Research works

EditQL: A query language for evolving models

Abstract Context: Technically sophisticated systems are the result of the joint work of several domain experts. However, the more people collaborate, the more important it becomes to make the model evolution and its single edit operations accessible and comprehensible for involve...

Metabolic control of smooth muscle cell phenotype switching in atherosclerosis

Abstract The loss of smooth muscle cell (SMC) contractile phenotype contributes to various diseases including atherosclerosis. However, its metabolic basis is not entirely elucidated. Since the transforming growth factor beta (TGFβ) signaling is among principal regulators of SMC...

Spontaneous segmentation of slow slip events on a homogeneous planar fault

Abstract Slow slip events (SSEs) are transient aseismic fault slip events that often display segmentation along strike. While fault segmentation is commonly attributed to physical heterogeneities, numerical studies have shown that segmentation can also occur on homogeneous planar...

Prefoldin function links meiotic chromosome segregation with cellular remodeling and reveals tubulin sensitivity of the meiotic spindle

Abstract Faithful chromosome segregation is essential for producing viable gametes during meiosis, a specialized type of cell division compared to mitosis. Unlike mitosis, meiosis involves two consecutive chromosome segregation events without an intervening round of DNA replicati...

A sustainability index for strategic mine planning: integrating closure and environmental costs into phase prioritization

Abstract This paper proposes a phase-based evaluation workflow for strategic mine planning in which environmental and closure costs associated with each project phase are quantified after a base-case block sequencing and then compared with the economic performance of the resultin...

A Scoping Review of Virtual Reality in Blue Space Research

This study aims to systematically review the current applications and development trends of virtual reality (VR) technology in blue space research. It clarifies the main research methods, technical pathways, application scenarios, and existing knowledge gaps, and integrates the a...

Parental niche construction buffers microbial and competitive challenges and drives offspring dependence in burying beetles

Parents across diverse taxa modify the biotic or abiotic environments of their offspring. Such modifications may constitute ecological inheritance and are central to developmental niche construction, whereby organisms shape developmental conditions and selective pressures experie...

An efficient cross-chain interaction mechanism for large-scale multichain environments

Abstract To address the scheduling difficulties, high verification overhead, and insufficient transaction processing efficiency encountered in cross-chain interactions under high-concurrency scenarios, an efficient cross-chain interaction mechanism is proposed. First, a cross-cha...

Data-driven styling optimization of an intelligent medical waste recycling robot using AHP-CRITIC and SSA-ELM

Abstract To improve the attractiveness and practicality of intelligent medical waste recycling robots, this study proposes a data-driven styling optimization framework integrating Kansei Engineering, AHP-CRITIC weighting, and a Sparrow Search Algorithm-optimized Extreme Learning...

Crimean-Congo hemorrhagic fever virus protein GP38 from isolate M18-China confers broad immunological breadth

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne, negative-strand RNA virus that causes outbreaks of lethal hemorrhagic fever. No approved vaccines or specific antiviral treatments are available. CCHFV glycoprotein GP38 is an integral component of the pre-fusion glyc...

Expert Consensus Develops Multidisciplinary Pathway for Cancer Pain Management in Italy: A Delphi Study

Background: Cancer pain remains highly prevalent and undertreated despite established guidelines. In Italy, Law 38/2010 mandates systematic pain assessment, yet only 26% of clinicians routinely evaluate pain at each clinical visit, and fewer than one-quarter have received formal...

A Systematic Transparency Assessment Framework for Life Cycle Background Database to Address Three-Level Black Boxes

Life cycle background database (LCBD) is central to carbon footprint and life cycle assessment (LCA) modeling, yet transparency remains inconsistent across mainstream (ecoinvent, GaBi, USLCI) and emerging (TianGong, HiQLCD) databases. A lack of unified disclosure standards result...

POLIS V13: A Universal Tensional Conservation Theory – Unification of Matter, Energy, Information, Gravity, Light, Life, Consciousness and Cosmology

POLIS V13 is the complete formulation of the tensional conservation framework, generalising V12 while preserving all its empirical validations. The theory replaces fixed physical analogies (solid, liquid, gaseous) with neutral tensional layers identified solely by their normalise...

Mercury–carbon relationships in environmental media near artisanal gold mining sites in Guyana

Elevated atmospheric mercury (Hg) concentrations from artisanal gold mining increase Hg exposure in adjacent forest canopies. Although pools and fluxes of Hg and carbon (C) within environmental media are connected, it is unclear how these Hg/C patterns may differ between areas ex...

Responsible artificial intelligence in Indonesian undergraduate AI curricula based on a national document analysis

The rapid expansion of undergraduate artificial intelligence (AI) programmes has created an educational challenge. Graduates need strong technical preparation, and they must also be able to design and evaluate AI systems responsibly. This study examines how responsible AI and hum...

Ocean Literacy and Blue Entrepreneurship in Vocational Education: A Systematic Bibliometric and Network Science Analysis

Background The transformation of the global marine economy towards a blue economy requires a workforce integrating marine literacy, technical competence, and entrepreneurial capacity. Although ocean literacy research has developed rapidly in general education, its engagement with...

Parafermionizing the monster

A bstract We study the parafermionization of the Monster CFT with respect to its ℤ pA subgroups, with p an odd prime. Under certain assumptions, we show that the parafermionization is equal to a non-invertible gauging of $$ \mathcal{P}(p)\times \mathcal{P}{(p)}^{\vee } $$ P p × P...

Digital literacy and academic performance in visual arts teacher education in Ghana

Abstract Despite growing evidence that digital literacy supports student learning, little is known about its relationship to perceived academic performance among pre-service visual arts teachers, particularly within teacher education in Ghana. Grounded in Connectivism and Social...

Comprehensive exploration of the C3H8N radicals potential energy surface

C3 amines (C3H9N) are the simplest aliphatic amine subgroup encompassing primary, secondary, and tertiary isomers, playing a key role in understanding nitrogen migration during biomass thermal conversion. Despite extensive computational studies on the H abstraction rates of C3 am...

Electric double layer engineering via salt additives for enhanced OER under weakly acidic conditions

The oxygen evolution reaction (OER) is the kinetic bottleneck in water electrolysis, particularly in acidic electrolytes. High-performance electrolyzers rely on strongly acidic conditions, which severely corrode cell components and increase system costs. To mitigate this issue, a...