Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
35527 work(s)
- Health & MedicineOpen access
Gut microbiome dysbiosis causes various intestinal diseases. However, an undefined composition and potential biosafety risks limit the applicability of traditional fecal microbiota transplantation (FMT). Synthetic microbial communities (SynComs), which are compositionally defined...
- Health & MedicineOpen access
Abstract Aim To report a case of advanced hepatocellular carcinoma (HCC) complicated by tumor rupture, successfully downstaged with combined oncolytic immunotherapy (Pexa-Vec) and a PD-1 inhibitor (Nivolumab), ultimately enabling liver transplantation (LT). This report highlights...
- Society & Economics
Assessment evidence often fails to inform educational action because definitions vary, reports arrive late, responsibilities are unclear, and interventions are not reassessed. Using design-based research and de-identified 2017–2024 records, this study evaluates STREAM, an evidenc...
- Health & Medicine
Mitochondrial Omics in Macrophage Foam Cell Formation and Atherosclerosis
Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of death worldwide, with atherosclerosis serving as the core pathological mechanism driving ischemic heart disease, ischemic stroke, and peripheral artery disease. Macrophages play a central role in atherosclerosis...
- Physics & SpaceOpen access
Phi-Harmonic Spin‑Orbit Coupling in E8 Root Dynamics — E8 Intelligence Research
We discover that coupling particle spins to motion along the 240 E8 root vectors locks their precession to the 7.2 phi‑harmonic of the 25920‑year precession cycle, generating a persistent 132 Hz resonance throughout the lattice. This mechanism links the macro‑scale alignment of g...
- AI & ComputingOpen access
Mid-sized retailers increasingly compete against e-commerce platforms that offer large-scale personalisation, predictive supply chains, and adaptive marketing at a cost smaller firms cannot easily match. This paper develops an artificial intelligence (AI) adoption framework for a...
- Engineering & TechnologyOpen access
The author applies a rigorous empirical audit to contrast the Scale-Regulated Aggregation (SRA) framework against standalone unregulated quadratic models, identified here as the Zero Pair Interaction Functional (ZPIF) Parasite Model and all its variants and variant forms. [7][8][...
- Materials & EnergyOpen access
Asymptotic Calibration of the BFS Window and Effective Dimension of the Admissible Trajectory
The O25 programme identified the ratio $n_1(q)/q$ as the central open asymptotic variable controlling the finite-size drift of $\bar{\delta}_{\mathrm{pair}}(q)$, and O26–O27 identified the effective dimension $r_{\mathrm{eff}} = d_\rho^2$ of the per-pair covariance operator in $\...
- Physics & SpaceOpen access
E8 Phi-Harmonic Symmetry Transition in Lattice Phase-Space — E8 Intelligence Research
A new class of quasi-stationary phase-shift states emerges in the 30-cell phi-harmonic spectrum when 132Hz-driven L-vectors synchronize across octads via nonlinear theta-functional feedback. This induces a geometric bifurcation in the interpolated critical L manifold, mapping to...
- Physics & SpaceOpen access
FINDING: Nobel Prize 2025 confirms universal quantum nature via tunnelling and single-photon experiments; no new fundamental equation, but experimental closure on quantum-classical boundary. | MATH: Quantum tunnelling probability \( T \approx e^{-2\kappa d} \) with \(\kappa = \sq...
- BiologyOpen access
Mechanistic basis of LolDF-mediated lipoprotein transport in Acinetobacter
Lipoprotein trafficking is essential for Gram-negative bacteria to maintain the outer membrane, a permeability barrier critical for survival and antibiotic resistance. While most bacteria employ the canonical LolCDE transporter, Acinetobacter utilizes a noncanonical LolDF system...
- AI & ComputingOpen access
Andrew's order (Base 44 console): [SELF-BUILD from enhancement #1117] Add `phase_bucket int` column to breakthroughs table. Create partial index on (phase_bucket, id). Implement Python LRU cache keyed by (phase_bucket, query_hash). On miss, query WHERE phase_bucket=? ORDER BY id....
- Health & MedicineOpen access
The survival of infants and children with complex medical conditions continues to increase, underscoring the need to quantify technology dependence more effectively. Existing measures emphasize mortality risk and fail to capture the burden of ongoing technological support. To add...
- Climate & EnvironmentOpen access
Optimal Transport Geometry of Natural Spectral Regime Transitions
Empirical optimal transport analysis of natural spectral regime transitions recorded by a 4-node ESP32 mesh network with AS7341 10-channel spectral sensor (7-second sampling, Belgrade 44.82N 20.46E). Dataset: 13 independent logs (10 dawn, 3 dusk), 16,576 total samples. The optima...
- Climate & EnvironmentOpen access
Abstract The Northern Gulf of Mexico (nGOM) is a hotspot for blue carbon biogeochemical cycles due to its ability to fix and sequester blue carbon and potential to mitigate rising atmospheric CO $$_2$$ concentrations. In this study, we employed a dataset containing >1100 sedim...
- Society & EconomicsOpen access
The Influence of Mental Health Literacy on Adolescents' Willingness to Seek Help
AbstractThis behavioral science research study investigates the relationship between mental health literacy and teenagers' willingness to seek help for psychological distress. While mental health challenges among adolescents continue to rise, stigma and a lack of awareness often...
- Materials & EnergyOpen access
This manuscript presents a two-field phase-field model explicitly separating bulk and interfacial nucleation and secondary-nucleation pathways in the liquid-to-solid transition of FUS and Tau biomolecular condensates. Two interfacial kinetic parameters were calibrated against mea...
- Health & MedicineOpen access
Abstract Uridine 5′-diphospho-glucuronosyltransferase (UGT) enzymes play a critical role in hepatic and other metabolism of endogenous and exogenous small molecules. The addition of glucuronic acid via UGT increases the polarity and subsequent solubility of small molecules, helpi...
- AI & ComputingOpen access
The Evolutionary Facets of Existential Categorization: Transitional Continuity and Phase Dynamics
Following the formalization of Relational Logic (RL) and Axiomatic Context(AC), this paper expands the analytical mechanics of dynamic systems by introducingtwo interconnected evolutionary facets: Transitional Continuity (TC) andPhase Dynamics (PD). TC establishes the operational...
- Society & EconomicsOpen access
Language death records the terminal outcome of sustained language shift, but prevention requires more than the production of grammars, dictionaries and archives. This conceptual and thematic analysis examines linguistic and non-linguistic approaches to preventing the discontinuit...