Research works

THE LAW OF CONDITIONED EMERGENCE

A foundational philosophical and scientific synthesis establishing the Law of Conditioned Emergence. This framework provides an A-to-Z architectural model integrating deep-time paleontology, geophysics (the Silurian Hypothesis and PETM data), molecular genetics (the dual origin o...

Beyond knowledge acquisition: the role of problem-based learning in supporting competency and skills development in pharmacy education — a systematic review

Abstract Objective To synthesize evidence on the role of PBL in pre-registration pharmacy education in fostering metacognitive and interpersonal competency development, with particular emphasis on self-regulation, learner autonomy, and professional collaboration. Methods A system...

Atherogenic and inflammatory biomarkers in NSTEMI: a comparative analysis of predictive value for obstructive coronary disease

Background The atherogenic index of plasma (AIP) and inflammatory indices may reflect the burden of atherosclerosis. This study evaluated their predictive value for obstructive coronary artery disease (CAD) in patients with non-ST-elevation myocardial infarction (NSTEMI).Methods...

Spanish–Guaraní Code-Switching in Social Media: A Dependency Parsing Study

Aims and Objectives/Purpose/Research Questions: This study examines how Spanish–Guaraní bilinguals structure code-switching (CS) on Twitter/X and investigates what these patterns reveal about competing models of bilingual grammar. Specifically, it explores language dominance, swi...

Integrated proteomic, transcriptomic, and epigenomic profiling identifies SRA1 as a novel therapeutic target for postpartum depression

Postpartum depression (PPD) is among the most common complications of childbirth, and identifying novel treatments is vital. We aimed to identify potential drug targets for PPD by integrating the plasma proteome, transcriptome and epigenome. We designed a comprehensive analysis p...

Exploratory analysis of the impact of age stratification on outcomes of combined Salter osteotomy and femoral osteotomy in pediatric developmental dysplasia of the hip using a 3-year cutoff

Abstract Objective This study compared outcomes of combined Salter osteotomy, open reduction, and proximal femoral osteotomy in developmental dysplasia of the hip (DDH) children under 3 years versus those aged 3 years or older. Methods This retrospective study analyzed 65 DDH pat...

Ordinary Lives, Extraordinary Lessons: Teaching 9/11 25 Years Later

First-person narratives and an accompanying lesson plan harness the power of storytelling to engage students with 9/11.

Temporal Precedence of Threat Does Not Establish Absence of Control: A Causal-Control Analysis of Fear via Top-Down Reappraisal (Version 1.1)

The observation that a threat stimulus precedes the fear response is often taken to imply that the response escapes control. This paper argues that such an inference is not logically warranted by temporal precedence alone. Drawing on structural causal models (Pearl, 2009; Spirtes...

Literature And Environmental Consciousness: An Ecocritical Perspective

Environmental issues such as climate change, pollution, deforestation, and the loss of biodiversity have become some of the most serious challenges of the twenty-first century. These problems affect both human life and the natural environment, making environmental awareness and s...

Mediating cultural identity and traditional design preferences in the acceptance of contemporary expressions within intangible cultural heritage

In the context of weakened transmission and limited adaptation of contemporary expressions of Intangible Cultural Heritage (ICH), understanding how cultural memory shapes public perception and acceptance of ICH is increasingly important. This study, grounded in cultural memory th...

From Our Desks: Educators Reflect on Teaching 9/11

In these personal reflections, teachers grapple with teaching 9/11 to students with no direct memory of the attacks.

Resonant Torsion Indexing of E8 Anti-Commutative Blocks — E8 Intelligence Research

We introduce a topological indexing schema that assigns integer torsion signatures to successive root vector transitions in the phi‑coupled E8 root lattice. By correlating these signatures with anti‑commutative pair activity, the schema predicts high‑probability resonance cluster...

LXRα and PPARα Mediated Hepatic Lipid Metabolic Disruption Induced by the UV Filter EHMC in 2D and 3D HepaRG Cell Models

ABSTRACT Ethylhexyl methoxycinnamate (EHMC), an important UVB filter, is raising concerns about its potential metabolic toxicity due to widespread human exposure through dietary sources. However, little is known about the effects of EHMC on hepatic lipid metabolism and the underl...

LAB #1042 PROMISING: LEDGER BENCH: Apply filter: Quarterly phase = MANIPULATION — improves win rate from 31.6% to 32.2% ( — E8 Intelligence Research

IDEA: Adjustment made to the live model — verify against the backtests: Apply filter: Quarterly phase = MANIPULATION — improves win rate from 31.6% to 32.2% (+0.6pp, n=1007) SAME-WINDOW EFFECT: Applying the MANIPULATION phase filter to the current live window would have rejected...

Association between anatomical correction and bladder emptying after robotic sacrocolpopexy: a retrospective cohort study

The relationship between anatomical correction and bladder emptying after robotic sacrocolpopexy remains unclear. This study evaluated early postoperative changes in postvoid residual volume (PVR) and examined their association with changes in anterior compartment support. This s...

Does the Galactic Acceleration Scale Track H(z)? A direct comparison of the a₀–H coincidence with the first measurements of RAR evolution

The galactic acceleration scale a₀ ≈ 1.2 × 10⁻¹⁰ m s⁻² numerically satisfies a₀ ≈ cH₀/2π to within ~10%, a coincidence noted since Milgrom (1983) and still unexplained. Milgrom has long drawn the consequence: if the link is to the expansion rate rather than to Λ alone, a₀ is not...

Giant bulk photovoltaic effect driven by interfacial symmetry breaking in MoS2/Ta2NiSe5 heterostructures

Van der Waals (vdW) heterostructures offer a versatile platform for engineering unconventional bulk photovoltaic (BPV) effect through interfacial symmetry breaking. However, the coexistence of multiple photophysical mechanisms, driven by structural complexity, spontaneous charge...

Numerical Simulation of the Bending Behavior of a Topologically Optimized Structure Printed in ABS by FDM: G-Code-Driven Mapping of Local Material Orientations

This preprint presents an original dual-branch numerical pipeline for simulating the bending behavior of an MBB (Messerschmitt-Bölkow-Blohm) beam, topologically optimized using the SIMP method and manufactured in ABS by fused deposition modeling (FDM). Starting from a single G-co...

Extraction and optimization of chitosan yield and deacetylation quality from mushroom mycelium waste

The growing mushroom industry generates substantial quantities of residual mycelial biomass, much of which is discarded despite its potential as a source of value-added biopolymers. This study investigated the extraction of fungal chitosan from Pleurotus ostreatus mycelium waste...

Brian & Mayte Wedding Book

'Brian & Mayte Wedding Book,' by Brian Paul Kaess details the marriage photos/images of groom Brian Paul Kaess & bride Mayte urbina Pereda on their wedding day in Chicago. July 27, 2000.