Research works

Mucosal IgA to pre-fusion F protein predicts protection from RSV infection in a high burden setting

ABSTRACT Respiratory syncytial virus (RSV) causes over 100,000 annual deaths, predominantly in low-and middle-income countries, yet immunological correlates of protection remain poorly defined in high-burden settings. We conducted an intensively sampled prospective household coho...

Geodesic costs on a scalar field over the periodic table predict diatomic bond dissociation energies

Abstract We construct a scalar configuration field $$\Phi $$ on the periodic table lattice from z -score-normalized first ionization energy and covalent radius, with a single coupling parameter $$\lambda $$ fixed a priori . Geodesic costs computed on this field via Dijkstra’s alg...

Functional Evolution and Modular Behaviour in the Carnivoran Mandible

The relationship between form and function holds a central spot in evolutionary biology, as the changes in such relationship through time, are likely to deeply influence how organisms adapt to the surrounding environment. However, anatomical structures may be interpreted as a com...

Families of Two-Impulse Optimal Rendezvous Transfers Between Elliptic Orbits

Abstract The classical fuel-optimal two-impulse rendezvous problem between Keplerian orbits is revisited from a family-based perspective. Conventional approaches often yield isolated optimal solutions whose mutual relationships remain unclear; yet, when re-parameterized appropria...

Organic carbon pathways across the fluvial-marine transition zone of the Mackenzie River Delta – Beaufort Sea region and implications on ocean color remote sensing

Abstract. Arctic warming and hydrological intensification are accelerating permafrost thaw and increasing the export of terrestrial organic carbon (OC) and sediments from land via rivers and shallow coastal waters into marine waters, yet the fate of these materials in deltaic and...

Magma-induced midcrustal flow and high-temperature metamorphism: Insights from the early Mesozoic Yunkai massif (South China) and tectonic implications

The way in which partial melting weakens the middle continental crust and triggers lateral flow is fundamental to understanding orogenic processes, yet the specific roles of magmatic heat and deformation remain debated. We addressed this issue through an integrated study of the e...

ODIN: Confirmation and 3D Reconstruction of Six Massive Protoclusters at Cosmic Noon

Abstract Protoclusters represent sites of accelerated galaxy formation and extreme astrophysical activity characteristic of dense environments. Identifying massive protoclusters and mapping their spatial structures are therefore crucial for understanding how large-scale environme...

Numerical simulations of inorganic HTL-free perovskite Cs2PtI6 solar cell using SCAPS-1D

Abstract This study utilizes the SCAPS-1D to conduct a numerical simulation of lead-free solar cell device based on Cs 2 PtI 6 . We aim to explore the impact of eliminating hole transport materials (HTL) on the device's performance while ensuring high efficiency and stability. Th...

Transferable Optimization Network for Cross-Domain Image Reconstruction

Abstract. We develop a novel transfer learning framework to tackle the challenge of limited training data in image reconstruction problems. The proposed framework consists of two training steps, both of which are formed as bilevel optimizations. In the first step, we train a powe...

Development of a Photostable pH Biosensor Based on mStayGold

Fluorescent proteins (FPs) that are pH-sensitive play a crucial role in investigating pH-related cellular processes, such as endocytosis and exocytosis. Existing pH-sensitive FPs generated from Aequorea victoria green fluorescent protein (GFP), such as superecliptic pHluorin (SEP...

Outcomes of modified pneumatic retinopexy with transscleral subretinal fluid drainage for primary rhegmatogenous retinal detachment

Abstract Background Primary rhegmatogenous retinal detachment (RRD) occurs when a retinal tear or break causes fluid from inside the eye to seep behind the retina, which pushes it away from the wall of the eye. This can cause permanent vision loss if not treated. Which of three c...

OncoRAG: graph-based retrieval enabling clinical phenotyping from oncology notes using local mid-size language models

Abstract Oncology notes contain the richest clinical detail, yet they remain largely inaccessible at scale because extracting structured phenotypes requires either substantial language model infrastructure, curated training data, or cloud computing under regulatory constraints. W...

System-size dependence of charged-particle suppression in ultrarelativistic nucleus-nucleus collisions

High-energy partons lose energy while propagating through the hot, strongly interacting medium produced in ultrarelativistic nucleus-nucleus collisions, leading to a suppression of particle production at high transverse momentum (p(T)). The dependence of this energy loss on the s...

Multi-mode input–output model for cavity magnonics: Phase-resolved control of level repulsion, level attraction, and nonreciprocal transmission

We experimentally validate a unified input–output model that incorporates internal and external coupling phases across multiple cavity modes in a room-temperature cavity magnonic system. By explicitly accounting for both phase contributions, the model provides a clear interpretat...

Prospective validation of a non-invasive bedside protocol for tracheostomy decannulation in acquired brain injury with otolaryngologic concordance

Decannulation of tracheostomy in individuals with acquired brain injury (ABI) is challenging and often requires endoscopic airway assessment. A reliable noninvasive bedside protocol could support decision-making in neurorehabilitation settings. We conducted a prospective observat...

Health insurance in Nigeria: Findings from the People’s Voice Survey

Abstract The recent Lancet Commission on Nigeria’s health system highlighted high out of pocket expenditures on health and underfunding of the public health sector as major obstacles to Nigeria’s achievement of the Sustainable Development Goals. Nigeria has sought to address thes...

CAM-LDS: cyber attack manifestations for automatic interpretation of system logs and security alerts

Abstract Log data are essential for intrusion detection and forensic investigations. However, manual log analysis is tedious due to high data volumes, heterogeneous event formats, and unstructured messages. Although many automated log-analysis methods exist, they usually still re...

Separating Pause from Cancel? Evaluating the Pause-then-Cancel Model in Complex Stopping Tasks

This is a preprint for a commentary piece on a recent publication in the Journal of Neuroscience: Hervault, M., & Wessel., J. R. (2025). Common and unique neurophysiological processes that support the stopping and revising of actions. Journal of Neuroscience, 45(13). https://doi....

Cystinosin/Ers1 functions in redox homeostasis in the early secretory pathway

Abstract Cystinosis is an autosomal recessive inherited disorder caused by mutations in the CTNS gene, which encodes the highly conserved transmembrane protein cystinosin, a proton/cystine co-transporter at the lysosome membrane. However, reduction of cystine load in the lysosome...

Ecosystem-scale biogenic volatile organic compound fluxes over rapeseed by eddy-covariance

Abstract. Biogenic volatile organic compounds (BVOCs) are key precursors of ozone and secondary organic aerosols, yet their emissions from croplands remain poorly characterized. Here, we report what is, to our knowledge, the first ecosystem-scale quantification of BVOC fluxes ove...