University of Milan

The Orbitofrontal Expansion for Extending Nasoseptal Flap Reach in the Frontal Sinus

Abstract Skull base defects involving the superior and lateral posterior table of the frontal sinus are challenging to reconstruct due to limited surgical access and restricted reach of available reconstructive options. External approaches are often required, increasing morbidity...

Cholesterol nose-to-brain delivery as a possible therapeutic strategy in Huntington’s disease

Abstract Background Huntington’s disease (HD) is a genetically dominant neurodegenerative disorder characterized by several pathological mechanisms, including the disruption of brain cholesterol homeostasis. In several HD animal models, brain cholesterol biosynthesis and levels a...

Fiberoptic endoscopic evaluation of swallowing in neurogenic oropharyngeal dysphagia in adults: Part 2 of a scoping review

PURPOSE: The main objective of this scoping review was to describe the qualitative and quantitative parameters of fiberoptic endoscopic evaluation of swallowing (FEES) protocols, including their operational definitions and scales used in adults with neurogenic oropharyngeal dysph...

Iron oral supplementation in anemic patients undergoing orthopedic prosthetic surgery: a randomised trial comparing short_term and prolonged administration regimen

Preoperative anaemia in patients undergoing major elective orthopaedic surgery is a relatively frequent condition and is associated with perioperative transfusions. The aim of the present study was to investigate the efficacy of liposomal iron, folic acid, and vitamins in reducin...

Microfragmented Adipose Tissue in Pain Management: Bridging Regenerative Biology and Clinical Therapeutics

Regenerative medicine has emerged as a transformative paradigm in contemporary healthcare, shifting the therapeutic focus from symptomatic management toward the restoration of tissue structure and function through biologically active interventions. Within this framework, adipose-...

Exploring Sustainability Reporting in the Fashion Industry Towards European Sustainability Reporting Standards: Evidence on ESRS Readiness

ABSTRACT In recent years, companies have increasingly sought to strengthen their sustainability commitment and reporting practices, particularly in industries with significant environmental and social impacts, such as fashion. The completeness and quality of sustainability report...

Collective Risk Measures for Processes

Abstract This paper develops a comprehensive framework for collective risk measures, tools designed to quantify the aggregate risk stemming from a collective of agents. Crucially, these measures explicitly account for inter-agent cooperation, allowing agents to exchange risk thro...

Comparisons of Novel Risk Stratification Models to the Current cT1a/b Staging in Incidental Prostate Cancer

OBJECTIVE: Incidental prostate cancer (PCa) patients are currently stratified to either cT1a vs. cT1b stage, depending on tumor volume (< 5% vs. > 5%) in the resected tissue. We tested for other models that could improve cancer-specific survival (CSS) predictions. METHODS: Incide...