes With Cisplatin Chemotherapy for Enhanced Antitumor Immunity

ABSTRACT Chemotherapy remains a major strategy for cancer treatment, with cisplatin widely used as a first‐line agent for diverse malignancies. Although cisplatin efficiently induces tumor cell death through DNA damage, its therapeutic efficacy is often limited by the development...

Processing Stability and Antioxidant Activity of Anthocyanins from Nitraria tangutorum and Lycium ruthenicum : A Comparative Study with Microencapsulation for Quality Retention

Abstract To address anthocyanin degradation during processing, this study investigated the stability and antioxidant activity of anthocyanins from Nitraria tangutorum (Qinghai) and Lycium ruthenicum from three origins (Qinghai, Gansu, Xinjiang), and evaluated the protective effic...

What Is Chronos Theory? A Plain-Language Guide to Time, the Temporal Field, and the Chronos Research Program

What Is Chronos Theory? is a plain-language introduction and research guide to the Chronos Theory program developed by Matthew J. Hall. Chronos begins from the proposition that time is physically meaningful and fundamental rather than something produced by motion, entropy, observ...

Holy Mary, Seat of Wisdom

This article examines the Marian title Seat of Wisdom (Sedes Sapientiae) on the basis of its biblical and theological foundations, especially the mystery of the Incarnation and Mary’s divine motherhood. It also explores its development in the Tradition of the Church, its presence...

Solvent‐Induced Structural Modulation in Nanoscale Covalent Organic Frameworks Enables High‐Performance NO 2 Sensing

ABSTRACT Covalent organic frameworks (COFs) offer exceptional structural and functional tunability, enabling performance optimization in separation, catalysis, and sensing applications. Here, we report a solvent‐induced strategy for inducing structural disorder in porphyrin‐based...

Responses of growth and quality of Glycyrrhiza uralensis to salt-alkali-tolerant microbial inoculant via the remodeling of rhizosphere microenvironments in moderate and severe saline-alkali soils

Abstract Glycyrrhiza uralensis is an ecologically and economically important medicinal species for saline-alkali land restoration in arid northwest China. Nevertheless, excessive soil salinity, alkalinity and nutrient deficiency substantially restrict its growth and degrade medic...

Promotion of Angiogenesis with American Ginseng ( Panax quinquefolius ) After Myocardial Infarction via Targeting DNMT3b-Mediated DNA Methylation and Activating the Notch1/USP5/STAT3 Signaling Axis

Myocardial infarction (MI) necessitates the promotion of angiogenesis to improve prognosis. Panax quinquefolius saponins (PQS), bioactive constituents of a medicinal and edible homologous plant, are known for their cardiovascular benefits, but their epigenetic mechanisms in post-...

Fuzzy AHP–TOPSIS framework for identifying barriers and strategies for integrated Lean–BIM adoption in the Indian construction industry

Purpose Lean construction (LC) and building information modelling (BIM) are viewed as complementary approaches for improving operational efficiency and value delivery in construction projects. Nevertheless, their combined implementation within the Indian construction industry rem...

BASE 44 ORDER: Implement dual-issue shader dispatch via E8 root vectors 1 and 2 — E8 Intelligence Research

Andrew's order (Base 44 console): [SELF-BUILD from enhancement #796] Implement dual-issue shader dispatch by aligning two inference pipeline stages with E8 root vectors 1 and 2. Modify scheduler to issue both stages simultaneously on root resonance. Test on eToro replay bench for...

Facile Ferric Nitrate Spray Fabrication and In Situ NAP-XPS Investigation of NiFeOxHy-Coated Nickel Foam Electrocatalysts for Alkaline Water Electrolysis

Abstract The development of efficient and scalable oxygen evolution reaction (OER) electrocatalysts is critical for advancing alkaline water electrolysis technologies. In this study, we present a facile spraying method for fabricating NiFeOxHy-coated nickel foam (NF) electrodes u...

Integrated Hydraulic and Mathematical Evaluation of Flat Sheet Polyamide Reverse Osmosis Membranes for Poultry Slaughterhouse Wastewater Treatment

Reuse of industrial wastewater contributes to the conservation of freshwater resources and the implementation of the principles of the circular economy. In this study, the cyclic performance of a flat-sheet polyamide reverse osmosis membrane (PA-RO) for the advanced treatment of...

Modular Access to α ‐Tertiary Amines: Electrochemical Tandem Di‐Functionalization of Olefins With Ammonia Surrogates and Amino Acids

ABSTRACT Quaternary carbon centers, especially those bearing nitrogen, are highly valued in drug discovery, imparting three‐dimensionality, selectivity, and metabolic stability. Yet, accessing α ‐tertiary, primary amines ( α ‐TPAs) remains challenging due to steric congestion and...

A comparative analysis of topic modelling techniques for the thematic analysis of student feedback

This study seeks best practices for when and how to apply short text topic modelling (STTM) techniques using natural language processing to semi-structured data collected as part of education research in order to provide accurate guidance for interventions and avoid misguided imp...

Dynamic Scaling Pollard’s P-1 Algorithm

The integer factorization problem is a hard problem in classical. Let N=PQ, where P and Q are large primes. Pollard’s P-1 Algorithm is an efficient integer factorization algorithm while all the prime factors of P−1 are small. However, the previous variants of Pollard’s P-1 algori...

Adjunctive oral naltrexone for breakthrough craving in patients receiving extended-release injectable naltrexone for alcohol use disorder: Three cases

Craving is a subjective, poorly characterized phenomenon strongly associated with return to use in alcohol use disorder and remains difficult to manage. Extended-release naltrexone is a U.S. Food and Drug Administration–approved, evidence-based treatment, yet some patients experi...

Glycemic and Lipid Outcomes Associated with Bitter Melon Blood-Sugar-Modulating Protein and Metformin Use: A Translational Preclinical and Retrospective Study

Background/Objectives: Interactions between botanical supplements and standard antidiabetic therapies remain poorly understood. This study investigated the efficacy and mechanistic properties of a bitter melon blood-sugar-modulating protein (BMP) in relation to concurrent metform...

Machine-Learning-Based Screening of Relative Eccentric-Wear Severity in Shield TBM Disc Cutters Using 3D-Scan Morphology Labels

Disc-cutter wear in abrasive strata is spatially non-uniform, yet mean wear depth cannot indicate where it concentrates. This retrospective feasibility study develops a machine-learning-based condition-monitoring framework that predicts the relative severity of eccentric wear fro...

Quantum approximate optimization algorithm with fixed number of parameters

We introduce a novel quantum optimization paradigm: the Fixed-Parameter-Count Quantum Approximate Optimization Algorithm (FPC-QAOA). It is a scalable variational framework that maintains a constant number of trainable parameters regardless of the number of qubits, Hamiltonian com...

The Dutch Prolactinoma Cohort Studies: Cross-sectional Analysis of Females Focusing on the Patient's Perspective

Abstract Purpose To assess the results of patient-reported outcome measures (PROMs) in a national cohort of females with a prolactinoma by disease activity. Methods Females with prolactinoma included in the PRolaCT or ProlaC study were assessed cross-sectionally, comparing patien...

A Rapid Method for the Identification and Screening of Bitter Compounds Using Moslae Herba as a Case Study

ABSTRACT Moslae Herba, a commonly used traditional Chinese medicine with both diaphoretic and diuretic properties, exhibits intense bitterness in its clinical decoction, which severely compromises patient compliance. As a highly representative and typical case among bitter‐tastin...