Research works

Exploring the role of automated feedback in programming education: a systematic literature review

Automated feedback systems have become increasingly integral to programming education, where learners engage in iterative cycles of code construction, testing, and refinement. Despite its wider integration in practices and technical advancements into AI, research in this area rem...

Submerged Hazard Identification and Processing Using Augmented Image-Based Detection (SHIP-AID)

The identification of visible submerged hazards, including shallow-water shipwrecks and associated debris, is important for maritime safety, coastal management, environmental monitoring, and marine archeology. The scope is restricted to wrecks that remain optically visible from a...

Protein aggregation inhibitors induce divergent transcriptional responses in a cellular model of ɑ-synuclein seeded aggregation

Abstract Parkinson’s disease (PD), dementia with Lewy Bodies (DLB) and multiple system atrophy (MSA) are progressive neurodegenerative disorders marked by the pathological aggregation of alpha-synuclein (ɑSyn). Despite significant research efforts, effective therapeutic intervent...

The structure of the native cardiac crossbridge in the rigor state

Cardiac contraction is driven by double-headed myosin cycling on cardiac thin filaments, where troponin-tropomyosin regulates myosin access to actin. Prior research used a single-headed myosin bound to bare actin, thereby limiting insight into coordination between myosin heads an...

CAMS-REG-UNC-v8.1: a detailed uncertainty product for the gridded CAMS-REG-v8.1 emission inventory

Abstract. Independent verification of greenhouse gas emission reductions and trends in air pollution levels is receiving increasing attention. Atmospheric observations can provide such a constraint on emission estimates through inverse modelling, which requires a detailed quantif...

Prospective evaluation of high-risk assessment strategy for esophageal cancer: a community-based cancer screening cohort in rural China

Abstract Objective To evaluate a questionnaire-based strategy for risk stratification in population-based esophageal cancer(EC) screening in China. Methods 120,488 residents from four cancer screening centers in Shandong Province were enrolled in a prospective cohort between 2013...

Airborne measurements for investigating offshore wind farm wakes and modifications of sea state – benefits and limitations

Abstract. In the framework of the two large wind energy research projects WIPAFF and X-Wakes, crewed airborne measurements have been performed in and around wind farm clusters of the German Bight to investigate offshore wind farm wakes and associated sea-state modifications. Thes...

Between expertise and engagement: a qualitative study of Namibian geoscientists' views, attitudes, motivations, and objectives regarding public engagement with science

Abstract. Geoscientists are increasingly expected to engage with society on issues such as mining, groundwater management, energy transitions, and environmental sustainability, yet public engagement in the geosciences remains limited. This is largely due to reliance on one-way co...

Identifying heat-related diagnoses in emergency department visits among adults in Chicago: A heat-wide association study

Extreme heat is an escalating public health concern. Although prior studies have examined heat-health associations, their reliance on restricted diagnoses and diagnostic categories may miss or misclassify heat-related illness. Here, we conducted a heat-wide association study to e...

3D bulk-resolved g-wave altermagnetic order parameter in CrSb

Abstract Electronic phases of matter, such as magnetism and superconductivity, are defined and distinguished by their order parameters quantifying the spontaneous symmetry breaking underlying each phase. Simple cases include the uniform magnetization of ferromagnets 1,2 and the i...

The impacts of winter storms on sediment dynamics and shear front variability in the Yellow River Delta

Study region Yellow River Delta (YRD), China Study focus Delta evolution exhibits pronounced seasonal variability―seaward progradation in summer due to high sediment supply and weak ocean dynamics, versus winter retreat dominated by storm activity. However, winter storm impacts o...

Neonatal umbilical cord treatment: a prospective study on detachment time and complications with different topical approaches

Abstract Background Umbilical granuloma (UG) is a common neonatal condition resulting from excessive granulation tissue at the umbilical stump, often leading to prolonged secretion and minor bleeding. While silver nitrate cauterization remains the standard treatment, there is gro...

Amplicon-based long-read sequencing for accurate CYP2D6 gene deletion and duplication detection using CYP2D7 as a reference gene

Abstract We developed an amplicon-based long-read sequencing approach that enables simultaneous detection of CYP2D6 single-nucleotide variants (SNVs) and copy-number variations (CNVs) in a single reaction. The SNVs of the two pseudogenes, CYP2D7 and CYP2D8, were also comprehensiv...

Engineering antigenic breadth against SARS-CoV-2 by pairing divergent RBDs within a single mRNA immunogen

Abstract Vaccines capable of eliciting broadly neutralising antibodies (bnAbs) are a major goal for pandemic preparedness. A persistent challenge across vaccine Wields is how to deliberately recruit the rare B cell clones that recognise conserved epitopes shared across diverse vi...

Using street view images and visual LLMs to predict heritage values for governance support: risks, ethics, and policy implications

Abstract Until 2026, the Energy Performance of Buildings Directive is implemented in the European Union member states, requiring all member states to have National Building Renovation Plans. In Sweden, there is no comprehensive national register of buildings with heritage values....

lncRNAs contribute to caste differentiation as a regulatory layer in ants

Abstract Caste differentiation in ants represents one of the major evolutionary transitions and provides a unique model for studying developmental mechanisms underlying division of labor. Genetically identical individuals follow divergent epigenetically-regulated developmental tr...

Study on land-use change (LUC)-induced carbon emissions

Land-use change (LUC)-induced carbon emissions ( E LUC ), defined as net carbon emissions and removals, have accounted for approximately one-third of global anthropogenic carbon emissions since industrialization. The complex temporal evolution of annual E LUC observed globally an...

A quadratic-scaling algorithm with guaranteed convergence for quantum coupled-channel calculations

Rigorous quantum dynamics calculations provide essential insights into complex scattering phenomena across atomic and molecular physics, chemical reaction dynamics, and astrochemistry. However, the application of the gold-standard quantum coupled-channel (CC) method has been fund...

Anti-collinear resummation in JIMWLK evolution in the linear regime

A bstract The recently-proposed resummation procedure for anti-collinear logarithms in the JIMWLK kernel [1] is studied in the linear (BFKL) regime in the fixed-coupling approximation. Simple closed form expressions for the resummed momentum space kernel and characteristic functi...

ReMeDy : A Flexible Statistical Framework for Region‐Based Detection of DNA Methylation Dysregulation

Region-based epigenome-wide association studies have demonstrated improved statistical power and biological interpretability compared with probe-wise analyses of DNA methylation data. However, most existing region-based methods characterize methylation dysregulation primarily thr...