Research works

Searching the Druggable Genome using Large Language Models

Summary: The druggable genome encompasses the genes that are known or predicted to interact with drugs. The Drug-Gene Interaction Database (DGIdb) provides an integrated resource for discovering and contextualizing these interactions, supporting a broad range of research and clin...

Interval Scheduling Games with Color-Based Concurrent Jobs

We consider a game theoretic variant of an interval scheduling problem. Every job is associated with a length, a weight, and a color. Each player controls all the jobs of a specific color, and needs to decide on a processing interval for each of its jobs. Jobs of the same color c...

Spliceosome gene mutations synergize with anthracyclines to amplify atrial fibrillation risk in hematologic malignancies: a multicenter cohort study with discovery and validation

Abstract Background Atrial fibrillation (AF) is a life‑threatening complication in patients with hematologic malignancies, yet personalized risk stratification remains challenging. Spliceosome gene mutations are key drivers of these malignancies, but their specific role in AF pat...

4CzIPN Photosensitizes the Cobaloxime‐Catalyzed Light‐Driven Hydrogen Evolution Reaction

TADF compounds have found great application as photocatalyst in recent years. Their use as photosensitizers (PS), however, is still limited although they have a huge potential as abundant alternatives for traditional noble metal-based PSs, such as [Ru(bpy)3]2+. We herein investig...

Low-light image enhancement with retinex theory optimized by improved whale optimization algorithm

Abstract To solve the problems of insufficient contrast, blurred details, and color distortion in low-light image Enhancement, this paper proposes a Low-Light Image Enhancement with Retinex Theory Optimized by Improved Whale Optimization Algorithm(WOA). The method innovatively em...

Photons Do Not Fly. Nonlocal Theory of Relativity. Impulse Theory of Interaction.

This work presents a foundational reformulation of field interactions, introducing the Impulse Theory of Interaction. The theory challenges the standard paradigm by positing that what is conventionally described as continuous fields is the statistical manifestation of discrete, n...

Toward Explaining Large Language Models in Software Engineering Tasks

Recent progress in Large Language Models (LLMs) has substantially advanced the automation of software engineering (SE) tasks, enabling complex activities such as code generation and code summarization. However, the black-box nature of LLMs remains a major barrier to their adoptio...

Research on analytic hierarchy process for environmental risk assessment and source control during power grid construction stage

Comprehensive assessment of environmental risks associated with power grid enterprises is performed in this paper, which provides fundamental support for safety source management practices and the improvement of enterprise safety production systems. The Analytic Hierarchy Process...

Materium: An autoregressive approach for material generation

We present Materium: an autoregressive transformer for crystal-structure token sequences. These sequences include elements with oxidation states, fractional coordinates and lattice parameters. Unlike diffusion approaches, which refine atomic positions iteratively through many den...

Recreational Substance Use is Linked to Deficits in Recall, but Not Recognition Memory

This study assessed various memory processes (i.e., free recall, cued recall, item recognition, and source recognition) in individuals with and without a history of recreational substance use to identify which aspects of memory are more vulnerable to substance use.The sample cons...

Complete strategy spaces reveal hidden pathways to cooperation

Understanding how cooperation emerges and persists is a central challenge in evolutionary game theory. However, models of communication often rely on restricted strategy sets, making it unclear whether omitted behaviours alter cooperation. Here, we study the complete deterministi...

The DGA of planar loops when 2n=4

Abstract The DGA of planar loops is a pictorial chain complex introduced in a recent paper of the author, Boyd, Randal‐Williams and Sroka, where a minimal model for it was given. In the first non‐trivial case, , we give a new model which incorporates two natural ‘reflection’ invo...

RescueLens: LLM‐powered triage and action on volunteer feedback for food rescue

Abstract Food rescue organizations simultaneously tackle food insecurity and waste by working with volunteers to redistribute food from donors who have excess to recipients who need it. Volunteer feedback allows food rescue organizations to identify issues early and ensure volunt...

Coordinated Nonlinear Model Predictive Control for a distributed thermoelectric-based battery thermal management system

Electric vehicles (EVs) rely on lithium-ion batteries that require sophisticated battery thermal management systems (BTMS) to maintain safety, performance, and longevity. A critical challenge is mitigating cell-to-cell temperature variations, which accelerate non-uniform ageing a...

Using wavelet domain fingerprints to improve source camera identification

Camera fingerprint detection plays a crucial role in source identification and image forensics, with wavelet denoising approaches proving to be particularly effective in extracting sensor pattern noise (SPN). In this article, we propose a modification to wavelet-based SPN extract...

Quantum quenches from the critical point: theory and experimental validation in a trapped-ion quantum simulator

Abstract We investigate quantum quenches starting from a critical point and experimentally probe the associated defect statistics using a trapped-ion quantum simulator of the transverse-field Ising model. The cumulants of the defect number distribution exhibit universal scaling w...

Dynamic modulation of long-range photon-magnon coupling

Abstract Evidence of non-Hermitian behaviour has been recently demonstrated in cavity magnonics, including the emergence of mode level attraction and exceptional points in spectroscopic measurements. This work demonstrates experimental evidence of time-domain dynamics of magnon-p...

Strategies to optimize antimicrobial use and control antimicrobial resistance: an evidence-informed policy process

Abstract Background Antimicrobial resistance (AMR) is a public health priority in Colombia and worldwide, with implications for human, animal, and environmental health. This study presents an evidence-informed policy process designed to support the Colombian Ministry of Health (C...

A Survey on Centrality and Importance Measures in Hypergraphs: Categorization and Empirical Insights

Identifying central entities and interactions is a fundamental problem in network science. While well-studied for graphs (pairwise relations), many biological and social systems exhibit higher-order interactions best modeled by hypergraphs. This has led to a proliferation of spec...

Does scientific writing converge to U.S. english? evidence from generative AI-assisted publications

Abstract A growing literature documents that generative artificial intelligence (GenAI) is changing scientific writing. Much of this literature, however, focuses on absolute changes in vocabulary or readability. An important question remains unanswered: Does GenAI use lead to sys...