Research works

Cardiac imaging biomarkers of heart failure in diabetes for phenotyping, risk stratification, and evaluating therapeutic response

Type 2 diabetes mellitus (T2DM) is a well-established risk factor for the development of heart failure (HF), yet HF risk within this population is highly heterogeneous. Appropriate biomarker selection and a limited mechanistic understanding of the phenotypic subtypes of HF in T2D...

Microstructural characterization, response surface modelling and multi-objective optimization of water hyacinth fibre-reinforced concrete

This study investigates the combined influence of water hyacinth fibre content (wt. % of cement) (0.5–2.0%) and fibre length (10–50 mm) on the water absorption (WA), density, and compressive strength (CS) of concrete using response surface modelling and multi-objective optimizati...

Robustness Analysis of Deepfake Detection under Platform-Specific Distortions: A Comparison of Spatial and Temporal Approaches

본 연구는 Stable Video Diffusion(SVD) 기반 딥페이크 영상의 탐지 성능이 실제 플랫폼의 왜곡 환경에서 어떻게 변화하는지를 분석하였다. 이를 위해 플랫폼별 왜곡 과정을 반영한 M-STAR 평가 파이프라인을 구축하고, 공간 기반(Xception, Swin Transformer-Tiny)과 시간 기반(R3D-18, VideoMAE) 탐...

Development and validation of a multifeature-integrated nomogram for predicting postoperative survival in macrotrabecular-massive hepatocellular carcinoma

Macrotrabecular-Massive Hepatocellular Carcinoma (MTM-HCC) represents a highly aggressive histologic subtype associated with a poor prognosis. This study aimed to construct and validate a Multifeature-Integrated Nomogram model based on clinical, pathological, and imaging characte...

Condition dependent variation in bioactive metabolites of Bacillus siamensis during interaction with fungal pathogens

Interactions between antagonistic bacteria and fungal pathogens influence extracellular metabolite production and contribute to the efficacy of antagonistic agents (AGAs). However, comprehensive characterization of condition dependent metabolite variation during bacterial-fungal...

Establishing MRI-based thresholds for corpus callosum in children aged 1–6: a comparison of typical development and cerebral palsy-associated morphometry

The corpus callosum (CC) is central to neurodevelopment, and morphometric abnormalities are linked to atypical development. This study aimed to establish age-dependent and age-independent MRI-based cutoffs defining normative CC morphology in children aged 1–6 years, distinguishin...

The Pediatric Hospitalist: A Survey of How We Are Doing

Physician well-being has important implications for clinicians, patients, and health care organizations. Burnout not only takes a human toll but is also associated with reduction in work hours, attrition, and medical errors.1 Conversely, career satisfaction is linked to improved...

MOSAIC: A Framework Integrating Molecular Structure and Chemical Knowledge Embeddings for Drug-Target Interaction Prediction

신약 개발 초기 단계에서 딥러닝을 활용한 약물–표적 상호작용 예측은 비용과 시간을 절감하는 핵심 과정이다. 하지만 기존 접근법들은 분자구조 정보에만 의존하여 생물학적 맥락을 놓치거나, 대안으로 도입된 지식 그래프는 구축 및 활용에서 비효율적이라는 한계를 가진다. 본 연구는 구조적 적합성...

Systemic immune-inflammation index, but not neutrophil-to-lymphocyte ratio, is a predictor for detecting clinically significant prostate cancer at first biopsy

To determine whether systemic immune-inflammation index (SIII) and neutrophil-to-lymphocyte ratio (NLR) could be predictive factors for detecting clinically significant prostate cancers at first biopsy in men with a PSA level of 3.0–10.0 ng/ml or abnormal digital rectal examinati...

Lightweight structure-aware detection of coal and gangue under complex operating conditions

Accurate coal-gangue detection under complex operating conditions is crucial for reliable online perception in underground coal handling. To address degraded imaging, dense stacking, adhesion, and occlusion, this study proposes a lightweight structure-aware detector, LCGA-YOLO11,...

RNA and lipid composition analyses reveal distinct profiles between HEK293-derived extracellular vesicles and HIV-1 Gag virus-like particles

Extracellular vesicles (EVs) and HIV-1 Gag virus-like particles (VLPs) represent promising platforms for therapeutic delivery and vaccine development. However, their molecular cargo may critically influence their biological properties and clinical applicability. In this study, a...

KDE-Based Statistical-Deep Learning Fusion V-MoE Model for Meat Taste Attribute Prediction under Data Scarcity

육류 품질 평가 분야에서 기존 등급 분류 기술은 98% 이상의 정확도를 달성한 반면, 육류 맛 속성 예측은 데이터 부족으로 미개척 영역으로 남아있다. 본 연구는 육류 단면 영상을 통한 맛 예측 딥러닝 모델을 개발하되, 소규모 한우 도축량으로 인한 학습데이터 부족 문제를 해결하고자 한다. 이를 위...

Elevated electrical stimulation thresholds for sciatic nerve block in individuals with diabetic complications: a systematic review and meta-analysis

Diabetes mellitus is associated with peripheral nerve structural alterations, potentially affecting nerve excitability. Electrical stimulation threshold is a key parameter for nerve localization during sciatic nerve block. This meta-analysis investigates the impact of diabetes me...

Effects of channels and decision justifications on perceptions of organizational listening

Extensive research on organizational listening has provided some general guidelines on how organizational listening should be conducted to address stakeholders’ concerns and needs. One of these guidelines relates to engaging with stakeholders on listening channels that they alrea...

SYK inhibitor fostamatinib promotes mitochondrial respiratory chain supercomplex formation and improves skeletal muscle function in aged mice

Mitochondria are major organelles involved in energy metabolism and play a crucial role in the function of muscular tissues. Mitochondrial respiratory chain (MRC) complexes are assembled to higher-order “MRC supercomplex (SC)” structures, which has been suggested to promote energ...

Tuning of generalized k-omega turbulence model for prediction of heat transfer and pressure drop for helium cooled demo FW

The HCPB blanket concept for EU-DEMO fusion reactors employs high-pressure (8 MPa) helium gas as coolant for the plasma facing first wall. Up-to-date estimations for the total maximum of heat flux go up to 0.73 MW/m². Higher short-term transient loads are possible. 60°-V-shaped r...

Nutritional status and dietary profile of people living with HIV/AIDS in three care sites of the Mbouda Health District, West Cameroon

HIV/AIDS pandemic remains a global crisis, particularly in Africa, with major consequences for public health and the economy. This study aimed to assess the nutritional status and dietary profile of People Living with HIV (PLHIV) in the Mbouda Health District with the objective o...

Simulation-based framework for early-stage assessment of building-integrated photovoltaics and battery storage in urban district master planning: Vienna case study

Dense urban districts require decision-support methods that allow architects and planners to evaluate renewable generation, storage and demand interactions while the master plan is still flexible. This paper presents a simulation-based workflow for early-stage assessment of build...

Strong Hotspot Domination Integrity of Corona Products, Comb Products and Shadow Graphs with Applications

The study of graph vulnerability parameters provides valuable insights into the structural stability and resilience of networks when there is a disruption. The strong hotspot domination integrity ( $$DI_{SH}$$ ) is one such measure, combining domination, integrity, and heatmap ce...

A rare and underrecognized complication of sickle cell disease in a pediatric patient: acute soft head syndrome

Acute soft head syndrome (ASHS) is an extremely rare and underrecognized complication of Sickle Cell Disease (SCD), and limited awareness can lead to misdiagnosis as infection or trauma. We report the case of a 16-year-old male with hemoglobin SS (HbSS) SCD who presented to the e...