Neuroscience · Cognitive Neuroscience
In a community-based study of 2,007 older Korean adults, suicide attempts showed relatively high scores for connecting different depressive symptoms and for being explained by neighboring symptoms. The finding was not consistent across all measures, and women’s symptom networks appeared denser around suicide-related symptoms.
A systematic review of 86 studies found that artificial intelligence systems using brain MRI can distinguish people with autism from comparison groups in research settings. But reported accuracy varies substantially with the data and testing design, and the evidence is not yet strong enough for routine clinical use.
Researchers created a high-resolution map of genetic regulation in the human prefrontal cortex using 5.6 million nuclei from 1,384 donors. The atlas revealed cell-specific regulation of genes linked to brain disorders that bulk-tissue studies had not detected.
A whole-brain model of 90 anatomically connected regions produced a wider range of activity patterns when each region included interacting excitatory and inhibitory cell populations. The researchers also found that the brain’s modeled wiring helped produce fast gamma rhythms whose amplitude changed with slower rhythms.
Researchers found that information flow between major brain networks differed between autistic participants and non-autistic controls. An artificial-intelligence system classified the two groups with a mean accuracy of 91% across cross-validation, but the study does not establish a clinical biomarker.
