Research works

Facilitating advance care planning in oncology: study protocol for the evaluation of a tailored implementation of an advance care planning tool (the INDEED study)

Abstract Background Advance care planning (ACP) improves patient outcomes, but integration of ACP in daily practice for patients with cancer in hospitals remains suboptimal. Systematic implementation of tools to facilitate ACP could overcome the barriers for ACP. In this study we...

Bayesian Nonlinear Structural Model Parameter Updating Using Visual Damage Indicators

Abstract Postearthquake decisions regarding the repair, retrofit, and safety of damaged infrastructure often rely on accurate estimates of structural response demands. These estimates are highly sensitive to uncertain material parameters whose true values often deviate from those...

Solvent-Free Bubbling Extraction Mass Spectrometryfor Ultrasensitive, Size-Independent Detection of Microplastics inWater

Abstract Ultratrace microplastics (MPs) in aquatic environments are a growing problem for ecosystems and human health, yet their reliable detection at subng/L levels with sub-100 nm particle sizes remains a substantial analytical challenge. Herein, we introduce a solvent-free and...

The effect of health behaviour interventions on alcohol consumption among people living with cancer: a systematic review

PURPOSE: This systematic review synthesises data relating to the effectiveness of behavioural interventions aimed at reducing alcohol consumption among people living with cancer. METHODS: Five databases were systematically searched for randomised controlled trials (RCTs) publishe...

Medication transitions and predictors of illicit substance use during opioid agonist treatment: a three-year follow-up study

Abstract Background For opioid use disorder (OUD), pharmacological therapy using methadone or buprenorphine, plus psychosocial support, is the most effective opioid agonist treatment (OAT). Long-acting injectable buprenorphine (LAIB) is the newest buprenorphine formulation. This...

Spatial Regulation of Preameloblast Development in Response to Distal Mouse Incisor Injury

Enamel, the outermost mineralized tissue of the tooth, is produced by specialized dental epithelial cells called ameloblasts. Unlike human enamel, which lacks regenerative capacity, the mouse incisor grows throughout life, driven by adult stem cells residing in the labial cervica...

Physics-aligned causal inference of driving styles on electric vehicles battery aging

Abstract Lithium-ion batteries (LIBs) remain the core service life bottleneck of electric vehicles (EVs), and driving style is a critical human factor dominating EV battery degradation as assessed via aging proxy indicators and semi-empirical model predictions. Existing studies m...

Strict Total Positivity of Order Four for the de Bruijn--Newman Kernel

We prove that the de Bruijn--Newman kernel associated with the Riemann Xi function is strictly totally positive of order four. Let \[K(x,y)=\Phi(x-y),\] where \(\Phi\) is the classical positive even Riemann kernel. We establish that for every \[1\le m\le4,\] and every pair of str...

The Open-Data Appendix (The Receipts Ledger)

This open-data appendix compiles the raw empirical receipts and comprehensive interaction logs verifying Case Study 6 of 6. Serving as the primary data ledger for a live public discourse audit (N = 214), this document archives the exact textual outputs generated by digital forum...

Associations between organizational readiness and implementation fidelity in national implementation of WHO’s labour care guide in Sweden: a prospective observational study

Abstract Background During 2024 and 2025, an adapted version of the World Health Organization’s Labour Care Guide was implemented in approximately half of Sweden’s labor wards within the PICRINO trial. Organizational readiness is widely regarded as a key determinant of successful...

Securing Digital Transformation: Lessons from the February 2024 Ransomware Attack on Malawi's Immigration Service

Malawi's public sector is digitizing rapidly to improve services, yet most departments lack basic cybersecurity foundations to protect sensitive data. Immigration systems hold highly confidential citizen and traveler records, making them prime targets where phishing, ransomware,...

Patient selection for PRRT rechallenge in neuroendocrine tumors: impact of initial response duration on outcomes

BACKGROUND: Patient selection for rechallenge peptide receptor radionuclide therapy (re-PRRT) in neuroendocrine tumors (NET) remains poorly defined. As re-PRRT is increasingly considered in clinical practice, identifying patients most likely to benefit has become a critical yet u...

Sustainable Recovery of Platinum Group Metals via Oxysalt Phase Reconstruction and Subsequent Deep Eutectic Solvent Leaching

Abstract The recycling of platinum group metals (PGMs) underpins sustainable development across semiconductors, new energy devices, and catalytic materials. Efficiently enriching and extracting these sparsely distributed PGMs from solid wastes such as spent catalysts still pose a...

Enhanced Antibiotics Sieving by Exfoliated TiS2 Membranes via Surface Functionalization and Passivation

Abstract Transition metal dichalcogenide (TMD) nanolaminate membranes hold great promise for molecular sieving due to their two-dimensional capillary structures, which facilitate size-restricted diffusion. However, many transition metal sulfides exhibit intrinsic instability and...

Transforming heterogeneous fibreboard waste into form-pressed bio-polyester composites

Abstract Efficient recycling of fibreboard production residues is hindered by their chemical heterogeneity, fine particle size and low bulk density, which limit transport and reprocessing in conventional processing routes. This study investigates the transformation of heterogeneo...

Delayed vasocutaneous fistula following vasectomy associated with retained silk ligature: a case report with clinicopathological correlation

Abstract Background Vasectomy is a safe and highly effective method of permanent male contraception. Delayed vasocutaneous fistula is an exceptionally uncommon complication, and its diagnosis requires careful correlation of clinical, laboratory, operative and pathological finding...

Cofactor-Free Tau FilamentsAre Dynamic and UndergoStructural Evolution Driven by Thermodynamic Control

Abstract Tau filaments are a hallmark of neurodegenerative tauopathies, such as Alzheimer’s disease (AD). Structural studies have revealed that patient-derived tau fibrils adopt distinct folds in different tauopathies; however, it is unclear what forces guide this process. To exp...

Constructing multifunctional biointerfaces: Polyoxometalate-based hydrogels—design, functionalization, and translational challenges

Abstract Polyoxometalate (POM)-based hydrogels are emerging organic-inorganic hybrid materials that combine the biological functions of POMs with the biocompatibility and tunable mechanical properties of polymer networks. This review summarizes recent advances in their compositio...

Early warning and advisory can contribute to enhanced wheat stem and yellow rust management in Ethiopia

Abstract Wheat rusts are major constraints for global wheat production, leading to substantial yield and economic losses. To mitigate rust related production risks, disease forecast models generate time and location-specific information on the emergence and spread of wheat rusts....

Carbon Quantum Dot-Modifiedg-C3N5 and g-C3N4 Nanocompositesfor Sunlight-Driven Wastewater Remediation

Abstract Carbon quantum dot (CQD)-modified carbon nitride nanocomposites have emerged as promising sunlight photocatalysts for wastewater remediation owing to their tunable electronic structures and efficient charge-transfer properties. Herein, CQD-modified g-C3N4 (N4Q) and g-C3N...