Yonsei University

Comparison of stool DNA–based SDC2 methylation testing and repeat fit for advanced colorectal neoplasia in fit-positive individuals: a multicenter prospective exploratory study

Abstract Background and Aim Fecal immunochemical test (FIT)–based colorectal cancer (CRC) screening is limited by false-negatives due to bleeding dependence and a high false-positive burden. We compared the diagnostic accuracy of stool DNA–based SDC2 methylation testing versus re...

Residential indoor air monitoring to assess long-term exposure to air pollution in susceptible populations for epidemiology: overview and early findings

While there has been accumulating evidence of the association between long-term exposure to air pollution and various health endpoints, most epidemiological studies relied on ambient air pollution which showed substantial deviation from indoor. This difference could lead to biase...

Synthetic data-driven framework for estimating worker activity intensity using pose-based graph neural networks

This paper proposes a metabolic equivalent of task (MET) class prediction framework that combines Stable Diffusion-generated synthetic images with B-ResSkelGCN, which learns from skeleton graphs, for non-contact evaluation of construction workers' workload levels. Using domain-in...

Delayed diagnosis and brain biopsy in central nervous system intravascular large B-cell lymphoma: a three-patient case series

Central nervous system intravascular large B-cell lymphoma (CNS IVLBCL) is a rare, aggressive lymphoma that can mimic inflammatory, infectious, demyelinating, and vascular disorders.We describe three patients with pathologically confirmed CNS IVLBCL who presented with progressive...

Timepoint-Specific Percentile Reference Curves for C-Reactive Protein and Erythrocyte Sedimentation Rate After Uncomplicated Primary Reverse Shoulder Arthroplasty: A Single-Center Cohort Study

Background/Objectives: No shoulder-specific percentile reference range exists for postoperative C-reactive protein (CRP) or erythrocyte sedimentation rate (ESR) after reverse shoulder arthroplasty (RSA); clinicians rely on time-invariant thresholds borrowed from lower-extremity c...

Structured Conducting Polymers Templated from Ouzo-Induced Oxidant Superstructures for High-Performance Supercapacitors

Conducting polymers (CPs) that are structured in very specific shapes have been successfully synthesized via vapor phase chemical oxidative polymerization of monomers with oxidant superstructures as templates. A ternary mixture of iron(III) p-toluenesulfonate hexahydrate (Fe(pts)...

Ferritin Complex Vaccine against Influenza A Using Screened Immunogenic Sequences from Fv-Antibody Library

Abstract A ferritin-based influenza A vaccine was developed. The immunogenic sequences of the nucleoprotein (NP) were screened using an autodisplayed Fv-antibody library, and the paratopes with a high-affinity binding affinity were analyzed through docking simulations. The result...

A refined MASH–HCC model identifies macrophage Gadd45b as a key orchestrator of inflammation-driven neoplastic progression

Abstract Metabolic dysfunction-associated steatohepatitis (MASH) is emerging as a leading driver of hepatocellular carcinoma (HCC), yet the molecular mechanisms linking metabolic stress, chronic inflammation and tumorigenesis remain poorly understood. Here we established a metabo...

Factors influencing patient satisfaction in adult thoracolumbar deformity surgery: a single-center retrospective study

Objective: This study aimed to identify demographic and radiographic factors associated with patient satisfaction after adult thoracolumbar deformity surgery using a single-center retrospective database.Methods: Data were collected from 2014 to 2021.Of 359 patients screened, 107...

Beyond the algorithm: what makes artificial intelligence-assisted colonoscopy effective in routine practice?

Effectiveness of a novel artificial intelligence-assisted colonoscopy system for adenoma detection: a prospective, propensity score-matched, non-randomized controlled study in Korea ENAD-assisted colonoscopy significantly improved the ADR, APC, and SSLDR in real-world clinical pr...

Dopant-Level Cobalt as an Electronic Promoter Stabilizes NiOOH for the Efficient Electrochemical Oxidation of 5-Hydroxymethylfurfural (HMF) to 2,5-Furandicarboxylic Acid (FDCA)

Abstract The electrochemical oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA) is a promising route to biobased polymers using Ni-based hydroxide anodes. Although Co incorporation enhances performance, its mechanistic role in HMF oxidation remains un...

Short‐Term Changes in the Occlusal Contacts During Anterior Segmental Orthodontic Treatment With Clear Aligners in Adult Patients

ABSTRACT Objective To compare ClinCheck‐predicted and achieved maxillary occlusal contact areas immediately after an initial 14‐aligner anterior segmental sequence without programmed posterior movement. Materials and Methods This retrospective study included 31 adult women treate...

Noninvasive surrogate endpoints in MASH trials: current perspectives and challenges

Abstract Background Metabolic dysfunction-associated steatohepatitis (MASH) is a leading cause of cirrhosis and liver-related morbidity. Current regulatory pathways rely on histology and long-term clinical outcomes, but repeated liver biopsy is noninvasive and poorly reproducible...

Deep learning–based automated cervical length measurement improves spontaneous preterm birth risk stratification in women with a borderline short cervix (20–25 mm) at mid‐trimester: A retrospective cohort study

Abstract Objective This study evaluates whether deep learning (DL)‐based automated cervical length (CL) measurement provides improved risk stratification for spontaneous preterm birth (PTB), compared with conventional CL measurement methods, in women with a borderline short cervi...

Electrolyte Lubricants for Solid-State Batteries

Abstract Solid-state batteries (SSBs) promise higher energy density and improved safety, but interparticle voids and unstable solid–solid interfaces still limit their performance. Here, we translate the concept of lubrication into an electrolyte-lubrication strategy for SSBs. We...

Decoupling the Retention–Energy Trade‐Off Through Structural Reorganization of Synaptic Polyelectrolytes for Nonvolatile Neuromorphic Devices

ABSTRACT Electrolyte‐gated synaptic transistors (EGSTs) are promising ion‐mediated artificial synapses, but their performance is constrained by a retention–energy trade‐off. Enhancing long‐term memory (LTM) retention often requires enhanced ion accessibility, which can induce exc...

Optimal gating envelope size for automatic gating in magnetic resonance imaging–guided radiotherapy

Purpose This study aimed to investigate the optimal gating envelope (GE) size for automatic gating in magnetic resonance imaging–guided radiotherapy (MRIgRT) for liver cancer. Methods This study retrospectively analyzed imaging and radiation treatment data from ten patients with...

Tear-Based Dynamic Network Biomarkers for Pre-Disease Detection of Hyperuricemic Nephropathy via Smart Contact Lens

Abstract Early identification of the pre-disease state is critical for effective intervention and improved outcomes in chronic kidney disease. However, current diagnostic approaches mainly rely on serum-based biomarkers, which are limited in capturing dynamic physiological change...

Multifunctional Matrix‐Activated Electrodes Enabling Efficient Proton Transport and Durable Low‐Pt Operation for High‐Temperature Proton Exchange Membrane Fuel Cells

ABSTRACT Phosphoric acid (PA)‐related challenges, including PA loss, redistribution, and flooding, critically limit the performance and long‐term durability of high‐temperature proton exchange membrane fuel cells (HT‐PEMFCs) based on PA‐doped membrane electrode assemblies. Althou...

Association of Placental Tissue S100A14 Expression with Histologic Chorioamnionitis in Preterm Birth

Background/Objectives: S100A14 has been implicated in cellular signaling and tissue remodeling, but its relationship with histologic chorioamnionitis (HCA) remains unknown. We evaluated its placental expression and discriminatory performance for HCA in preterm birth. Methods: Thi...