University of Michigan

A \({(2+\varepsilon )}\)-Approximation Algorithm for Metric \({k}\)-Median

Abstract. In the classical NP-hard (metric) [Formula: see text]-median problem, we are given a set of [Formula: see text] clients and centers with metric distances between them, along with an integer parameter [Formula: see text]. The objective is to select a subset of [Formula:...

Public Access, Open Access, and the Need for NIH Governance

This Viewpoint discusses the confusion between public access and open access, pay-to-comply publisher practices, and the steps that the National Institutes of Health (NIH) must take to fill this gap and promote public access goals.

Driving anger reduces the evasive response likelihood in near-crash events: Insights from SHRP 2 Naturalistic Driving Study

Introduction: Anger is a prevalent emotion that has been shown to negatively impact driving behavior, contributing to aggressive driving and road rage—both of which are well-known threats to traffic safety. This study investigated the effects of driving anger on evasive maneuvers...

Structural determinants of quadriceps atrophy following ACL injury: Evidence for fibre atrophy without fibre loss or overt peripheral denervation

Quadriceps atrophy is a well-established consequence of anterior cruciate ligament (ACL) injury, yet the mechanisms driving this process remain poorly characterized. Specifically, it is unclear whether atrophy reflects decreases in fibre cross-sectional area (CSA) or fibre number...

P1.188. Correlation Between ICG Fluorescence Angiography Kinetics and Tissue Oxygen Saturation Gradients During Gastric Conduit Perfusion Assessment

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background Poor gastric conduit perfusion is associated with post-esophagectomy anastomotic leak. Oxygen saturation imaging (OSI) can be used to demonstrate a snapshot assessment of perfusion as an alternat...

Prediagnostic circulating 25-hydroxyvitamin D and prostate cancer-specific survival: a collaborative pooled analysis of 13 prospective studies

Abstract Background Previous research suggests higher risk of prostate cancer diagnosis in men with high vitamin D serology, but there are limited data related to prostate cancer survival. In this study, we examine the associations between prediagnostic circulating levels of 25-h...

Acute Exposure to Perfluorooctanoic Acid (PFOA) During Cardiomyogenesis disrupts Transcriptional and Electrophysiological Profiles in Differentiated Myocytes

Abstract Exposure to per and polyfluoroalkyl substances (PFAS) are linked to various cardiovascular diseases (CVDs), but effects of developmental PFAS exposures on the human heart remain unclear. Using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM), the obj...

P1.227. A Composite Body Composition Score Independently Predicts Long-Term Survival After Esophagectomy for Cancer

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – long term outcomes Background Body composition (BC) measures are established determinants of esophageal cancer outcomes. Beyond known survival predictors such as cancer stage and performance status, a com...

Association of Neighborhood Deprivation With Breslow Thickness in Head and Neck Cutaneous Melanoma

ABSTRACT Objectives To characterize the role of neighborhood‐level disadvantage measured via Area Deprivation Index (ADI) in surgical melanoma management by understanding its association with melanoma thickness and other key clinical outcomes. Methods This is a retrospective coho...

Time-Temperature-Transformation Diagrams to Navigate the Nucleation and Quenchability of Metastable α-Li₃PS4

α-Li₃PS₄ is a promising solid-state electrolyte with the highest ionic conductivity among its polymorphs. However, its formation presents a thermodynamic paradox: the α-phase is the equilibrium phase at high temperature and transforms to the stable γ-Li3PS4 polymorph when cooled...

From optimistic to overwhelmed: exploring health beliefs and barriers to oral anticancer medication adherence among cancer survivors

Abstract Purpose This study explored cancer survivors’ health beliefs about oral anticancer medications (OAMs) and examined how these beliefs influence adherence-related decision-making, while identifying barriers and strategies to support cancer management. Methods Twelve patien...

Histopathology and spatial transcriptomics jointly map myofiber-specific pathological programs in mTORC1-driven myopathy

Skeletal muscle is a structurally organized and functionally diverse organ composed of heterogeneous myofiber types and supporting non-myocyte populations that act in concert to generate force, regulate metabolism, and maintain systemic homeostasis. Myopathies occur in many diffe...

Equivalent Numeric Approved Identity of Passport and Immigration Papers -- The Next Generation Identification Program (NGI) [A Short Introduction]

We express an interest to Equivalent Numeric Approved Identity of Passport and Immigration Papers. [We are making a submission to the Journal of Banking and Financial Technology].

Association between exposure to air pollution and age at natural menopause: The Study of Women's Health Across the Nation.

CONTEXT: Air pollution is a recognized risk factor for women's subfertility, yet its association with the timing of natural menopause remains understudied. OBJECTIVES: To examine the association between exposure to ambient air pollution and age at natural menopause (ANM). DESIGN...

The Star Formation History and Evolution of the Ultra-Diffuse M81 Satellite F8D1

Abstract We present deep Hubble Space Telescope (HST) imaging of one of the nearest ultra-diffuse galaxies (UDGs) outside of the Local Group: F8D1, a satellite of M81 known to be tidally disrupting. UDGs are an enigmatic and diverse population, with evolutionary pathways ranging...

Grassroots Governance for Sustainable Environmental Planning: Examining Manila Bay as Limit Case for Participatory Policy Implementation

Abstract In governance and social policies for environmental planning, communities are often engaged for decision-making, aspiring to fulfill democratic ideals. However, community participation is usually limited to decision making; policy implementation seems outside the scope a...

Between the Party-State and the Global Order: The Evolution of Civil Society in Vietnam in Historical Perspective

This article examines the broad evolution of civil society in Vietnam in the last three decades within the context of global and domestic political changes. As the country became closely tied to the global economy and society, civil society underwent a rapid expansion before the...

When I Care More Than the Department Does: Research Value (In)Congruence and Faculty Epistemic Exclusion Experiences

Academia values research that is quantitative, generalizable, or viewed as “objective” (centered research values), while research that is qualitative, concerned with marginalized groups, or social justice focused (marginalized research values) is often dismissed as subjective or...

Rare variant effect estimation and polygenic risk prediction

Abstract Due to their low frequency, estimating the effect of rare variants is challenging. Here, we propose RareEffect, a method that first estimates gene- or region-based heritability and then each variant effect size using an empirical Bayes approach. Our method uses a varianc...

DOSE: An open-source, iOS watch-based tool for experience sampling

Smartwatches facilitate low-burden rapid-access micro-interactions, making them ideal for Experience Sampling Methods (ESMs). Despite the Apple Watch being the most popular smartwatch in the U.S., it has yet to be utilized in ESM studies due to a lack of accessible frameworks tha...